Hyponatremia News and Research

RSS

Hyponatremia refers to an abnormally low level of the electrolyte sodium (salt) in the blood. Sodium is an electrolyte that helps regulate the amount of water within and around cells in the body.

FDA approves Samsca tablets (tolvaptan) to treat hyponatremia

The U.S. Food and Drug Administration has approved Samsca tablets (tolvaptan) to treat hyponatremia, an abnormally low concentration of sodium in the blood.

8 May 2009

FDA approves Symbyax for treatment-resistant depression

The U.S. Food and Drug Administration (FDA) has approved a new indication for Symbyax (olanzapine and fluoxetine HCl capsules), Eli Lilly and Company has announced.

23 Mar 2009

Savella - Fibromyalgia treatment approved by FDA

Forest Laboratories, Inc. and Cypress Bioscience, Inc. have announced that Savella (milnacipran HCl), a selective serotonin and norepinephrine dual reuptake inhibitor, was approved by the U.S. Food and Drug Administration (FDA) for the management of fibromyalgia.

19 Jan 2009

New data on ZOLINZA (vorinostat) in combination with Bortezomib

Results from two Phase 1 studies of ZOLINZA (vorinostat), Merck's oral histone deacetylase (HDAC) inhibitor, administered in combination with bortezomib, showed early anti-tumor activity in patients with relapsed and/or refractory multiple myeloma, including those previously treated with and no longer responding to bortezomib.

10 Dec 2008

Desmopressin for bed-wetting linked to convulsions in children

Australian authorities have issued a warning regarding a drug sometimes used to treat primary nocturnal enuresis (bed-wetting) in children.

3 Aug 2008

FDA advisory committee recommends approval of Tolvaptan for hyponatremia

The U.S. Food and Drug Administration (FDA) Advisory Committee on Cardiovascular and Renal Drugs voted to recommend the approval of tolvaptan, Otsuka Pharmaceutical Development & Commercialization, Inc.'s (OPDC) investigational treatment for patients with hyponatremia.

25 Jun 2008

Predicting outcomes before and after liver transplants

The most appropriate system for organ allocation for liver transplants is a subject of continuing debate.

3 Aug 2007

Investigational drug tolvaptan treats hyponatremia

Results of the two largest studies on hyponatremia, SALT-1 and SALT-2, presented Nov. 14 at the American Heart Association's Scientific Sessions in Chicago, found that the investigational drug tolvaptan treated hyponatremia -- water intoxication -- faster and more effectively than available treatments.

14 Nov 2006

New drug lixivaptan reduces excess fluid build-up in patients with congestive heart failure

Researchers believe they may have identified a new agent to reduce the excess fluid build-up in patients with congestive heart failure, one that avoids the relative sodium-depleting effects of diuretics, now the most commonly used drugs for this purpose.

3 May 2006

Gatorade appears effective in correcting dehydration and improving bowel symptoms

A double-blind trial of oral rehydration solutions for children with diarrhea and vomiting related to acute viral gastroenteritis found that Gatorade is as effective as Pedialyte in correcting dehydration and improving bowel symptoms.

1 Nov 2005

Potential use of NH neurotransmitters as novel source for psychiatric drugs

Physiologists and medical researchers have long recognized the important endocrine roles played by the pituitary hormones oxytocin (OT) and vasopressin (VP) on peripheral systems in lactation, uterine contraction and urine concentration.

19 Jul 2005

Spontaneous contractions suppressed in late-term rat pregnancy

A long-time aim of obstetrical research has been to find agents that could delay or diminish pre-term labor because even today pre-term birth is a leading cause of infant mortality and morbidity.

19 Jul 2005

Runners must hydrate properly

Seeking to clarify complex issues involving hydration for athletes, the American College of Sports Medicine (ACSM) today reiterated its statements on hyponatremia and dehydration for athletes during endurance events.

27 Apr 2005

Serum sodium level is a major predictor of a poor prognosis for heart failure patients

Research presented today at the American College of Cardiology's Scientific Sessions in Orlando pinpoints a major marker of a poor prognosis for heart failure, hyponatremia, or a lower than normal concentration of serum or blood sodium.

7 Mar 2005

Biochemical marker aids prognosis in liver transplant patients

A new study on whether the model used to identify patients most in need of a liver transplant can be improved upon found that measuring serum sodium in potential transplant patients helps to better predict those with a poor prognosis.

20 Feb 2005

A low salt diet can be extremely dangerous for elderly people

Professor Füsgen presented his findings at the European Geriatrics Congress in Vienna, which ended yesterday (September 19). They show that the symptoms of hyponatraemia (low sodium level in the blood), which are tiredness, difficulty in concentrating and loss of balance, can develop into confusion and even coma if left untreated.

20 Sep 2004