Immunohistochemistry News and Research

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Immunohistochemistry (IHC) is an imaging technique to visualize antigens in cells. Labeled antibodies bind to target antigens in the cell to image the distribution and localization of specific proteins of interest

Results from Celgene’s ABRAXANE plus gemcitabine clinical study on resectable pancreatic cancer

Celgene International Sàrl, a subsidiary of Celgene Corporation today announced results from a study of ABRAXANE(paclitaxel protein-bound particles for injectable suspension) (albumin-bound) in combination with gemcitabine in patients with resectable pancreatic cancer.

5 Jun 2012

Study shows valuable role of Mammostrat in assessing ER+ postmenopausal breast cancer patients

GE Healthcare today announced results from the Tamoxifen and Exemestane Adjuvant Multinational (TEAM) Trial at the 2012 Annual Meeting of the American Society of Clinical Oncology.

4 Jun 2012

Data from several clinical trials of ADCETRIS to be presented at ASCO annual meeting

Seattle Genetics, Inc. today announced that data from several clinical trials of ADCETRIS (brentuximab vedotin) will be presented at the 2012 American Society of Clinical Oncology (ASCO) Annual Meeting being held June 1-5, 2012 in Chicago, IL.

4 Jun 2012

Final results from ArQule and Daiichi Sankyo’s tivantinib phase 2 trial on HCC

ArQule, Inc. and Daiichi Sankyo Co., Ltd. today announced final results from a randomized, placebo-controlled, double-blind, phase 2 clinical trial with the selective MET inhibitor tivantinib as a single-agent, investigational, second-line treatment in hepatocellular carcinoma (HCC).

4 Jun 2012

Studies support diagnostic utility of molecular classification in difficult-to-diagnose metastatic cancer

bioTheranostics, Inc., developer of innovative oncology diagnostic tests and solution provider for metastatic cancer, today announced findings from two studies showing high diagnostic accuracy for CancerTYPE ID in determining the primary tumor site in high-grade, metastatic tumors. Results were reported at the 2012 annual meeting of the American Society of Clinical Oncology (ASCO) in Chicago.

2 Jun 2012

Kindstar, Insight Genetics collaborate to improve cancer care in China

Molecular diagnostics company Insight Genetics and Kindstar Globalgene Technology, Inc., China's leading diagnostics company, today announced that the companies are partnering to enhance cancer care in the People's Republic of China and surrounding regions.

1 Jun 2012

Ventana, leading cancer researchers partner to commercialize novel IHC primary antibody

Ventana Medical Systems, Inc., a member of the Roche Group, has signed an exclusive license agreement with the German Cancer Research Center and University Hospital Heidelberg, Germany to commercialize a novel immunohistochemistry (IHC) primary antibody developed by researchers Andreas von Deimling, MD, Hanswalter Zentgraf, PhD and David Capper, MD, to detect the V600E BRAF mutation protein.

1 Jun 2012

New light on many biological differences between individual breast cancers

New findings presented at Europe's leading breast cancer translational research conference this year shed new light on the many biological differences between individual breast cancers.

4 May 2012

NeoGenomics first quarter revenue increases 72% to $15.2 million

NeoGenomics, Inc., a leading provider of cancer-focused genetic testing services today reported its results for the first quarter 2012.

25 Apr 2012

Bimodal genes can define molecular subtypes of ovarian cancer

Scientists from Duke University Medical Center have determined that genes acting as molecular "on/off" switches can define clinically relevant molecular subtypes of ovarian cancer, providing ideal potential targets for use in clinical prognostic and diagnostic testing.

9 Apr 2012

DBS introduces novel Multiplex Immunohistochemistry cancer kits

Diagnostic Biosystems, a specialty Immunohistochemistry company, announces its debut as an automated IHC company, introducing the Mosaic 360 System with a product offering of novel Multiplex Immunohistochemistry kits and a complementary line of optimized IHC reagents.

19 Mar 2012

Amylin may lead to severe heart damage in obese and diabetic patients

Severe heart damage in people who are obese and diabetic is linked with a pancreatic hormone called amylin, UC Davis researchers have found.

17 Feb 2012

IBM's non-contact, microfluidic, silicon probe minimizes patient discomfort

IBM scientists have developed a flexible, non-contact microfluidic probe made from silicon that can aid researchers and pathologists to investigate critical tissue samples accurately for drug discovery and disease diagnostics.

13 Jan 2012

HDC, NeoGenomics sign worldwide licensing agreement to develop LDT

Health Discovery Corporation, a molecular diagnostics leader in the use of patent protected advanced mathematical techniques for personalized medicine, has entered into an exclusive worldwide licensing agreement with NeoGenomics, Inc. for laboratory developed tests in the Field of hematopoietic and solid tumor cancers excluding breast cancer, which was previously licensed to Quest Diagnostics and Smart Personalized Medicine and excluding cancer of the retina which was previously committed to Retinalyze, LLC.

9 Jan 2012

Amyloid precursor protein fragment may be a biomarker for autism

Immune system abnormalities that mimic those seen with autism spectrum disorders have been linked to the amyloid precursor protein (APP), reports a research team from the University of South Florida's Department of Psychiatry and the Silver Child Development Center.

4 Jan 2012

Celerus Diagnostics receives three U.S. patents that cover key cancer technologies

Celerus Diagnostics, developer of the Wave RPD System and global leader in rapid immunohistochemistry for cancer diagnosis, announced today that the Company has been issued three important patents by the United States Patent and Trademark Office.

19 Nov 2011

Critical migrating neurons in the human brain decline during infancy

José Manuel García Verdugo, full professor of Cell Biology at University of Valencia, together with a University of California research team, has participated in the discovery of new pathways of neurons migrating from lateral ventricles to the prefrontal cortex. The work done in chidren at early ages reveals a new cell pathway which may increase the amount of neurons in regions important for cognitive tasks, emotional processes and spatial perception.

22 Oct 2011

NeoGenomics third quarter revenue increases 30% to $11.3 million

NeoGenomics, Inc., a leading provider of cancer-focused genetic testing services today reported its results for the third quarter 2011.

19 Oct 2011

USPTO awards HistoRx two patents for methods of standardization of digital microscopy instruments

HistoRx, the leader in quantitative immunohistochemistry, advances its proprietary position in digital pathology through the recent issuance of US patents covering key features necessary for achievement of reproducible, standardized image analysis results.

7 Oct 2011

Combination of P16 immunohistochemistry, DNA qPCR can accurately detect oropharyngeal cancer

Researchers have determined that a combination of P16 immunohistochemistry and DNA qPCR to test for viral E6 can accurately determine the oropharyngeal squamous cell carcinoma, a form of head and neck cancer, which derive from HPV16, according to a study published in Clinical Cancer Research, a journal of the American Association for Cancer Research.

3 Oct 2011

Immunohistochemistry News and Research

Further Reading

Results from Celgene’s ABRAXANE plus gemcitabine clinical study on resectable pancreatic cancer

Study shows valuable role of Mammostrat in assessing ER+ postmenopausal breast cancer patients

Data from several clinical trials of ADCETRIS to be presented at ASCO annual meeting

Final results from ArQule and Daiichi Sankyo’s tivantinib phase 2 trial on HCC

Studies support diagnostic utility of molecular classification in difficult-to-diagnose metastatic cancer

Kindstar, Insight Genetics collaborate to improve cancer care in China

Ventana, leading cancer researchers partner to commercialize novel IHC primary antibody

New light on many biological differences between individual breast cancers

NeoGenomics first quarter revenue increases 72% to $15.2 million

Bimodal genes can define molecular subtypes of ovarian cancer

DBS introduces novel Multiplex Immunohistochemistry cancer kits

Amylin may lead to severe heart damage in obese and diabetic patients

IBM's non-contact, microfluidic, silicon probe minimizes patient discomfort

HDC, NeoGenomics sign worldwide licensing agreement to develop LDT

Amyloid precursor protein fragment may be a biomarker for autism

Celerus Diagnostics receives three U.S. patents that cover key cancer technologies

Critical migrating neurons in the human brain decline during infancy

NeoGenomics third quarter revenue increases 30% to $11.3 million

USPTO awards HistoRx two patents for methods of standardization of digital microscopy instruments

Combination of P16 immunohistochemistry, DNA qPCR can accurately detect oropharyngeal cancer

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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