Immune Response News and Research

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Persistent tumor mutation burden linked with therapeutic response to immunotherapy

Cancer experts have tried, sometimes unsuccessfully, to use the total number of mutations in a tumor, called the tumor mutation burden (TMB), to predict a patient's response to immunotherapy.

26 Jan 2023

Atomic-level computer model of the H1N1 virus reveals new vulnerabilities

According to the World Health Organization, each year there are an estimated 1 billion cases of influenza, between 3-5 million severe cases and up to 650,000 influenza-related respiratory deaths globally.

25 Jan 2023

F-box gene mediates dietary restriction effects on extending the health span of C. elegans

A new research paper was published in Aging (listed as "Aging (Albany NY)" by MEDLINE/PubMed and "Aging-US" by Web of Science) Volume 15, Issue 1, entitled, "The innate immune signaling component FBXC-58 mediates dietary restriction effects on healthy aging in Caenorhabditis elegans."

25 Jan 2023

Maternal and perinatal outcomes of women infected with SARS-CoV-2 during the Omicron wave in Italy

Researchers assessed the impact of SARS-CoV-2 vaccination on pregnant women during the Omicron wave.

25 Jan 2023

Single drop of blood can be used to measure thousands of molecules

Researchers at Stanford Medicine have shown they can measure thousands of molecules — some of which are signals of health — from a single drop of blood.

25 Jan 2023

Targeting newly discovered signaling pathway could boost the potency of cancer therapeutics

Cells zealously protect the integrity of their genomes, because damage can lead to cancer or cell death. The genome -; a cell's complete set of DNA -; is most vulnerable while it is being duplicated before a cell divides. Cancer cells constantly are dividing, so their genomes are constantly in jeopardy.

24 Jan 2023

Mosaic RBD nanoparticles offer 100% protection against SARS-CoV-2 in animal model

A recent PNAS journal study has sought to address the above-stated drawback and developed a new strategy that involves a self-assembling scaffold of proliferating cell nuclear antigen (PCNA). This technique can develop nanoparticles containing evenly incorporated heterotypic antigens.

24 Jan 2023

Scientists demonstrate how microbiome and feeding patterns impact circadian rhythms in the gut

A study published in the journal PNAS reveals that the gut microbiome stabilizes the synchronization between gut and brain circadian rhythms.

24 Jan 2023

Insufficient sleep during the teenage years may increase subsequent risk of multiple sclerosis

Insufficient and disturbed sleep during the teenage years may heighten the subsequent risk of multiple sclerosis (MS), suggests a case-control study published online in the Journal of Neurology Neurosurgery & Psychiatry.

24 Jan 2023

Modulating the lipid composition to treat bronchial asthma

Bronchial asthma, a chronic inflammatory disease of the airways that is reversible in certain cases, usually presents with cough, difficulty of breathing, and wheezing.

24 Jan 2023

Study analyzes how immunological memory gets generated and maintained

Scientists have long sought to better understand the human body's immune responses that occur during various diseases, including cancer and inflammatory diseases.

23 Jan 2023

Mutations may underlie how the most aggressive lymphomas arise and resist therapies

The key to understanding how the most aggressive lymphomas arise and resist current therapies may lie in mutations that disrupt a critical natural selection process among antibody-producing B cells, according to a multi-institutional preclinical study led by Weill Cornell Medicine investigators.

19 Jan 2023

Wistar scientists receive $397,663 to explore the ability of natural killer cells to kill HIV-infected cells

amfAR, The Foundation for AIDS Research, has awarded Luis J. Montaner, D.V.M., D.Phil., in collaboration with Mohamed Abdel-Mohsen, Ph.D., a Target Grant for $397,663 over two years. Montaner, who leads The Wistar Institute's HIV Research Program, is studying the ability of a type of immune cell known as natural killer (NK) cells to kill HIV-infected cells.

19 Jan 2023

Schizophrenia may be linked with vascular alterations in the brain, study suggests

A study conducted in Brazil and reported in an article published in Molecular Psychiatry suggests that schizophrenia may be associated with alterations in the vascularization of certain brain regions.

19 Jan 2023

MedUni Vienna researchers identify specific immune response to Epstein-Barr virus

Medical science has not yet been able to explain why the Epstein-Barr virus triggers infectious mononucleosis (IM) in some people with initial infections and not in others.

19 Jan 2023

Researchers find that study results converge on a consistent relationship between antibody levels and protection from COVID-19

Researchers described the factors associated with protection, protection thresholds, and immunobridging in COVID-19 patients.

19 Jan 2023

Epitope mapping reveals the humoral responses against the main SARS-CoV-2 structural proteins in infected patients from Africa

Researchers performed immunoglobulin (Ig)M and IgG epitope mapping against 487 SARS-CoV-2 peptides.

18 Jan 2023

Immune Response News and Research

Persistent tumor mutation burden linked with therapeutic response to immunotherapy

Atomic-level computer model of the H1N1 virus reveals new vulnerabilities

F-box gene mediates dietary restriction effects on extending the health span of C. elegans

Maternal and perinatal outcomes of women infected with SARS-CoV-2 during the Omicron wave in Italy

Single drop of blood can be used to measure thousands of molecules

Targeting newly discovered signaling pathway could boost the potency of cancer therapeutics

Mosaic RBD nanoparticles offer 100% protection against SARS-CoV-2 in animal model

Scientists demonstrate how microbiome and feeding patterns impact circadian rhythms in the gut

Insufficient sleep during the teenage years may increase subsequent risk of multiple sclerosis

Modulating the lipid composition to treat bronchial asthma

Study analyzes how immunological memory gets generated and maintained

Mutations may underlie how the most aggressive lymphomas arise and resist therapies

Wistar scientists receive $397,663 to explore the ability of natural killer cells to kill HIV-infected cells

Schizophrenia may be linked with vascular alterations in the brain, study suggests

MedUni Vienna researchers identify specific immune response to Epstein-Barr virus

Researchers find that study results converge on a consistent relationship between antibody levels and protection from COVID-19

Epitope mapping reveals the humoral responses against the main SARS-CoV-2 structural proteins in infected patients from Africa

Study sheds new light on how the B cell academy mounts a diverse immune response

The diverse mechanisms by which galectins can regulate adaptive and innate immune responses

Upregulation of Robo4 expression reduces mortality from severe infection

Hasret Altan-Martin

Speeding Up Sample Preparation to Accelerate Analytical Chemistry

Ask the Expert: 7 Questions about Colorectal Cancer & Non-invasive Fecal DNA Testing

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