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Bipolar mixed episodes increase significantly under DSM-5

Bipolar mixed episodes increase significantly under DSM-5

Using the most recent diagnostic criteria increases the prevalence of mixed features in patients with bipolar disorder more than threefold, study findings indicate.

13 Nov 2014

FDA approves Contrave extended-release tablets for chronic weight management

FDA approves Contrave extended-release tablets for chronic weight management

Takeda Pharmaceuticals U.S.A., Inc. and Orexigen® Therapeutics, Inc. jointly announced today that the U.S. Food and Drug Administration has approved Contrave® extended-release tablets as an adjunct to a reduced-calorie diet and increased physical activity for chronic weight management in adults with an initial body mass index of 30 kg/m2 or greater (obese), or 27 kg/m2 or greater (overweight) in the presence of at least one weight-related comorbid condition.

11 Sep 2014

Bipolar II disorder course mapped in Japanese patients

Bipolar II disorder course mapped in Japanese patients

The course of bipolar II disorder can follow several distinct trajectories, with a major depressive episode being the most common presenting feature, a study of Japanese patients suggests.

14 Aug 2014

Patients in new DSM-5 bipolar category ‘deserve attention’

Patients in new DSM-5 bipolar category ‘deserve attention’

People who fall into the DSM-5 Other Specified Bipolar and Related Disorders category carry a significant clinical burden, a study shows.

19 Jun 2014

Bipolar at-risk criteria identify ‘relevant clinical minority’

Bipolar at-risk criteria identify ‘relevant clinical minority’

A set of ultra-high-risk criteria for bipolar disorder identifies a group of help-seeking patients with a high rate of new-onset mania or hypomania over the following year, say researchers.

19 May 2014

Smartphone app shows promise for detecting early signs of mood changes in people with bipolar disorder

Smartphone app shows promise for detecting early signs of mood changes in people with bipolar disorder

A smartphone app that monitors subtle qualities of a person's voice during everyday phone conversations shows promise for detecting early signs of mood changes in people with bipolar disorder, a University of Michigan team reports.

8 May 2014

Electrode placement affects subthalamic nucleus stimulation outcomes

Electrode placement affects subthalamic nucleus stimulation outcomes

Researchers have identified factors associated with motor, cognitive and mood outcomes after deep-brain stimulation (DBS) of the subthalamic nucleus in a large cohort of patients with Parkinson’s disease.

4 Apr 2014

Diagnostic errors common among patients with bipolar disorder

Diagnostic errors common among patients with bipolar disorder

Russian study data bolster the existing body of evidence showing that bipolar disorder is often misdiagnosed as depression.

5 Mar 2014

Comorbid OCD and bipolar disorder should be treated as mood disorder

Comorbid OCD and bipolar disorder should be treated as mood disorder

Most patients with both bipolar disorder and obsessive–compulsive disorder should be treated as having bipolar disorder, researchers suggest.

21 Feb 2014

Bipolar disorder could be more common than thought

Bipolar disorder could be more common than thought

Bipolar disorder may be underdiagnosed in epidemiological surveys, say researchers who studied data from the World Mental Health surveys.

4 Feb 2014

Simple hypomania checklist detects bipolar II disorder

Simple hypomania checklist detects bipolar II disorder

A 15-item hypomania checklist has shown potential for differentiating bipolar disorder, particularly type II, from major depressive disorder.

30 Jan 2014

Bipolar screening tools not tailored to young people

Bipolar screening tools not tailored to young people

Current screening tools for bipolar disorder are poorly validated in the age group most at risk for developing the condition, say researchers.

9 Jan 2014

Conversion from psychotic depression to bipolar disorder explored

Conversion from psychotic depression to bipolar disorder explored

Danish researchers have identified a range of characteristics in people with psychotic depression that predict an increased risk for conversion to bipolar disorder.

21 Nov 2013

Obesity, bipolarity may have common mechanisms

Obesity, bipolarity may have common mechanisms

The presence of obesity in patients with major depression could be a sign of underlying bipolarity, say researchers.

12 Nov 2013

Mood disorder subtypes remain in the family

Mood disorder subtypes remain in the family

Psychosis, mania, and depression are unlikely to have shared hereditary causes, report researchers in Molecular Psychiatry.

8 Nov 2013

Bipolar mania and depression independently inherited

Bipolar mania and depression independently inherited

Bipolar mania and depression may be independently inherited in families, findings of a US study suggest.

7 Nov 2013

First-episode type predicts morbidity, disease course in bipolar disorder

First-episode type predicts morbidity, disease course in bipolar disorder

Study findings suggest that the type of first episode in patients with bipolar disorder can predict the type and degree of future morbidity, as well as the disease course.

5 Nov 2013

Postpartum diagnostic switches likely in depressed women

Postpartum diagnostic switches likely in depressed women

Women with major depression should be monitored for emerging symptoms of hypomania during the postpartum period, say researchers.

23 Oct 2013

Bipolar disorder ‘distinct’ from borderline personality disorder

Bipolar disorder ‘distinct’ from borderline personality disorder

Researchers say that there are clear clinical differences between depressed patients with bipolar II disorder and those with borderline personality disorder, which supports the two being treated as distinct conditions.

8 Oct 2013

Case for targeting perfectionism in patients with bipolar disorder

Case for targeting perfectionism in patients with bipolar disorder

Anxiety and stress symptoms may mediate the association between perfectionism and depressive symptoms in patients with bipolar disorder in a “transdiagnostic” process, say researchers.

16 Sep 2013

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