I Cell Disease News and Research

RSS

PCORI Board awards $18 million for two new studies on sickle cell disease

The Patient-Centered Outcomes Research Institute Board of Governors today approved about $18 million to fund two studies comparing different ways to manage the transition of people with sickle cell disease from pediatric to adult care.

13 Sep 2017

Research reveals LEGO-like stacking of protein complexes

When hemoglobin undergoes just one mutation, the protein complexes stick to one another, stacking like LEGO blocks to form long, stiff filaments.

29 Aug 2017

Scientists develop new system to identify and characterize regulatory DNA sequences

Scientists from the Children's Medical Center Research Institute at UT Southwestern have developed an innovative system to identify and characterize the molecular components that control the activities of regulatory DNA sequences in the human genome.

24 Aug 2017

Expert highlights CRISPR’s applications, limitations, and ethical concerns

"Good morning, doctor, I am here for my gene editing appointment." In the future, could this be a greeting heard in physician offices around the world? With the introduction of CRISPR technology, genetic material can now be more easily and precisely edited, even creating changes that can subsequently be inherited by offspring.

1 Aug 2017

Computer models provide new details of how sickle cell disease manifests inside red blood cells

Computer models developed by Brown University mathematicians show new details of what happens inside a red blood cell affected by sickle cell disease.

28 Jul 2017

First in-car study of rush hour pollution finds alarming results

The first in-car measurements of exposure to pollutants that cause oxidative stress during rush hour commutes has turned up potentially alarming results.

21 Jul 2017

Researchers show how hematopoietic stem cells detect and react to infections

Researchers at the University of Zurich have shown for the first time that hematopoietic stem cells detect infectious agents themselves and begin to divide - that is, without signals from growth factors.

20 Jul 2017

Infographic displays facts and information about stem cells, cord blood

Over 40,000 people have successfully stored stem cells with Smart Cells, however the industry is still relatively unknown and often subject to misinformation. In a bid to increase awareness and understanding of stem cell collection at birth, Smart Cells have created an informative infographic.

17 Jul 2017

New program gives free legal help to families for health-related issues

Chicago families with kids who have complicated medical conditions now have easier access to legal help, thanks to a new partnership between the University of Illinois at Chicago and Legal Council for Health Justice.

11 Jul 2017

New treatment receives FDA approval to reduce complications of sickle cell disease

The U.S. Food and Drug Administration today approved Endari (L-glutamine oral powder) for patients age five years and older with sickle cell disease to reduce severe complications associated with the blood disorder.

7 Jul 2017

MSU researcher developing new miniature models to study heart disease and sickle cell anemia

A Mississippi State University researcher is developing new miniature models to better understand the factors that lead to heart disease and sickle cell anemia.

24 Jun 2017

Lipoprotein abnormalities linked to vaso-occlusive events in patients with sickle cell disease

An article published in Experimental Biology and Medicine (Volume 242, Issue 12, June, 2017) links imbalances in lipoprotein metabolism with vaso-occlusive events in patients with sickle cell disease

23 Jun 2017

Survivors of childhood diseases struggle to find care as adults

Rachael Goldring was born with congenital heart disease. Had she been born a few decades earlier, she probably would have died as a baby. Now 24, Goldring is part of a population of patients who present new challenges to a health care system unaccustomed to dealing with survivors of once-fatal conditions.

22 Jun 2017

New cancer drug shows promise to treat leukemia in mouse models

Almost 6,000 new cases of acute lymphoblastic leukemia, or ALL, are expected to be diagnosed this year in the United States. The blood cancer can affect both children and adults.

9 Jun 2017

WHO announces new flagship programs for African region over next two years

The World Health Organization’s Regional Director for Africa announced today four new flagship programs for the region over the next two years, including a major push on adolescent health and the creation of regional emergency hubs.

26 May 2017

Children surviving chronic health conditions may suffer from brain function issues

Survival rates continue to rise for children living with once-fatal chronic pediatric health conditions. But their survival comes at a cost: many experience long-term neurocognitive deficits.

17 May 2017

New study explores safety of exercise in children with sickle cell disease

While regular exercise is known to reduce inflammation over time, it actually increases inflammation in the short term.

16 May 2017

MUSC researchers provide first systemic evidence for safe use of tPA in stroke patients with SCD

Adult patients with sickle cell disease (SCD) who experience a stroke caused by a clot (i.e., ischemic strokes or IS) can be treated safely with tissue plasminogen activator (tPA) if they qualify, report investigators at the Medical University of South Carolina and elsewhere in the March 2017 issue of Stroke.

12 Apr 2017

Researchers develop robust technique for efficient manufacture of red blood cells

Researchers have generated the first immortalised cell lines which allow more efficient manufacture of red blood cells.

23 Mar 2017

Genetic mutations underlying treatment resistance in NSCLC more dynamic than previously thought

The genetic mutations underlying treatment resistance in non-small cell lung cancer (NSCLC) are more complex and dynamic than previously thought.

17 Mar 2017