Hypoplastic Left Heart Syndrome News and Research

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Hypoplastic left heart syndrome (HLHS) is a problem with the heart’s structure that is present at birth (congenital). It is a group of related defects that, together, mean that the left side of the heart is underdeveloped. Normally, oxygen-poor blood is pumped through the right side of the heart to the lungs, where it gains oxygen and returns to the left side of the heart. The oxygen-rich blood is then pumped from the left side of the heart to the rest of the body. At birth, all babies also have two connections, or shunts, between the two sides of the heart; however, within a few days of birth these connections close.

Tel Aviv University develops innovative algorithms to combat Intra-uterine growth restrictions for healthy babies

When a fetus is smaller than expected for the number of weeks of pregnancy, due to associated problems like a poorly developed heart, health concerns as severe as brain damage can result.

11 Nov 2009

Boy born with half a heart survives and thrives

Rhonda Ellison was six months pregnant when she and her husband, James Gaines, got the kind of news all parents dread going into an ultrasound: something was wrong with their baby. They needed to go to the Children's Heart Center at Golisano Children's Hospital.

27 May 2009

Environment plays role in hypoplastic left heart syndrome

A congenital heart disease that often leads to death in newborns is significantly more common during the summer, leading researchers to believe that the environment, and not just genes that affect the heart, may play a role in causing "mini-epidemics" of this disease.

30 Mar 2009

Cardiopulmonary bypass for child heart surgery does not affect IQ

The use of cardiopulmonary bypass does not cause short-term neurological problems in children and teenagers after surgery for less complex heart defects, according to pediatric researchers.

11 Nov 2008

For children with heart disease, a risk of attention and behavior problems

Schoolchildren who required surgery as infants for congenital heart disease (CHD) run a significant risk of having problems with inattention and hyperactivity, and often require remedial services in school.

7 Apr 2008

For babies with specific complex heart defects, death risk is far lower at most experienced hospitals

Each year, thousands of babies are born with severe heart defects that must be operated on within days or weeks of their birth.

17 Dec 2007

Hypoplastic left heart syndrome likely caused by genetic factors

Hypoplastic Left Heart Syndrome (HLHS), a severe cardiovascular malformation that is difficult to treat and often lethal, is caused primarily by genetic factors, according to a new study by researchers at Cincinnati Children's Hospital Medical Center.

11 Oct 2007

John Cheatham receives prestigious award for work on congenital heart disease

The Pediatric Interventional Cardiac Symposium (PICS) & Adult Interventional Cardiac Symposium (AICS) Lifetime Achievement Award for 2007 was recently presented to John P. Cheatham, MD, Co-Director of The Heart Center at Columbus Children's Hospital and Professor of Pediatrics & Internal Medicine at The Ohio State University College of Medicine.

11 Sep 2007

Researchers shed light on congenital diaphragmatic hernia

The diaphragm, a shelf of muscle that separates the chest cavity from the abdominal cavity, is critical to sustaining life.

8 Jun 2007

Treating congenital heart defects in babies still in the womb

Researchers at Children's Hospital Boston and Brigham and Women's Hospital reviewed the cases of 80 fetuses who had prenatal cardiac interventions during a six-year period (most often to avert hypoplastic left heart syndrome.

30 Mar 2007

Baby Grace goes home after having heart surgery as a fetus

A baby girl, who had the world's first heart "stent" procedure in the womb was discharged from hospital on Friday and went home 17 days after her birth.

31 Jan 2006

Gene defect linked to heart disease

Researchers at the University of Texas Southwestern Medical Center in Dallas, have found by studying DNA from 11 members of one family, who suffered from aortic heart disease, a genetic mutation that causes a common birth defect and contributes to heart disease in adults.

19 Jul 2005

Study shows mutation in NOTCH1 gene causes aortic valve disease

By studying five generations of a Dallas family, UT Southwestern Medical Center researchers have discovered that a mutation in a key gene causes aortic valve disease, a common heart birth defect as well as a major contributor to adult heart disease.

18 Jul 2005

How heart is formed in the embryo helps explain congenital heart disease

Children's Hospital of Pittsburgh Cardiologist Bradley B. Keller, MD, and his research team are discovering details in the lab that explain how the heart is formed in the embryo. This knowledge improves the chances of doctors identifying fetuses who can benefit from intervention to treat congenital defects.

5 Apr 2005

Parents and siblings of infants born with severe abnormalities of the left side of the heart should also be screened for heart problems

Brothers and sisters as well as parents of infants born with severe, life-threatening abnormalities of the left side of the heart should be screened for less severe, but related, heart problems, said researchers at Baylor College of Medicine in Houston.

7 Sep 2004

Researchers awarded $5 million to develop a pediatric heart assist device

Penn State researchers recently were awarded a $5 million contract from the National Heart, Lung, and Blood Institute of the National Institutes of Health to develop a pediatric heart assist device.

11 May 2004