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Human breast cell atlas unveils early changes in BRCA gene mutation carriers

Researchers at the University of Cambridge have created the world's largest catalog of human breast cells, which has revealed early cell changes in healthy carriers of BRCA1 and BRCA2 gene mutations.

28 Mar 2024

Predicting treatment response in common blood cancer with DNA methylation profiling

A recent study led by Dr. Manel Esteller, Director of the Josep Carreras Institute, shows how DNA methylation profiling in a common type of blood cancer, myelodysplastic syndrome, predicts whether the patient will respond to treatment.

28 Mar 2024

Clinical trial to test the feasibility of using at-home cancer immunotherapy

A clinical trial from Keck Medicine of USC will test the feasibility of treating non-small cell lung cancer with immunotherapy provided at home.

28 Mar 2024

Longer durations of breastfeeding lowers the risk of childhood cancers

Whether duration of breastfeeding was associated with a lower risk of childhood cancers.

28 Mar 2024

Drug combination could hold new promise for treating colorectal cancers and other solid tumors

A pair of medications that make malignant cells act as if they have a virus could hold new promise for treating colorectal cancers and other solid tumors, reports a study published today in Science Advances.

27 Mar 2024

MMR vaccine slashes antibiotic use in toddlers: Nordic study shines light on broader benefits

Study demonstrates that administering the MMR vaccine to children under two, following three DTaP doses, significantly reduces the need for antibiotic treatments, highlighting potential non-specific protective effects.

26 Mar 2024

Breakthrough study offers hope for an effective HIV cure

By 2030, the World Health Organization (WHO), the Global Fund and UNAIDS are hoping to end the human immunodeficiency virus (HIV) and AIDS epidemic.

26 Mar 2024

Researchers identify viable vaccine targets for hepatitis C infections

By studying individuals who spontaneously clear hepatitis C infections, a team of researchers has identified viable vaccine targets for a disease that infects 70 million worldwide with case numbers increasing every year.

26 Mar 2024

Statins show promise in reducing gum disease inflammation

Could taking statins benefit your mouth in addition to your arteries? A new study conducted in cell cultures showed that cholesterol-lowering drugs help to dampen the inflammation associated with periodontal disease by altering the behavior of macrophages, a type of immune cell.

25 Mar 2024

Leveraging cancer therapies to combat tuberculosis

What could cancer teach us about tuberculosis? That's a question Meenal Datta has been chasing since she was a graduate student.

25 Mar 2024

Children with multiple sclerosis have better outcomes if treated early and with high-efficacy therapies

A ground-breaking study – the largest of its kind globally – has found children with multiple sclerosis (MS) have better outcomes if treated early and with the same high-efficacy therapies as adults.

25 Mar 2024

ANU scientists uncover gene mutation driving psoriasis and psoriatic arthritis

Scientists from The Australian National University (ANU) have discovered a gene mutation is responsible for causing psoriasis – a chronic inflammatory skin disease that causes patients to develop red, scaly and itchy patches across their body.

25 Mar 2024

Study shows cellular, molecular overlaps in ALS and FTLD

On the surface, the movement disorder amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, and the cognitive disorder frontotemporal lobar degeneration (FTLD), which underlies frontotemporal dementia, manifest in very different ways. In addition, they are known to primarily affect very different regions of the brain.

22 Mar 2024