Immune Response News and Research

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RBD-focused vaccines may offer broader protection against emerging COVID-19 variants

Published in The Lancet's eBioMedicine, 76 healthy adults from Melbourne, aged 18 to 64 who were previously vaccinated with licensed SARS-CoV-2 vaccines, were randomized to receive a fourth dose of a novel protein vaccine, mRNA vaccine or placebo.

12 Dec 2023

New study unlocks hope for immunotherapy in metastatic prostate cancer

Immunotherapy has been disappointing as a prostate cancer treatment, but a new Columbia study suggests that the powerful treatments have potential when the disease starts to spread.

12 Dec 2023

Evaluation of immunogenicity-induced DNA vaccines against different SARS-CoV-2 variants

Five DNA vaccine candidates based on different SARS-CoV-2 strains.

12 Dec 2023

Researchers discover next-gen lipid nanoparticles for muscle-focused mRNA delivery

A team of researchers based at the University of Toronto's (U of T) Leslie Dan Faculty of Pharmacy has discovered a novel ionizable lipid nanoparticle that enables muscle-focused mRNA delivery while minimizing off-target delivery to other tissues.

8 Dec 2023

Repeated mRNA vaccines supercharge immune response against COVID-19, study finds

Study published in Nature Immunology reveals that repeated mRNA COVID-19 vaccinations enhance immune response, especially in previously infected individuals, leading to a diversified and increased number of immune cell clones and a stronger ability to combat various virus strains.

7 Dec 2023

Liver trigger holds the key to boosting gene therapy success

Indiana University School of Medicine researchers have uncovered vital insights regarding a liver trigger that blocks an undesired immune response from gene therapy, surprisingly resulting in the activation of specific immune cells, despite the liver's typical role in suppressing immune responses.

7 Dec 2023

Immune system shows remarkable adaptability to SARS-CoV-2 variants

Although SARS-CoV-2 is no longer a stranger to the immune system, new virus variants still pose a challenge.

7 Dec 2023

Blocking an allergy pathway unleashes antitumor immunity in mouse models of non-small cell lung cancer

Researchers at the Icahn School of Medicine at Mount Sinai have identified an allergy pathway that, when blocked, unleashes antitumor immunity in mouse models of non-small cell lung cancer (NSCLC).

6 Dec 2023

Design modifications offer promise for safer and more effective mRNA therapeutics

Researchers have discovered that misreading of therapeutic mRNAs by the cell's decoding machinery can cause an unintended immune response in the body.

6 Dec 2023

Study links elevated BMI to weaker immune response post-SARS-CoV-2 infection

Researchers evaluated the impact of BMI elevation on humoral immunity levels against SARS-CoV-2.

6 Dec 2023

Novel mRNA vaccine GLB-COV2-043 shows high efficacy against COVID-19 variants in early trials

The safety, efficacy, and immunogenicity of a mRNA-based vaccine.

5 Dec 2023

Investigating IDO1 and PDL1: Key immune checkpoints in cutaneous leishmaniasis research

In this Interview News Med talks to Dr. Nidhi Dey about immune checkpoints IDO1 and PDL1 and how they relate to cutaneous leishmaniasis research.

From TissueGnostics 5 Dec 2023

Carrot juice boosts immune response, cuts inflammation, new study reveals

A study in the journal Nutrients by Danish researchers shows that consuming carrot juice, rich in falcarinol and falcarindiol, influences acute inflammatory mediators and innate immune responses in human blood.

4 Dec 2023

Leading public health groups urge high-risk patients to get flu shot

During National Influenza Vaccination Week (December 4-8, 2023), leading public health organizations are encouraging everyone to get a flu shot if they have not already done so.

4 Dec 2023

Common dietary supplement could protect against chronic Cryptosporidium infections

Researchers at the Francis Crick Institute have discovered that a common dietary supplement could protect against chronic Cryptosporidium infections which are particularly prevalent in children under two and in areas with poorer sanitation.

4 Dec 2023

Controlling high blood pressure may not be enough to prevent related cognitive declines, study finds

Researchers at Weill Cornell Medicine have found that controlling high blood pressure may not be enough to prevent associated cognitive declines.

4 Dec 2023

Overweight people may have impaired antibody response to COVID-19 infection

University of Queensland-led research shows being overweight can impair the body's antibody response to SARS-CoV-2 infection but not to the protection offered by vaccination.

4 Dec 2023

MU researchers unveil the immune system's secret weapon against lung cancer

As one of the most insidious diseases in the world, cancer has few treatments that work to eradicate it completely.

4 Dec 2023

Painless ultrasound vaccine delivery on the horizon

An estimated quarter of adults and two-thirds of children have strong fears around needles, according to the U.S. Centers for Disease Control and Prevention.

3 Dec 2023

Silencing galectin 1 protein shrinks liver cancer tumors in mice

Researchers at UC Davis Comprehensive Cancer Center have shown that inhibiting a specific protein using gene therapy can shrink hepatocellular carcinoma (HCC) in mice.

30 Nov 2023

Immune Response News and Research

RBD-focused vaccines may offer broader protection against emerging COVID-19 variants

New study unlocks hope for immunotherapy in metastatic prostate cancer

Evaluation of immunogenicity-induced DNA vaccines against different SARS-CoV-2 variants

Researchers discover next-gen lipid nanoparticles for muscle-focused mRNA delivery

Repeated mRNA vaccines supercharge immune response against COVID-19, study finds

Liver trigger holds the key to boosting gene therapy success

Immune system shows remarkable adaptability to SARS-CoV-2 variants

Blocking an allergy pathway unleashes antitumor immunity in mouse models of non-small cell lung cancer

Design modifications offer promise for safer and more effective mRNA therapeutics

Study links elevated BMI to weaker immune response post-SARS-CoV-2 infection

Novel mRNA vaccine GLB-COV2-043 shows high efficacy against COVID-19 variants in early trials

Investigating IDO1 and PDL1: Key immune checkpoints in cutaneous leishmaniasis research

Carrot juice boosts immune response, cuts inflammation, new study reveals

Leading public health groups urge high-risk patients to get flu shot

Common dietary supplement could protect against chronic Cryptosporidium infections

Controlling high blood pressure may not be enough to prevent related cognitive declines, study finds

Overweight people may have impaired antibody response to COVID-19 infection

MU researchers unveil the immune system's secret weapon against lung cancer

Painless ultrasound vaccine delivery on the horizon

Silencing galectin 1 protein shrinks liver cancer tumors in mice

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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