Immunodeficiency News and Research

RSS

Immunodeficiency (or immune deficiency) is a state in which the immune system's ability to fight infectious disease is compromised or entirely absent.

Global mortality trends reveal convergence clubs and diverging patterns

Study analyzes global mortality trends from 1990 to 2030, identifying five convergence clubs of countries with similar mortality characteristics, revealing patterns of convergence and divergence in mortality and longevity.

18 Jan 2024

Study finds that HIV populations in people with higher viral loads also have higher rates of viral recombination

Researchers investigated whether denser intrahost HIV populations had a higher incidence of coinfection and recombination.

15 Jan 2024

Paxlovid treatment in 20% of COVID-19 patients could avert 850,000 hospitalizations, save up to $170 billion

A study in the Emerging Infectious Diseases journal shows treating 20% of COVID-19 patients with Paxlovid could save up to 0.85 million lives and reduce the economic burden by US $170.17 billion in the US.

14 Jan 2024

Leveraging nutritional interventions for effective TB control

Tuberculosis (TB) is the leading infectious killer worldwide, with 10.6 million cases and 1.6 million deaths in 2021 alone.

13 Jan 2024

Extended liver preservation technique shows promise for daytime transplants

Phase II clinical trial evaluates the safety and feasibility of prolonged DHOPE for extending human donor liver preservation to 20 hours, showing potential for facilitating daytime liver transplantation.

11 Jan 2024

CRISPR cures on the horizon: Breakthrough center aims to heal rare, deadly genetic diseases

Children and adults with rare, deadly genetic diseases have fresh hope for curative therapies, thanks to a new collaboration between the Innovative Genomics Institute (IGI) and Danaher Corporation, a global life sciences and diagnostics innovator.

9 Jan 2024

Fruit fly research solves human disease and fuels new cancer immunotherapy approach

Scientists have solved a cellular murder mystery nearly 25 years after the case went cold. Following a trail of evidence from fruit flies to mice to humans revealed that cannibalistic cells likely cause a rare human immunodeficiency.

5 Jan 2024

Stapled lipopeptides show promise as broad-spectrum antiviral agents

Compounds that obstruct the "landing gear" of a range of harmful viruses can successfully protect against infection by the virus that causes COVID-19, a study published today and led by Dana-Farber Cancer Institute scientists shows.

5 Jan 2024

40-year timeline of HIV: Testing assays, global burden, prevalence, treatment, and challenges

Announcing a new article publication for Zoonoses journal. More than 77 million individuals have been infected with the human immunodeficiency virus (HIV) and approximately 37.6 million people are living with HIV infection.

4 Jan 2024

Factors that increase the risk of severe COVID-19 in children

Study analyzes a nationwide cohort of hospitalized children and adolescents in Germany, identifying key risk factors for severe SARS-CoV-2 infection, including obesity, Trisomy 21, and neurological conditions.

3 Jan 2024

Exploring the global health challenge of hepatitis D

Review explores the global impact of the hepatitis D virus (HDV) on public health, detailing its transmission, clinical course, diagnosis, and treatment options.

2 Jan 2024

UKHSA announces concerning rise in antibiotic-resistant Shigella cases

There has been a concerning rise in cases of extensively antibiotic-resistant Shigella sonnei infections, mainly in gay, bisexual, and other men who have sex with men (GBMSM), UKHSA has announced.

21 Dec 2023

Digital algorithm ePOCT+ successfully reduces antibiotic prescriptions in children, combating antimicrobial resistance

Study demonstrates how the ePOCT+ digital algorithm effectively guides healthcare providers in prescribing antibiotics for children, significantly reducing unnecessary antibiotic use and addressing antimicrobial resistance without compromising patient outcomes.

18 Dec 2023

T-cells step up to offer protection against COVID-19 in B-cell deficient patients

B cell deficiency is a common condition that can result either from immunosuppressant drugs used to treat autoimmune disease or certain cancers -; such as rituximab (RTX) -; or from natural immune deficiency.

18 Dec 2023

Optimizing cervical cancer screening: New study evaluates best approaches for HIV-positive women

Researchers evaluated the effectiveness and outcomes of various cervical cancer screening strategies for women living with HIV in Tanzania, supporting World Health Organisation's (WHO's) 2021 guidelines for reducing cervical cancer mortality in this high-risk group.

14 Dec 2023

Global study reveals link between psychological distress and unhealthy eating in adolescents

Study in Scientific Reports analyzed data from 222,401 adolescents across 61 countries, finding a significant correlation between psychological distress and unhealthy eating habits, with notable differences across sexes and regions.

13 Dec 2023

How does the combined effect of smoking and HIV infection influence the aging-related manifestations?

The combination of human immunodeficiency virus (HIV) infection and smoking influence.

12 Dec 2023

The influence of vitamin supplementation on longitudinal patterns of maternal vitamin status from preconception to post-delivery

Researchers secondary analyzed the NiPPeR randomized clinical trial (RCT) data to assess maternal vitamin levels pre-conception, during pregnancy, and post-delivery and also explored the impact of vitamin supplementation before and during gestation.

11 Dec 2023

The association between viral infections and glioma risk

The causal relationship between viral infection and glioma.

7 Dec 2023

Major UK study finds high demand and efficacy for HIV PrEP among sexual health service attendees

HIV PrEP requirement, duration, uptake, and usage among sexual health services (SHS) attendees in England.

4 Dec 2023