Immunodeficiency News and Research

RSS

Immunodeficiency (or immune deficiency) is a state in which the immune system's ability to fight infectious disease is compromised or entirely absent.

Rise in US congenital syphilis cases linked to testing and treatment failures, CDC reports

An analysis in the Morbidity and Mortality Weekly Report highlights the surge in congenital syphilis cases in the US due to gaps in testing and treatment, underscoring the need for enhanced prenatal care strategies to combat this preventable disease effectively.

8 Nov 2023

Proof-of-concept study holds promise for safer gene therapy techniques for treating immunodeficiencies

Researchers described an approach to edit the recombination-activating gene 2 (RAG2) locus for therapeutic applications.

1 Nov 2023

SARS-CoV-2 antigens stick around: Study finds virus markers can linger for over a year

Researchers found that SARS-CoV-2 antigens can persist in the body for up to 14 months after initial infection, challenging the idea that COVID-19 is a transient illness. This finding has implications for understanding long-term effects of the virus and could influence future treatments and vaccines.

30 Oct 2023

Current jargon on antibiotic resistance fails to stick or scare, study finds

Researchers find that current terminology related to antimicrobial resistance (AMR) fails to effectively communicate the risks to the public. The study reveals that terms like "AMR" and "antimicrobial resistance" are poorly remembered and do not evoke sufficient risk perception, highlighting the need for improved public health messaging.

29 Oct 2023

Novel replacement strategy holds promise for the treatment of various genetic disorders

Severe Combined Immunodeficiencies (SCIDs) are a group of debilitating primary immunodeficiency disorders, primarily caused by genetic mutations that disrupt T-cell development. SCID can also affect B-cell and natural killer cell function and counts.

27 Oct 2023

Promising breakthroughs ignite hope for a novel and effective Tuberculosis vaccine

The success and challenges of developing different tuberculosis (TB) vaccine types.

17 Oct 2023

Are people with HIV at a higher risk of severe COVID-19 outcomes?

The research review indicates that people with HIV, especially those with low CD4 cell counts, face greater risks of severe COVID-19 outcomes and have suboptimal immune responses to SARS-CoV-2. Antiretroviral therapy aids in clearing infections, and a third vaccine dose reduces the risk of breakthrough infections among this population.

15 Oct 2023

IL-17: The molecule that could revolutionize autoimmune and cancer treatments

The research paper explores the multifaceted role of the IL-17 family in immune response, covering everything from infection control to pathological conditions like autoimmune diseases and cancer. Future therapies may exploit IL-17's unique signaling pathways to offer more targeted and cost-effective treatments.

12 Oct 2023

EVScape: New tool to forecast which SARS-CoV-2 variants could dodge our immunity

Researchers have developed EVScape, a predictive tool that identifies which SARS-CoV-2 strains are most likely to evade host immunity. Utilizing a deep generative model and structural information, the tool offers early warning about viral variants, aiding in the timely development of effective vaccines and treatments.

12 Oct 2023

Unlocking hope: Promising treatments for cognitive impairment in HIV patients on the horizon

Researchers examine the mechanisms responsible for the increased risk of neurocognitive impairment in HIV patients and explore potential treatments.

12 Oct 2023

New TB vaccination strategy could save hundreds of thousands of lives with HIV

Scientists at the University of Pittsburgh School of Medicine have discovered a tuberculosis (TB) vaccination strategy that could prevent the leading cause of death among people worldwide living with HIV.

10 Oct 2023

Saliva test breakthrough: Early detection for ectopic pregnancies on the horizon

Salivary proteins may offer early detection for ectopic pregnancies, potentially saving maternal lives through a non-invasive diagnostic approach. The study identifies specific proteins that are prominently present in ruptured ectopic pregnancy cases, highlighting the potential for developing a saliva-based diagnostic kit.

9 Oct 2023

Amsterdam's H-TEAM initiative on track to eradicate HIV with groundbreaking city-centered approach

Amsterdam's H-TEAM initiative has achieved a significant reduction in HIV infections from 2010 to 2022 using a city-centered approach. By combining treatments, including testing, pre-exposure prophylaxis, and stakeholder collaboration, the city has surpassed the UNAIDS 95-95-95 target and is on track to potentially eliminate HIV entirely in the near future.

9 Oct 2023

New insights into how neutrophils fight Candida albicans infection

Umeå University researchers, Sweden, unveil how the most common white blood cells, neutrophils, counter Candida albicans toxin stopping its tracks.

5 Oct 2023

Could seaweeds be the superfood and medicine of the future?

Researchers consolidate the diverse nutritional and medicinal benefits of seaweeds, touting their potential in food, nutraceuticals, and pharmaceuticals. The study also highlights challenges and opportunities in industrial applications, calling for more research to optimize extraction and refinement processes.

2 Oct 2023

One health wake-up call: London's river data highlights environmental perils

The largest-ever spatiotemporal monitoring of chemicals/contaminants of emerging concern (CECs) in London waterways.

26 Sep 2023

Unlocking the power of mRNA vaccines: From COVID-19 to cancer and beyond

A comprehensive review in Signal Transduction and Targeted Therapy delves into the versatility and effectiveness of mRNA vaccines, from their game-changing role in COVID-19 to potential applications in cancer and rare diseases. Despite drawbacks like stability and high immunogenicity, advancements in vaccine technology have poised mRNA platforms as a robust tool for both preventive and therapeutic interventions.

21 Sep 2023

Cracking syphilis code: Genome sequencing reveals transmission secrets

Using whole genome sequencing, a new Lancet Microbe study sheds light on syphilis transmission dynamics in England. The research identifies distinct transmission clusters, revealing the effectiveness of genomic data in tracking and intervening in syphilis outbreaks.

20 Sep 2023

New immunoregulatory protein linked to autoimmune disease

Autoimmune diseases are complex illnesses, the causes of which are diverse and have not yet been fully explained.

18 Sep 2023

Unlocking the power of lectins: BOA emerges as a potent weapon against all SARS-CoV-2 variants

Researchers discover that antiviral lectins like BOA can effectively inhibit SARS-CoV-2 and its variants by targeting spike glycans, opening doors for potential pan-coronavirus treatments. The study reveals that BOA's multivalent interactions make it a potent inhibitor against a range of viral variants, offering promise for future therapeutic strategies.

14 Sep 2023

Immunodeficiency News and Research

Further Reading

Rise in US congenital syphilis cases linked to testing and treatment failures, CDC reports

Proof-of-concept study holds promise for safer gene therapy techniques for treating immunodeficiencies

SARS-CoV-2 antigens stick around: Study finds virus markers can linger for over a year

Current jargon on antibiotic resistance fails to stick or scare, study finds

Novel replacement strategy holds promise for the treatment of various genetic disorders

Promising breakthroughs ignite hope for a novel and effective Tuberculosis vaccine

Are people with HIV at a higher risk of severe COVID-19 outcomes?

IL-17: The molecule that could revolutionize autoimmune and cancer treatments

EVScape: New tool to forecast which SARS-CoV-2 variants could dodge our immunity

Unlocking hope: Promising treatments for cognitive impairment in HIV patients on the horizon

New TB vaccination strategy could save hundreds of thousands of lives with HIV

Saliva test breakthrough: Early detection for ectopic pregnancies on the horizon

Amsterdam's H-TEAM initiative on track to eradicate HIV with groundbreaking city-centered approach

New insights into how neutrophils fight Candida albicans infection

Could seaweeds be the superfood and medicine of the future?

One health wake-up call: London's river data highlights environmental perils

Unlocking the power of mRNA vaccines: From COVID-19 to cancer and beyond

Cracking syphilis code: Genome sequencing reveals transmission secrets

New immunoregulatory protein linked to autoimmune disease

Unlocking the power of lectins: BOA emerges as a potent weapon against all SARS-CoV-2 variants

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

Latest News