Hypotension News and Research

RSS

AstraZeneca submits sNDAs for SEROQUEL XR for bipolar symptoms

AstraZeneca has announced that the company has submitted two separate supplemental New Drug Applications (sNDAs) to the U.S. Food and Drug Administration (FDA) for once-daily SEROQUEL XR (quetiapine fumarate) Extended-Release Tablets to seek approval for the treatment of manic episodes associated with bipolar disorder and the treatment of depressive episodes associated with bipolar disorder.

3 Jan 2008

Caution on use of Vasopressin in septic shock

Vasopressin should be used with great caution for the treatment of hypotension in septic shock, according to results from an international research team published in the online open access journal Critical Care.

14 Dec 2007

Approval of Diovan (valsartan) in U.S. for hypertension in children and adolescents

Diovan (valsartan), an angiotensin receptor blocker or ARB, has been approved following a priority review by the U.S. Food and Drug Administration (FDA) for the treatment of high blood pressure in children and adolescents ages six to 16.

4 Dec 2007

Lidocaine lollipop helps prepare for upper GI endoscopy

Researchers at the American University of Beirut Medical Center (AUBMC) in Lebanon have found that administering a lidocaine lollipop as a single-agent anesthetic to patients undergoing an upper gastrointestinal (GI) endoscopy procedure eliminated the need for sedation in the majority of patients.

17 Oct 2007

Prevention of primary variceal bleeding

Beta blockers should be the first line of prevention against variceal bleeding in patients with cirrhosis and portal hypertension. While banding is similarly effective in reducing the incidence of such bleeding, it can have fatal complications and is more expensive.

10 Sep 2007

New blood pressure drug Tekturna benefits heart failure patients too

A new blood pressure drug called Tekturna made by Novartis has been found to benefit heart failure patients also.

4 Sep 2007

The first clinically available oral direct renin inhibitor shows promise in heart failure

Drugs that block a hormonal cascade, known as the renin-angiotensin-aldosterone system (RAAS), help patients with heart failure. Direct renin inhibitors (DRIs) block the RAAS at its first and rate-limiting step.

2 Sep 2007

Diovan (valsartan) granted pediatric exclusivity by FDA

Diovan (valsartan) has been granted pediatric exclusivity by the US Food and Drug Administration (FDA) based on studies conducted in children with high blood pressure.

13 Aug 2007

Neck muscles could play a crucial role in controlling blood pressure, heart rate and breathing

A chance discovery in the lab has helped University of Leeds scientists to show how the treatment for a stiff neck could do wonders for your blood pressure.

3 Aug 2007

Call for renewed efforts to develop standard definitions and terminology for anesthesia

The absence of standardized definitions for events and outcomes during and after anesthesia for surgery has major implications for anesthesiology research and practice, as well as for public perceptions of anesthesia care, according to an editorial by two leading anesthesiology researchers.

24 Jul 2007

Easing agonising deaths of terminally ill babies "tantamount to euthanasia"

A doctor in Scotland who gave a paralysing drug to two terminally ill babies, has told a General Medical Council (GMC) panel he felt the children were suffering.

10 Jul 2007

Use of blockers and statins to prevent heart complications during surgery questioned

The use of drugs to prevent heart complications during surgery is called into question in this week's BMJ.

23 Jun 2007

Reversal of coma with an injection of glue

Neurosurgeons and neuroradiologists at Cedars-Sinai Medical Center injected a biosynthetic “glue” to seal off a spinal fluid leak and restore a comatose patient to consciousness.

28 May 2007

FDA approves skin patch designed to treat symptoms of early Parkinson's disease

Rotigotine is a drug not previously approved in the United States. Neupro is the first transdermal patch approved for the treatment of symptoms of Parkinson's disease.

10 May 2007

New treatment Candida fungi - fewer side effects

A new treatment for Candida species of fungi which can cause thrush and sepsis (a life-threatening infection leading to fever, hypotension, and shock) has proven equally effective as the existing treatment in a drug trial.

26 Apr 2007

New device increases circulation and blood flow to vital organs during CPR

In the United States, a person's chance of surviving cardiac arrest is probably much lower than most people realize: 17-19 percent in hospitals.

15 Apr 2007

New understanding of blood pressure gene could lead to new treatments

Research by scientists at UCL (University College London) has clearly demonstrated for the first time the structure and function of a gene crucial to the regulation of blood pressure. The discovery could be important in the search for new treatments for illnesses such as heart disease, the UK's biggest killer.

5 Feb 2007

Study shows Diovan reduced urinary protein excretion in patients with type 2 diabetes and high blood pressure

In patients with high blood pressure and type 2 diabetes, the blood pressure-lowering medication Diovan (valsartan) significantly reduced urinary protein excretion, with high doses providing the greatest sustained reduction , according to data presented at the Amer ican Heart Association's (AHA) Annual Scientific Sessions.

13 Nov 2006

NicOx announces EMEA approval of Naproxcinod study plan

NicOx S.A today announced that it has received scientific advice on its proposed phase 3 clinical plan for naproxcinod (HCT 3012) from the Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency (EMEA).

17 Oct 2006

Endovascular repair of thoracic and abdominal aortic diseases as an alternative to open surgery in patients at high surgical risk

World Congress of Cardiology Report - Acute aortic syndromes, such as large thoracic and abdominal aortic aneurysms with impending rupture, complicated acute type B dissections, traumatic rupture of thoracic aorta, still represent life-threatening conditions.

5 Sep 2006