Immune System News and Research

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African Americans with SLE have higher antibody response to influenza vaccination: Study

New research shows that African Americans with systemic lupus erythematosus had a higher antibody response to influenza vaccination than European American patients.

21 May 2011

Indian wild plants offer hope against resistant infections

Cancer treatments often have the side effect of impairing the patient's immune system. This can result in life-threatening secondary infections from bacteria and fungi, especially since bacteria, like Staphylococcus aureus, are becoming multi-drug resistant.

20 May 2011

Osteoarthritis directly linked to low-fat, high-carb food

Osteoarthritis is a degenerative joint disease and the most common cause of disability today. It was once considered a problem of the old but it is now commonly diagnosed in those as young as the mid-twenties and early thirties. According to the Arthritis Foundation, about four million, quality-adjusted life years are lost due to knee osteoarthritis alone.

20 May 2011

Naltrexone improves clinical, inflammatory activity in Crohn's disease patients

Naltrexone reduced inflammation in Crohn's patients in a research study at Penn State College of Medicine.

20 May 2011

VBL to present positive VB-111 preclinical data in metastatic lung cancer at 14th ASGCT

VBL Therapeutics, a clinical-stage biotechnology company committed to the development of novel treatments for immune-inflammatory diseases and cancer, today announced that it will present preclinical data demonstrating VB-111's potential synergy and additive therapeutic effect when administered in combination with the conventional chemotherapy cancer treatments.

20 May 2011

VIDAS TOXO IgG Avidity assay to test for recent Toxoplasma gondii infection receives FDA clearance

On May 18, the U.S. Food and Drug Administration cleared the first test to help determine whether a pregnant woman or a person with swollen lymph nodes testing positive for toxoplasmosis, sometimes known as cat scratch disease, developed the infection within the past four months.

20 May 2011

CSL-Behring recombinant factor research presented

Advances that CSL Behring is making in developing innovative new technologies to meet the unmet therapeutic needs of patients with hemophilia A and B will be the topic of an oral presentation at an international medical congress on May 22, 2011. CSL Behring is a global biotherapeutics company specializing in plasma-derived and recombinant therapies and is a subsidiary of CSL Limited (ASX:CSL).

19 May 2011

ISCO enrolls first U.S.-based donor to establish clinical-grade human parthenogenetic stem cell bank

International Stem Cell Corporation has now enrolled the first U.S.-based donor in its program to establish a bank of clinical-grade human parthenogenetic stem cells (hpSCs) capable of being immune-matched to millions of patients.

19 May 2011

Advantagene reaches SPA agreement with FDA for ProstAtak Phase 3 trial to prevent prostate cancer recurrence

Advantagene, Inc., a Massachusetts-based biopharmaceutical company, announced today that it reached an agreement with the U.S. Food and Drug Administration on a Special Protocol Assessment (SPA) for a pivotal Phase 3 clinical trial of ProstAtak™, its lead agent for patients with newly diagnosed prostate cancer.

19 May 2011

New technique offers successful bone marrow, organ transplant for patients with autoimmune diseases

University of Minnesota Medical School researchers have discovered a method to quickly and exponentially grow regulatory T-cells - also known as "suppressor cells." The new process enables replication of the cells by tens of millions in several weeks, a dramatic increase over previous duplication methods. Historically, regulatory T-cells have been difficult to replicate.

19 May 2011

Humanized BLT mice help prevent HIV/AIDS transmission

The more than 2.7 million new HIV infections recorded per year leave little doubt that the HIV/AIDS epidemic continues to spread globally. That's why there's the need for safe, inexpensive and effective drugs to successfully block HIV transmission.

19 May 2011

Simple lymphocyte count effectively identifies prognosis of renal cell carcinoma

Each year, kidney cancer is diagnosed in nearly 60,000 people in the U.S. Many of these patients undergo surgery to remove the affected kidney, but this procedure can be risky for the elderly and those who have other health problems. Unfortunately, the prognosis of kidney cancer patients often cannot be determined until tumor samples are surgically removed and evaluated.

19 May 2011

Alemtuzumab as effective as other more expensive immune suppressants for kidney transplants

In the first head-to-head comparison of the three most common drugs used at the time of a kidney transplant to prevent organ rejection, researchers found that the least expensive drug - at one-half to one-fifth the price - is as safe and effective as the other two, according to a paper published by University of Alabama at Birmingham researchers in the May 19, 2011, issue of the New England Journal of Medicine.

19 May 2011

Children exposed to maternal smoking in utero have increased DNA methylation in AXL gene

Children whose mothers or grandmothers smoked during pregnancy are at increased risk of asthma in childhood, but the underlying causes of this are not well understood. Now a new study indicates changes in a process called DNA methylation that occurs before birth may be a root cause.

19 May 2011

Serpin-2 molecule may be a perfect target for preventing mosquito's immunity

Mosquitoes are becoming more resistant to current pesticides. That's troubling to Kansas State University biologist Kristin Michel, as it means malaria and other mosquito-borne diseases will continue spreading. A recent grant from the National Institutes of Health may change all that.

18 May 2011

Early childhood food allergies increase risk of severe allergy-related conditions and asthma later in life

Early results from the largest cross-sectional national allergy study ever conducted, to be released later this month, demonstrate that food allergies commonly occur in infants and toddlers, while environmental allergies, such as to dust, ragweed and mold, are more common in older children and adults.

From Quest Diagnostics 18 May 2011

Improved tissue grafts promote vascular growth in wound sites

Victims of third-degree burns and other traumatic injuries endure pain, disfigurement, invasive surgeries and a long time waiting for skin to grow back. Improved tissue grafts designed by Cornell scientists that promote vascular growth could hasten healing, encourage healthy skin to invade the wounded area and reduce the need for surgeries.

18 May 2011

CITN selects Cytheris' CYT107 for initial clinical trials at network institutions

Cytheris SA and the Cancer Immunotherapy Trials Network, a new initiative in immunotherapy funded by the National Cancer Institute with its Central Operations and Statistical Center headquartered at Fred Hutchinson Cancer Research Center, Seattle, Washington, today announced the selection of recombinant human interleukin-7, the investigational multifunctional cytokine under development by Cytheris, as one of the first immunotherapeutic agents proposed for initial clinical trials at network institutions.

18 May 2011

Cellular 'mechanic' keeps DNA damage in check in cells

CANCER RESEARCH UK scientists have discovered how a protein in immune cells plays an essential role in their development by repairing DNA damage - and if this protein is missing lymphomas can form.

17 May 2011

New avenue for treating breast cancer

Researchers at the CHUM Research Centre and the Peter MacCallum Cancer Centre in Australia have identified a new avenue for treating breast cancer.

17 May 2011

Immune System News and Research

African Americans with SLE have higher antibody response to influenza vaccination: Study

Indian wild plants offer hope against resistant infections

Osteoarthritis directly linked to low-fat, high-carb food

Naltrexone improves clinical, inflammatory activity in Crohn's disease patients

VBL to present positive VB-111 preclinical data in metastatic lung cancer at 14th ASGCT

VIDAS TOXO IgG Avidity assay to test for recent Toxoplasma gondii infection receives FDA clearance

CSL-Behring recombinant factor research presented

ISCO enrolls first U.S.-based donor to establish clinical-grade human parthenogenetic stem cell bank

Advantagene reaches SPA agreement with FDA for ProstAtak Phase 3 trial to prevent prostate cancer recurrence

New technique offers successful bone marrow, organ transplant for patients with autoimmune diseases

Humanized BLT mice help prevent HIV/AIDS transmission

Simple lymphocyte count effectively identifies prognosis of renal cell carcinoma

Alemtuzumab as effective as other more expensive immune suppressants for kidney transplants

Children exposed to maternal smoking in utero have increased DNA methylation in AXL gene

Serpin-2 molecule may be a perfect target for preventing mosquito's immunity

Early childhood food allergies increase risk of severe allergy-related conditions and asthma later in life

Improved tissue grafts promote vascular growth in wound sites

CITN selects Cytheris' CYT107 for initial clinical trials at network institutions

Cellular 'mechanic' keeps DNA damage in check in cells

New avenue for treating breast cancer

Immunology eBook

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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