Immune Response News and Research

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Hormone levels tied to metabolic health in obesity

Researchers investigate the relationship between obesity types and serum leptin (LEP) and adiponectin (ADP) levels, shedding light on metabolic differences in various obesity phenotypes. Their findings highlight correlations between adipokines, glucose utilization, lipid metabolism, and obesity-related metabolic disorders.

22 Oct 2023

Scientists uncover a group of immune cells that may drive severe asthma in older men

Scientists from La Jolla Institute for Immunology (LJI) and The University of Southampton, UK, have uncovered a group of immune cells that may drive severe asthma.

20 Oct 2023

Linking perinatal events to juvenile idiopathic arthritis-uveitis

Researchers investigate perinatal events associated with the manifestation of juvenile idiopathic arthritis and the development of JIA-uveitis.

20 Oct 2023

Low serotonin levels observed in long COVID and other viral infections

Researchers identify a pathophysiological mechanism linking serotonin reduction to the multifaceted etiology of post-acute sequelae of COVID-19.

20 Oct 2023

"Two-for-one" cancer immunotherapy more effective and at least as safe as standard treatments

A "two-for-one" cancer immunotherapy is potentially more effective and at least as safe as standard immunotherapies, physician-scientists from UPMC Hillman Cancer Center who led an international, early-phase clinical trial report today in the journal Nature Medicine.

19 Oct 2023

Chan Zuckerberg Initiative launches new biomedical research hub to build technologies for improving health

Today, the Chan Zuckerberg Initiative (CZI) announced the launch of a new biomedical research hub in New York City that will catalyze collaboration between leading scientific and technology institutions in the area, with the goal of solving grand scientific challenges on 10- to 15-year time horizons.

18 Oct 2023

“Goblet cells” play an important role in the development of allergic conjunctivitis

The first step in the development of the allergic conjunctivitis is the penetration of the allergen through the epithelial layer.

17 Oct 2023

Promising breakthroughs ignite hope for a novel and effective Tuberculosis vaccine

The success and challenges of developing different tuberculosis (TB) vaccine types.

17 Oct 2023

Study reveals previously unappreciated role for innate immune cells in early stages of TB infection

A new study from the University of Pittsburgh Center for Vaccine Research published today in the Journal of Experimental Medicine describes a previously unappreciated role for a class of immune cells in the early stages of tuberculosis (TB) infection.

16 Oct 2023

Live vaccinations found to be safe for pediatric organ transplant recipients

Live vaccinations provided to children who previously received liver or kidney transplants were found to be safe and prompted an immune response to guard against several life-threatening conditions, according to a new study published Oct. 12, 2023, in JAMA Network Open.

16 Oct 2023

New mRNA flu vaccine shows promise: Faster to produce, highly effective in mice

The study evaluates the efficacy of a new quadrivalent mRNA influenza vaccine, finding it to be highly immunogenic and protective in a mouse model. Compared to traditional vaccines, the mRNA-based option offers advantages like reduced production time and elimination of the risk of growth-promoting mutations.

15 Oct 2023

Are people with HIV at a higher risk of severe COVID-19 outcomes?

The research review indicates that people with HIV, especially those with low CD4 cell counts, face greater risks of severe COVID-19 outcomes and have suboptimal immune responses to SARS-CoV-2. Antiretroviral therapy aids in clearing infections, and a third vaccine dose reduces the risk of breakthrough infections among this population.

15 Oct 2023

Newly discovered synthetic adjuvant materials could make vaccines more accessible, sustainable

New raw vaccine materials that could make vaccines more accessible, sustainable, and ethical have been discovered.

14 Oct 2023

Strong antibody response and nasal cytokines may protect young children from severe COVID-19

New research helps explain why young children have lower rates of severe COVID-19 than adults. A study of infants and young children found those who acquired SARS-CoV-2 had a strong, sustained antibody response to the virus and high levels of inflammatory proteins in the nose but not in the blood.

13 Oct 2023

Scientists discover feedback loop that controls itch and inflammation

It can be a relief to scratch the occasional itch, but when itch gets out of control, it can become a serious health problem. How does the body know when to stop?

13 Oct 2023

New study finds host strategy to cope with sleeping sickness

A new study led by Luísa Figueiredo, group leader at the Instituto de Medicina Molecular João Lobo Antunes (iMM; Portugal), and published today in the scientific journal Nature Microbiology found a new strategy by the host to cope with Trypanosoma brucei infection.

12 Oct 2023

Beyond the gut: Crohn's disease's oral clues for timely diagnosis

The oral manifestations of CD.

12 Oct 2023

Maternal pertussis vaccination boosts infant protection up to eight months

In a large-scale Australian study, maternal vaccination during pregnancy significantly increased pertussis resistance in infants up to eight months. While it slightly reduced the effectiveness of infants' routine vaccinations, it did not increase infection risk.

11 Oct 2023

Study sheds light on how the immune system differentiates between self and non-self antigens

A groundbreaking study, led by Professor Kyemyung Park and his research team in the Graduate School of Health Science and Technology and the Department of Biomedical Engineering at UNIST has shed light on the intricate mechanism behind the immune system's ability to differentiate between self and non-self antigens.

11 Oct 2023

Pitt scientists develop new approach to reduce side effects of organ transplants

Giving living donor liver transplant recipients an infusion of immune cells derived from their donor a week before transplantation is feasible, safe – and may lead to recipients being successfully weaned off immunosuppressant medications without rejecting the transplanted organ.

11 Oct 2023

Immune Response News and Research

Hormone levels tied to metabolic health in obesity

Scientists uncover a group of immune cells that may drive severe asthma in older men

Linking perinatal events to juvenile idiopathic arthritis-uveitis

Low serotonin levels observed in long COVID and other viral infections

"Two-for-one" cancer immunotherapy more effective and at least as safe as standard treatments

Chan Zuckerberg Initiative launches new biomedical research hub to build technologies for improving health

“Goblet cells” play an important role in the development of allergic conjunctivitis

Promising breakthroughs ignite hope for a novel and effective Tuberculosis vaccine

Study reveals previously unappreciated role for innate immune cells in early stages of TB infection

Live vaccinations found to be safe for pediatric organ transplant recipients

New mRNA flu vaccine shows promise: Faster to produce, highly effective in mice

Are people with HIV at a higher risk of severe COVID-19 outcomes?

Newly discovered synthetic adjuvant materials could make vaccines more accessible, sustainable

Strong antibody response and nasal cytokines may protect young children from severe COVID-19

Scientists discover feedback loop that controls itch and inflammation

New study finds host strategy to cope with sleeping sickness

Beyond the gut: Crohn's disease's oral clues for timely diagnosis

Maternal pertussis vaccination boosts infant protection up to eight months

Study sheds light on how the immune system differentiates between self and non-self antigens

Pitt scientists develop new approach to reduce side effects of organ transplants

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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