Immune Response News and Research

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Cohort Review Committee evaluates SCIB1 dose escalation, safety in Phase 1 trial

Scancell Holdings Plc, the developer of therapeutic cancer vaccines, is pleased to announce that the first group of patients receiving the lowest dose of SCIB1 in the Phase I clinical trial has been evaluated by the Cohort Review Committee.

31 Jan 2011

Preclinical data on Inovio’s intradermal electroporation delivery devices presented at Phacilitate Vaccine Forum

Inovio Pharmaceuticals, Inc., a leader in the development of novel therapeutic and preventive vaccines against cancers and infectious diseases, announced today the presentation of recent preclinical data using its next generation of minimally invasive intradermal (skin) electroporation delivery devices at the Phacilitate Vaccine Forum 2011 in Washington, DC.

28 Jan 2011

Triggering CD45 molecule blocks early development of AD

A new target for the prevention of adverse immune responses identified as factors in the development of Alzheimer's disease (AD) has been discovered by researchers at the University of South Florida's Department of Psychiatry and the Center of Excellence for Aging and Brain Repair.

27 Jan 2011

Research shows how pathogenic bacteria hide inside host cells

A new study into Staphylococcus aureus, the bacterium which is responsible for severe chronic infections worldwide, reveals how bacteria have developed a strategy of hiding within host cells to escape the immune system as well as many antibacterial treatments. The research, published by EMBO Molecular Medicine, demonstrates how ‘phenotype switching’ enables bacteria to adapt to their environmental conditions, lie dormant inside host cells and become a reservoir for relapsing infections.

26 Jan 2011

Spine surgeon successfully treated with RNL Bio's stem cell therapy for Autoimmune Arthritis

RNL BIO CO., LTD, a leading biopharmaceutical company specialized in adult stem cell therapeutics, announced on January 21, 2011 another successful patient report utilizing stem cell therapy on a leading US orthopedic spine surgeon who suffered from Autoimmune Arthritis.

26 Jan 2011

Simple means of improving binding affinity of synbodies

Antibodies are watchdogs of human health, continuously prowling the body and registering minute changes associated with infection or disease with astonishing acuity. They also serve as biochemical memory banks, faithfully recording information about pathogens they encounter and efficiently storing this data for later use.

25 Jan 2011

Also in Global Health News: Cholera death in DR; TB vaccine study; Rising food prices

"Dominican Republic on Sunday confirmed that a 53-year-old Haitian man has become the country's first death from cholera and announced the immediate start of a broad disease control and monitoring operation" around the eastern town of Higuey where he was being treated and later died, Latin American Herald Tribune reports (1/24).

24 Jan 2011

CRI, Oncovir sign new investment agreement to produce immunological stimulant

Cancer Research Institute, a U.S. nonprofit organization founded in 1953 to advance the science of tumor immunology and foster the discovery and development of new cancer immunotherapies, announced today that its Cancer Vaccine Acceleration Fund, a joint initiative with the Ludwig Institute for Cancer Research, has completed a new investment agreement with Oncovir, a biotechnology company based in Washington, D.C., to enable the production of the immunological stimulant Hiltonol- (Poly-ICLC).

24 Jan 2011

Odontoblast cells are part of immune system, protect teeth from decay: New research

It is known that teeth can protect themselves, to some extent, from attack by bacteria but that inflammation within a tooth can be damaging and, in extreme cases, lead to abscess or death of the tooth. New research published in BioMed Central's open access journal BMC Immunology shows that odontoblast cells are part of the immune system and fight to protect teeth from decay.

23 Jan 2011

CVAF completes new investment agreement with Oncovir for production of Hiltonol

Cancer Research Institute, Inc. (CRI), a U.S. nonprofit organization founded in 1953 to advance the science of tumor immunology and foster the discovery and development of new cancer immunotherapies, announced today that its Cancer Vaccine Acceleration Fund (CVAF), a joint initiative with the Ludwig Institute for Cancer Research (LICR), has completed a new investment agreement with Oncovir, Inc., a biotechnology company based in Washington, D.C., to enable the production of the immunological stimulant Hiltonol® (Poly-ICLC).

21 Jan 2011

Researchers map complex choreography used by immune system's T cells to recognize pathogens

Researchers have for the first time mapped the complex choreography used by the immune system's T cells to recognize pathogens while avoiding attacks on the body's own cells.

21 Jan 2011

Vibrio cholerae kills E. coli bacteria

Just over a year after the earthquake in Haiti killed 222,000 people there's a new problem that is killing Haitians. A cholera outbreak has doctors in the area scrambling and the water-borne illness has already claimed 3600 lives according to officials with M-dicin Sans Fronti-res (Doctors without Borders).

21 Jan 2011

New research says EPO hormone can modulate immune response

New research reveals that a hormone best known for stimulating the production of red blood cells can modulate the immune response. The study, published by Cell Press in the January 27th issue of the journal Immunity, finds that erythropoietin has contrasting influences on infectious and inflammatory diseases and may be useful in the design of new therapeutic strategies.

21 Jan 2011

FDA grants Soligenix Orphan Drug Designation to RiVax for prevention of ricin intoxication

Soligenix, Inc., a late-stage biopharmaceutical company, announced today that the US Food and Drug Administration (FDA) has granted Orphan Drug Designation to RiVax™ for the prevention of ricin intoxication. RiVax™ is a proprietary vaccine that contains a recombinant subunit of the A chain of ricin toxin which induces ricin neutralizing antibodies in humans and animals.

20 Jan 2011

Malaria parasite caught in action on film for the first time

Australian researchers have managed to take pictures of microscopic malaria parasite as it invades a human red blood cell. This will provide a deeper understanding of the parasite’s behaviour and may help fight it. Up to 10% of the world’s population contract malaria every year and a million people, mostly pregnant women and children, die as a result of the parasite transmitted by infected mosquitoes.

19 Jan 2011

National Jewish Health issued method patent for desensitizing B cells

National Jewish Health has been issued a US patent claiming a method to desensitize B cells by inactivating antigen receptors on their surfaces. The method, discovered by John Cambier, PhD, Chairman of the Integrated Department of Immunology at National Jewish Health, holds promise for treatment of B-cell mediated diseases, such as lymphoma and leukemia, rheumatoid arthritis, lupus and rejection of organ transplants.

19 Jan 2011

Curcumin and dye brilliant blue G may help block dangerous swelling in TBI

An old Indian spice and a dye whose cousin makes sports drinks blue are pointing scientists toward better treatment of traumatic brain injuries.

19 Jan 2011

Michael Cuccione Foundation donates $5 million to support childhood cancer research

The Michael Cuccione Foundation is donating $5 million to support the childhood cancer research program at the Child & Family Research Institute at BC Children's Hospital, now named the Michael Cuccione Foundation Childhood Cancer Research Program. The gift, the largest ever to cancer research at BC Children's, was announced during an event at the research institute, where the program is based.

12 Jan 2011

Antibodies produced by people who recovered from H1N1 offer clues for universal flu vaccine

The antibodies produced by individuals who fought off H1N1 (swine flu) infection last year may bring researchers one step closer to their quest to develop a "universal" flu vaccine, U.S. researchers said Monday, HealthDay News/Bloomberg Businessweek reports.

12 Jan 2011

Vaccines for alcoholism and cocaine addiction coming soon

In a latest development, researchers from Chile have come up with a vaccine to cure alcoholics. It will help them kick the habit by creating a sensation of a terrible hangover after just a few drinks. The mechanism by which this vaccine acts is by neutralizing a group of enzymes that help the body to break down alcohol. When the enzymes aldehyde dehydrogenase is disabled the body accumulates the alcohol to create the hangovers after just a few drinks.

9 Jan 2011

Immune Response News and Research

Cohort Review Committee evaluates SCIB1 dose escalation, safety in Phase 1 trial

Preclinical data on Inovio’s intradermal electroporation delivery devices presented at Phacilitate Vaccine Forum

Triggering CD45 molecule blocks early development of AD

Research shows how pathogenic bacteria hide inside host cells

Spine surgeon successfully treated with RNL Bio's stem cell therapy for Autoimmune Arthritis

Simple means of improving binding affinity of synbodies

Also in Global Health News: Cholera death in DR; TB vaccine study; Rising food prices

CRI, Oncovir sign new investment agreement to produce immunological stimulant

Odontoblast cells are part of immune system, protect teeth from decay: New research

CVAF completes new investment agreement with Oncovir for production of Hiltonol

Researchers map complex choreography used by immune system's T cells to recognize pathogens

Vibrio cholerae kills E. coli bacteria

New research says EPO hormone can modulate immune response

FDA grants Soligenix Orphan Drug Designation to RiVax for prevention of ricin intoxication

Malaria parasite caught in action on film for the first time

National Jewish Health issued method patent for desensitizing B cells

Curcumin and dye brilliant blue G may help block dangerous swelling in TBI

Michael Cuccione Foundation donates $5 million to support childhood cancer research

Antibodies produced by people who recovered from H1N1 offer clues for universal flu vaccine

Vaccines for alcoholism and cocaine addiction coming soon

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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