Ibuprofen News and Research

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Ibuprofen is a drug used to treat fever, swelling, pain, and redness by preventing the body from making a substance that causes inflammation. It is a type of nonsteroidal anti-inflammatory drug (NSAID). Ibuprofen is a propionic acid derivate and nonsteroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic, and antipyretic effects. Ibuprofen inhibits the activity of cyclo-oxygenase I and II, resulting in a decreased formation of precursors of prostaglandins and thromboxanes. This leads to decreased prostaglandin synthesis, by prostaglandin synthase, the main physiologic effect of ibuprofen. Ibuprofen also causes a decrease in the formation of thromboxane A2 synthesis, by thromboxane synthase, thereby inhibiting platelet aggregation.

Aspirin and ibuprofen may significantly reduce the risk of esophageal cancer among people with Barrett's esophagus

Aspirin and other nonsteroidal anti- inflammatory drugs, such as ibuprofen, may significantly reduce the risk of esophageal cancer among people with Barrett's esophagus, a precancerous condition associated with chronic heartburn that affects an estimated 1 million to 2 million Americans.

8 Nov 2005

Aspirin may prevent skin cancer

Australian scientists say that common drugs such as aspirin may hold the key to reducing the risk of developing skin cancer.

8 Nov 2005

Ibuprofen and naproxen combined with aspirin increase risk of gastrointestinal complications

Patients who combine the common over-the counter pain medications ibuprofen and naproxen with aspirin have a risk of gastrointestinal complications including ulcers, perforations and bleeding that is two to three times greater than patients who take these medications but do not combine them with aspirin.

1 Nov 2005

Regular use of ibuprofen may increase gastrointestinal bleeding

People who take high doses of ibuprofen on a regular basis are three times more likely to experience gastrointestinal (GI) bleeding than those who do not take painkillers.

1 Nov 2005

Research points way to more effective delivery of medicine around the body

New research showing how drugs stick to a key protein in the bloodstream could help to create drugs that are delivered more effectively to organs in the body.

13 Oct 2005

Long-term use of NSAIDs cuts the risk for oral cancer in smokers by half but increases risk of cardiovascular problems

An analysis of 20 years of data on the health of over 900 adults has found that long-term use of traditional nonsteroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen and naproxen, cuts the risk for oral cancer in smokers by half.

9 Oct 2005

Low-dose aspirin might prevent the cardiovascular damage known to arise from use of the painkiller rofecoxib (Vioxx)

Their findings that a chemical imbalance might underlie such damage could also lead to the development of anti-inflammatory drugs without the adverse side effects, the researchers said.

20 Sep 2005

Salicylate an active metabolite of aspirin - weakens lipid membranes

It's well known that high doses of aspirin can cause ulcers and temporary deafness, but the biochemical mechanism responsible for these phenomena has never been deciphered.

19 Sep 2005

Double whammy of vitamin D and anti-inflammatory zaps prostate cancer cells

Scientists from Stanford University say they have discovered that vitamin D, known as the "sunshine vitamin,"can limit the growth of prostate cancer cells when combined with non-steroidal anti-inflammatory drugs.

6 Sep 2005

Low doses of the active form of vitamin D and non-steroidal anti-inflammatory drugs form one-two punch against prostate cancer cells

Low doses of the active form of vitamin D and non-steroidal anti-inflammatory drugs, taken in combination, have been shown to act as a powerful one-two punch that knocks down the growth of prostate cancer cells.

1 Sep 2005

Extra-virgin olive oil tastes good and is also an anti-inflammatory

After a tasting experience at a molecular gastronomy meeting in Sicily, biologist Gary Beauchamp of Pennsylvania University decided to analyse freshly pressed extra-virgin olive oil and found a chemical that acted like ibuprofen in the oil.

31 Aug 2005

Taking aspirin longterm could reduce colorectal cancer risk

According to new report from the Nurses' Health Study (NHS), regular, long-term aspirin use can significantly reduce the risk of colorectal cancer.

24 Aug 2005

Aspirin use can significantly reduce the risk of colorectal cancer

A new report from the Nurse's Health Study finds that regular, long-term aspirin use can significantly reduce the risk of colorectal cancer, as suggested by several earlier studies.

23 Aug 2005

Epidemiological study links heart protection with non-aspirin, non-steroidal drugs

It is well known that aspirin, a non-selective, non-steroidal anti-inflammatory drug (NSAID) that inhibits cyclooxygenase (COX), reduces the risk of heart attack and stroke.

22 Aug 2005

Common non-aspirin painkillers linked to high blood pressure in women

Women who consume higher doses of non-aspirin painkillers are much more likely to develop high blood pressure than women who do not use them, according to research reported in Hypertension: Journal of the American Heart Association.

17 Aug 2005

New study shows even non-prescription painkillers raise blood pressure in women

According to a new U.S. study women who take higher doses of common, over-the-counter painkillers, such as Ibuprofen and even Tylenol, have higher blood pressure than women who do not.

16 Aug 2005

Ibuprofen can increase bleeding during surgery

Researchers from the Case Western Reserve University School of Dental Medicine recommend the discontinuation of ibuprofen prior to surgery to correct gum disease because blood loss is two times greater for those using the medication than those not taking it.

19 Jul 2005

Vioxx safe enough for Canadian market says health panel

A canadian health advisory panel says that Merck's arthritis drug Vioxx should be allowed to go on sale again in the country, 10 months after the company withdrew the blockbuster painkiller over reports that it increased the risk of heart disease.

11 Jul 2005

Over-the-counter painkillers more likely to cause heart attacks than banned drug Vioxx

Researchers in the UK are saying that some of the most commonly used painkillers are more likely to cause heart attacks than Vioxx, the arthritis drug withdrawn from the market last year after it was linked to heart disease.

12 Jun 2005

Survey highlights need for primary care guidance on NSAID use

New guidance on NSAID (non-steroidal anti-inflammatory drug) use is urgently needed to ensure the best patient care, European experts said today. The news coincides with the results from a European survey of 626 arthritis patients which found that many are confused and worried about the potential side-effects of their medication.

10 Jun 2005