Hypothalamus News and Research

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The Hypothalamus is the area of the brain that controls body temperature, hunger, and thirst.

SH2B1 protein plays a key role in controlling body weight, response to insulin and leptin

A single protein in brain cells may act as a linchpin in the body's weight-regulating system, playing a key role in the flurry of signals that govern fat storage, sugar use, energy balance and weight, University of Michigan Medical School researchers report.

29 Jan 2007

A central thermogenic-like mechanism in feeding regulation

During periods of fasting, brain cells responsible for stimulating the appetite make sure that you stay hungry.

2 Jan 2007

Research offers hope for alcoholics

Scientists at Melbourne's Howard Florey Institute have discovered a system in the brain that stops an alcoholic's craving for alcohol, as well as prevent relapse once they have recovered from alcohol addiction.

12 Dec 2006

Stay cool and live longer!

If new research is to be believed living longer may simply be a case of staying cool.

6 Nov 2006

Newly discovered molecule could lead to new treatments for obesity

Japanese scientists have found a molecule which is responsible for making mammals feel full, and they believe the discovery could lead to new ways to treat obesity in humans.

3 Oct 2006

Food like an addictive drug for some people

Researchers in the U.S. have found that the same brain circuits are involved when obese people fill their stomachs as when drug addicts think about drugs and the discovery they say suggests an association between overeating and addiction.

3 Oct 2006

Insulin receptor stops progression of Alzheimer's disease

Stimulation of a receptor in the brain that controls insulin responses has been shown to halt or diminish the neurodegeneration of Alzheimer's disease, providing evidence that the disease can be treated in its early stages, according to a study by researchers at Rhode Island Hospital and Brown Medical School.

21 Sep 2006

Leptin could combat type 2 diabetes

University of Florida researchers have discovered the appetite-controlling hormone leptin could also combat type 2 diabetes, a disease that has become a growing problem in the United States as more Americans pack on extra pounds.

21 Sep 2006

Some brains wired to encourage fidgeting

Some brains may be wired to encourage fidgeting and other restless behaviors that consume calories and help control weight, according to new research published by The American Physiological Society.

14 Aug 2006

Serotonin reciprocally regulates melanocortin neurons to modulate food intake

Some of the most important weight-loss drugs work by enhancing the effect of the brain chemical serotonin.

24 Jul 2006

Cause of neurodegeneration in Huntington's disease discovered

The severe neurodegeneration associated with Huntington's disease may result from molecular mutations that block the transport of nutrients within cells.

1 Jun 2006

Signaling pathway mTOR plays a role in the brain's ability to sense how much energy the body has available

A cell-signaling pathway in the brain that is linked to the development of cancer and diabetes is also a key part of networks that regulate food intake, say University of Cincinnati (UC) researchers.

12 May 2006

Identification of CPT1c gene that the brain needs to manage body weight

Working with genetically engineered mice, Johns Hopkins scientists have interfered with the brain's ability to control an animal's response to a high-fat diet.

3 May 2006

Hap1 protein could lead to future drug targets for eating disorders

Researchers have discovered how the protein Hap1, which is abundant in the brain's hypothalamus, serves as the link between circulating insulin in the blood and the neural circuitry that controls feeding behavior in mice.

16 Apr 2006

Research provides clues to obesity's cause

Hot fudge sundaes and french fries aside, new research suggests obesity is due at least in part to an attraction between leptin, the hormone that signals the brain when to stop eating, and a protein more recently associated with heart disease.

13 Apr 2006

Men's and women's brains behave differently

A key part of the brain involved in processing emotionally-influenced memories acts differently in men and women, even in the absence of stimuli, UC Irvine researchers have found.

11 Apr 2006

Leptin may lead to new approaches for curbing appetite

11 Apr 2006

Anabolic steroids flip the adolescent brain's switch for aggression

Anabolic steroids not only make teens more aggressive, but may keep them that way into young adulthood. The effect ultimately wears off but there may be other, lasting consequences for the developing brain.

27 Feb 2006

Steroids trigger long lasting aggression in teens

According to a U.S. study steroids may have a lasting effect on teenagers' brains, and could even flip the adolescent brain's switch for aggression which may last for at least two years.

27 Feb 2006

Hormone discovered in bird brains also plays major role in mammalian reproductive system

University of California, Berkeley, researchers have discovered a new actor in the mammalian reproductive system, a hormone that fills a role long suspected, but until now undetected.

7 Feb 2006