Immunodeficiency News and Research

RSS

Immunodeficiency (or immune deficiency) is a state in which the immune system's ability to fight infectious disease is compromised or entirely absent.

Avanced genome editing technology could be used as a one-time treatment for CD3 delta SCID

A new UCLA-led study suggests that advanced genome editing technology could be used as a one-time treatment for the rare and deadly genetic disease CD3 delta severe combined immunodeficiency.

21 Mar 2023

Study: Patients overwhelmingly prefer to receive test results immediately from online medical portals

Patients overwhelmingly prefer to receive test results as soon as they are available on online medical portals, even if it means viewing the results prior to discussing them with their doctor, a new study co-led by researchers at UT Southwestern and Vanderbilt University medical centers reports.

20 Mar 2023

Benefiting the health of people with diabetes: The WHO Global Diabetes Compact targets

Researchers described the targets of the World Health Organization's (WHOs) Global Diabetes Compact to improve the health outcomes for all individuals affected by this fatal, non-communicable disease.

17 Mar 2023

The role of the fungal mycobiome in women's health

Researchers discuss the association between human mycobiota and female health.

15 Mar 2023

An automated bioinformatics pipeline to monitor HIV data in real-time

Researchers discuss an automated bioinformatics pipeline to prospectively and routinely analyze HIV-1 sequence data

15 Mar 2023

Important backup mechanism of human immune cells elucidated

The enzyme TBK1 is an important component of the innate immune system that plays a critical role in the defense against viruses.

10 Mar 2023

Self-directed autoantibodies against certain chemokines may protect against long-COVID

A recent study published in the journal Nature Immunology discovered autoantibodies against chemokines following severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.

8 Mar 2023

Early safety and efficacy results on a contraceptive vaginal film that inactivates sperm

The current study aimed to explore the contraceptive potential of the human contraceptive antibody-containing vaginal film called ZB-06.

7 Mar 2023

First-in-woman study of a non-hormonal vaginal film showed safety, potential contraceptive efficacy, and supports future development

Researchers developed a novel contraceptive 'ZB-06' a vaginal film containing a human contraceptive antibody called HC4-N that agglutinates sperm.

7 Mar 2023

CDC recommendations and clinical considerations for the treatment of severe Mpox

In a recent article published in the United States (U.S.) Centers for Disease Control and Prevention's (CDC) Morbidity and Mortality Weekly Report, a team of researchers discussed the medical countermeasures and clinical considerations for treating severe manifestations of Mpox.

6 Mar 2023

Antibody levels from prime COVID-19 mRNA vaccine influences the efficacy of booster doses

Researchers evaluate the response of pre-existing immunity to booster doses of mRNA COVID-19 vaccines.

6 Mar 2023

How did people in Zimbabwe respond to drug-resistant tuberculosis alongside COVID-19?

In a recent study posted to the medRxiv* preprint server, researchers described the experiences and coping strategies of people who suffered from drug-resistant tuberculosis (DR-TB) in Zimbabwe between 2020 and 2021.

1 Mar 2023

The evolution of transmissible variants harboring mutations consistent with immune escape in mild community COVID-19 cases

Researchers investigate whether transmissible SARS-CoV-2 variants developed during infection by culturing and sequencing strains obtained from serial oral and nasal samples of community-residing COVID-19 patients.

28 Feb 2023

Exploring the immunomodulatory and anti-inflammatory properties of butyrate

In a recent study published in the journal Fermentation, researchers reviewed studies examining the role of butyrate in inflammatory responses, immunological properties, and diseases related to the immune system such as atopic dermatitis, systemic lupus erythematosus, human immunodeficiency virus (HIV), psoriasis, and cancer.

24 Feb 2023

Exploring Mpox severity among advanced HIV patients

Researchers assessed the incidence of mpox in individuals with advanced human immunodeficiency virus (HIV) infection.

24 Feb 2023

Small molecule inhibitor reverses malignant hyper-editing by an inflammation-induced protein isoform

Researchers at University of California San Diego School of Medicine, Sanford Stem Cell Institute and Moores Cancer Center report that a late-stage, pre-clinical small molecule inhibitor, called rebecsinib, reverses malignant hyper-editing by an inflammation-induced protein isoform, known as ADAR1 p150.

16 Feb 2023

Cohort study examines the incidence of SARS-CoV-2 rebound in patients on oral antivirals

Researchers performed a retrospective population-wide cohort study using anonymized data in Hong Kong, China, between February 26 and July 3, 2022.

16 Feb 2023

Scientists reach a substantial consensus on the four principles that will enable the future development and expansion of virus taxonomy

A team of 45 virologists, evolutionary biologists, bioinformaticians, and structural biologists from around the world arrived at a consensus on virus classification methodologies and presented an integrated taxonomical framework for the systematics and taxonomy of viruses.

15 Feb 2023

Fibromyalgia may occur post-COVID

Researchers investigate the incidence of fibromyalgia among individuals hospitalized due to SARS-CoV-2 infection.

14 Feb 2023

Antibodies against SARS-CoV-2 are higher in infants than in mothers

Researchers characterize the functional and binding antibody responses against SARS-CoV-2 in postpartum women and their infected infants.

9 Feb 2023