Hypoxia News and Research

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Hypoxia is a condition in which there is a decrease in the oxygen supply to a tissue. In cancer treatment, the level of hypoxia in a tumor may help predict the response of the tumor to the treatment.

Brain metastases hijack neuron-supporting cells to resist chemotherapy

Cancer that spreads to other organs finds a particularly inviting hideout in the brain, where these metastases are usually far harder to treat than they are in other locations.

20 Apr 2009

New light-based system reveals breast tumor oxygen status

Light directed at a breast tumor through a needle can provide pathologists with biological specifics of the tumor and help oncologists choose treatment options that would be most effective for that individual patient.

1 Apr 2009

Genetic mechanism in mole rats can be targeted in cancer research

"When we understand how the subterranean mole rat developed these mechanisms for survival, we may be able to understand why they are so destructive in humans," Prof. Aaron Avivi of the University of Haifa said.

15 Mar 2009

The obesity paradox

It's called the obesity paradox. Although obese people are more apt to suffer from inflammatory diseases, such as diabetes, heart disease, and stroke, they are also more likely to survive a major attack caused by one of those conditions.

26 Feb 2009

Two compounds show great promise for cerebral palsy

Two compounds developed by Northwestern University chemists have been shown to be effective in pre-clinical trials in protecting against cerebral palsy, a condition caused by neurodegeneration that affects body movement and muscle coordination.

25 Feb 2009

Dialysis patients living at higher altitudes have lower rate of death

Compared to dialysis patients living near sea level, dialysis patients living at an altitude higher than 4,000 feet have a 12-15 percent lower rate of death, according to a study in the February 4 issue of JAMA.

5 Feb 2009

Dialysis patients residing at higher altitude have lower rate of death

3 Feb 2009

Scientists discover protein critical for the growth of pancreatic cancer

Researchers at Stanford University School of Medicine have identified a protein critical for the growth of pancreatic cancer.

2 Feb 2009

Researchers show how anthracycline class of chemotherapeutics block blood vessel growth, slow cancer spread

Researchers at the Johns Hopkins University School of Medicine have discovered how a whole class of commonly used chemotherapy drugs can block cancer growth.

21 Jan 2009

Cell transplantation and diabetes: New sites, new devices

Early attempts at islet cell transplantation to treat diabetes date to the nineteenth century, decades before the discovery of insulin in the 1930s.

21 Jan 2009

Control of blood vessels a possible weapon against obesity

Mice exposed to low temperatures develop more blood vessels in their adipose tissue and metabolise body fat more quickly, according to a new study from Karolinska Institutet. Scientists now hope to learn how to control blood vessel development in humans in order to combat obesity and diabetes.

7 Jan 2009

Researchers gain new insight into cancer metastasis

Few things are as tiresome as house hunting and moving. Unfortunately, metastatic cancer cells have the relocation process down pat. Tripping nimbly from one abode to another, these migrating cancer cells often prove far more deadly than the original tumor.

5 Jan 2009

Old Digitalis-based drugs show promise as a treatment for cancer

Digitalis-based drugs like digoxin have been used for centuries to treat patients with irregular heart rhythms and heart failure and are still in use today.

5 Jan 2009

Cardiovascular system proteins play a role in Alzheimer's

Researchers have found that two proteins which work in tandem in the brain's blood vessels present a double whammy in Alzheimer's disease.

22 Dec 2008

New advance in the treatment of sickle cell anaemia

Sickle cell anaemia is a genetic disease characterised by the sickling of red blood cells in patients suffering from hypoxia (around 100,000 cases in Europe and North America).

25 Nov 2008

FDA approves tapentadol immediate-release tablets for pain in adults

Millions of Americans with moderate to severe acute pain and their health-care providers will soon have a new treatment option.

21 Nov 2008

Doctors' questions about end-of-life legalities may result in patient pain

When treatment options dwindle or are exhausted, terminally ill-patients often opt for pain management and comfort over life-extending therapies.

16 Nov 2008

Doctors' questions about end-of-life legalities may result in patient pain

When treatment options dwindle or are exhausted, terminally ill-patients often opt for pain management and comfort over life-extending therapies. However, a team of researchers from Wake Forest University Baptist Medical Center, University of Rochester Medical Center and Unity Health System, report that a lack of thorough understanding about the laws governing end-of-life care may be leaving many medical providers with an ethical dilemma and causing some terminally-ill patients considerable, unnecessary pain.

13 Nov 2008

Human papillomavirus helps cervical and head and neck cancers resist treatment and grow and spread

The human papillomavirus (HPV) allows infected cervical and head and neck cancer cells to maintain internal molecular conditions that make the cancers resistant to therapy and more likely to grow and spread, resulting in a poor prognosis for patients, researchers with UCLA's Jonsson Cancer Center found.

4 Nov 2008

Discovery of genetic switch critical for cell survival in Hypoxia

Researchers at the University of California, San Diego School of Medicine have identified a critical metabolic "switch" in fruit flies that helps oxygen-deprived cells survive. "A transcriptional suppressor, called hairy, is crucial for reducing the mismatch between supply and demand of oxygen," said Dan Zhou, first author on the study, published October 17 in the open-access journal PLoS Genetics.

21 Oct 2008

Hypoxia News and Research

Further Reading

Brain metastases hijack neuron-supporting cells to resist chemotherapy

New light-based system reveals breast tumor oxygen status

Genetic mechanism in mole rats can be targeted in cancer research

The obesity paradox

Two compounds show great promise for cerebral palsy

Dialysis patients living at higher altitudes have lower rate of death

Dialysis patients residing at higher altitude have lower rate of death

Scientists discover protein critical for the growth of pancreatic cancer

Researchers show how anthracycline class of chemotherapeutics block blood vessel growth, slow cancer spread

Cell transplantation and diabetes: New sites, new devices

Control of blood vessels a possible weapon against obesity

Researchers gain new insight into cancer metastasis

Old Digitalis-based drugs show promise as a treatment for cancer

Cardiovascular system proteins play a role in Alzheimer's

New advance in the treatment of sickle cell anaemia

FDA approves tapentadol immediate-release tablets for pain in adults

Doctors' questions about end-of-life legalities may result in patient pain

Doctors' questions about end-of-life legalities may result in patient pain

Human papillomavirus helps cervical and head and neck cancers resist treatment and grow and spread

Discovery of genetic switch critical for cell survival in Hypoxia

One Health, One Mission: The World Organisation for Animal Health on the AMR Frontline

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