IHC News and Research

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Molecular insights: Detecting gene fusions offers new avenues for advanced cancer management

Study identifies gene fusions to understand their relationship with observed pathologies in cancer patients.

8 Aug 2023

Role of M2 macrophage-derived exosomes in controlling neutrophil-mediated tissue injury in sepsis

Researchers investigate whether M2 macrophage-derived exosomes could prevent inflammation-associated damage during sepsis.

7 Aug 2023

Tumor-derived GDF-15 suppresses immunotherapy response

Researchers evaluate the impact of tumor-derived GDF-15 on responses to anti-PD-1 immunotherapy.

26 Jul 2023

New brain-penetrant agonist shows promise in protecting dopamine neurons for Parkinson's disease treatment

Researchers reported on Nurr1 as a promising therapeutic target for managing Parkinson's disease (PD).

20 Jul 2023

How does SARS-CoV-2 affect the placenta during pregnancy?

Researchers examine host responses to SARS-CoV-2 within the placenta using transcriptomics.

12 Jul 2023

Breaking barriers: hydrogel reservoir unleashes the potential of HSV-1 virotherapy in cancer

Researchers evaluated the therapeutic efficacy of Navoximod.

13 Jun 2023

HER2-targeted antibody drug conjugate shows encouraging responses, long-lasting clinical benefit in several tumor types

In a new study of trastuzumab deruxtecan, a HER2-targeted antibody drug conjugate, researchers observed encouraging responses and long-lasting clinical benefit in several tumor types.

5 Jun 2023

Omicron BA.5 variant demonstrates increased neuroinvasiveness and pathogenicity in mice

Researchers assessed the extent of SARS-CoV-2 Omicron VOC BA.5 sub-VOC infection-associated brain infection and death.

5 Apr 2023

Targeting obesity: findings reveal a new molecular pathway involved in energy homeostasis regulation

Study outlines molecular mechanisms to aid the development of new therapies to manage obesity and associated health disorders.

29 Mar 2023

Detecting tissue-resident memory T cells in solid tumors

In this interview, NewsMedical talks with Cerba Research about in situ multiplex analysis of regulatory and effector T cells in tumors.

16 Mar 2023

Achieving immune cell checkpoint profiling

NewsMedical exchanges with Cerba Research on how to achieve immune cell checkpoint profiling of solid tumors by multiplex immunofluorescence.

From Cerba Research 16 Mar 2023

Researchers report a physical barrier against SARS-CoV-2 infection based on an inhalable bioadhesive hydrogel

Researchers developed spherical hydrogel inhalation for enhanced lung defense to protect against SARS-CoV-2 infections.

13 Feb 2023

Repression of endothelial TLR3 is a potential mechanism of SARS-CoV-2 infection-associated lung vascular remodeling

Researchers investigated whether endothelial TLR3 insufficiency contributes to lung vascular remodeling induced by SARS-CoV-2.

30 Jan 2023

Study generates a comprehensive genetic map to identify important genes that cause sarcoma

Several genes that cause sarcoma have been identified in the first comprehensive genetic map of sarcomas, generated by research led by Omico, the Garvan Institute of Medical Research and UNSW Sydney.

19 Jan 2023

Exploring bioinformatics approach for evaluating binding affinities of probable COVID-19 therapeutic decoys

Researchers developed a computational workflow based on molecular dynamic (MD) simulations and artificial neural network (ANN) to assess the SARS-CoV-2 spike (S) protein receptor-binding domain (RBD)-human angiotensin-converting enzyme 2 (hACE2) binding affinities of SARS-CoV-2 variants.

17 Jan 2023

Old antibiotic nitroxoline suggested as a treatment for MPOX

In a recent study posted to the bioRxiv* server, researchers in Germany investigated the effectiveness of the antibiotic nitroxoline against the currently circulating mpox viruses, previously called monkeypox virus (MPXV). This antibiotic has been used in Europe for about fifty years and has been proven effective in fighting biofilm infections.

3 Jan 2023

IHC News and Research

Molecular insights: Detecting gene fusions offers new avenues for advanced cancer management

Role of M2 macrophage-derived exosomes in controlling neutrophil-mediated tissue injury in sepsis

Tumor-derived GDF-15 suppresses immunotherapy response

New brain-penetrant agonist shows promise in protecting dopamine neurons for Parkinson's disease treatment

How does SARS-CoV-2 affect the placenta during pregnancy?

Breaking barriers: hydrogel reservoir unleashes the potential of HSV-1 virotherapy in cancer

HER2-targeted antibody drug conjugate shows encouraging responses, long-lasting clinical benefit in several tumor types

Omicron BA.5 variant demonstrates increased neuroinvasiveness and pathogenicity in mice

Targeting obesity: findings reveal a new molecular pathway involved in energy homeostasis regulation

Detecting tissue-resident memory T cells in solid tumors

Achieving immune cell checkpoint profiling

Researchers report a physical barrier against SARS-CoV-2 infection based on an inhalable bioadhesive hydrogel

Repression of endothelial TLR3 is a potential mechanism of SARS-CoV-2 infection-associated lung vascular remodeling

Study generates a comprehensive genetic map to identify important genes that cause sarcoma

Exploring bioinformatics approach for evaluating binding affinities of probable COVID-19 therapeutic decoys

Old antibiotic nitroxoline suggested as a treatment for MPOX

Study shows SARS-CoV-2 infection, replication and persistence in human brain tissues

Molecular and cellular similarities identified in the brains of SARS-CoV-2 and Alzheimer's disease patients

The role of bacteria in cancer growth

Researchers develop a new method to map the spatial evolution of cancers

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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