Inflammasome News and Research

RSS

Emergency C-section may compromise development and long-term health of babies

Labor and natural childbirth causes stress on a mother’s body but an emergency Caesarean is associated with even more inflammatory gene expression in the placenta, new South Australian research shows.

6 Apr 2022

Higher cereal fiber intake associated with lower inflammation

A new study assesses the association between dietary fiber intake with inflammatory markers associated with cardiovascular disease.

4 Apr 2022

The different actions of CBD in SARS-CoV-2 infection

An article has described the role of cannabidiol as a potential inhibitor of hyperinflammation in SARS-CoV-2 infection.

29 Mar 2022

Narrative review reports two important mediators in SARS-CoV-2-induced ischemic stroke recovery

Researchers explored neuroinflammation and COVID-19-induced ischemic stroke recovery.

17 Mar 2022

‘Foreign body reaction’ to implants can be reduced by incorporating drug into silicone coating

Long-term use of implantable electronic medical devices – such as pacemakers and cochlear implants – is hampered by the body's reaction to foreign bodies.

14 Mar 2022

Exercise counters inflammation that leads to diabetes, depression after COVID-19

While no medically recognized treatment exists for Long COVID, exercise may break the vicious cycle of inflammation that can lead to developing diabetes and depression months after a person recovers from the virus.

11 Mar 2022

Elevated P2X7 receptor levels in COVID-19 patients correlate with disease severity

In a recent study posted to the bioRxiv preprint server, researchers demonstrated that the soluble P2X7 receptor is increased in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) patients. They also showed that the elevated P2X7 receptors correlated with coronavirus disease 2019 (COVID-19) severity.

9 Mar 2022

Melatonin as a safe and potentially life-saving treatment for COVID-19

A new study discusses the possible role of melatonin, an antioxidant and anti-inflammatory agent, in treating COVID-19.

24 Feb 2022

SARS-CoV-2 viroporins mediate cytokine storm via mitochondrial permeability transition pore

Researchers demonstrated that the SARS-CoV-2 viroporins precipitate cytokine storm via the alteration of mitochondrial physiology in severe COVID-19.

24 Feb 2022

Study suggests tea polyphenols may modulate COVID-19 via intestinal microbiota

A new study discusses the state of current knowledge about the potential use of tea polyphenols in the prevention and treatment of COVID-19.

16 Feb 2022

Yale researchers confirm the health benefits of moderate calorie restrictions in humans

Decades of research has shown that limits on calorie intake by flies, worms, and mice can enhance life span in laboratory conditions. But whether such calorie restriction can do the same for humans remains unclear.

11 Feb 2022

Study explores inflammation of endothelial cells by exosomes from COVID-19 patients

In a new study, researchers revealed that the nucleotide-binding oligomerization domain-like receptors or NOD-like receptors family pyrin domain containing 3 (NLRP3) inflammasome is activated by the exosomes from plasma in COVID-19.

9 Feb 2022

Colchicine holds promise to reduce the risk of severe COVID-19

A recent article, published in Rheumatology and Therapy, reviews the potent evidence of colchicine against the SARS-CoV-2 infection.

7 Feb 2022

Investigating the immunology of COVID-19 infected children

Researchers published a new study that focused on the key principles of developmental immunology associated with immunobiology and the clinical impacts of COVID-19 infections in children and adults.

7 Feb 2022

Innate immune processes involved in SARS-CoV-2 recognition and resultant inflammation

A new article reviewed the innate immune detection and signaling pathways that the host uses against SARS-CoV-2.

7 Feb 2022

Representative structures of SARS-CoV-2 and development of therapeutic agents for targeting these proteins

Researchers from China summarized the representative structures of SARS-CoV-2 proteins and discussed the development of novel therapeutic agents for targeting these proteins to treat and prevent COVID-19.

2 Feb 2022

Study shows SARS-CoV-2 prompts NLRP3 inflammasome activation through spike-ACE2 receptor interaction

New research assesses the NLR family pyrin domain containing 3 (NLRP3) inflammasome activation in response to SARS-CoV-2 and its spike protein, and the effects of this exposure in the presence of a-synuclein protein aggregate fibrils.

17 Jan 2022

First-responder cells launching the repair after heart attack promote inflammation overdrive

First-responder cells launching the repair after a heart attack are so frantic about fixing the damage that they promote more inflammation than necessary, new research in mice suggests.

5 Jan 2022

Impact of tumor environments on susceptibility and course of disease in those infected with SARS-CoV-2

A review assessed the impact of "hot" vs. "cold" immune/tumor environments (and associated therapies) on susceptibility and disease course in subjects with these two types of tumors and infected with SARS-CoV-2 to decipher the mechanisms that drive these adverse outcomes in COVID-19 infected cancer patients.

13 Dec 2021

UVA researchers uncover common link between lupus and macular degeneration

University of Virginia School of Medicine researchers have made a discovery linking lupus, a potentially debilitating autoimmune disorder, and macular degeneration, a leading cause of blindness.

9 Dec 2021

Inflammasome News and Research

Emergency C-section may compromise development and long-term health of babies

Higher cereal fiber intake associated with lower inflammation

The different actions of CBD in SARS-CoV-2 infection

Narrative review reports two important mediators in SARS-CoV-2-induced ischemic stroke recovery

‘Foreign body reaction’ to implants can be reduced by incorporating drug into silicone coating

Exercise counters inflammation that leads to diabetes, depression after COVID-19

Elevated P2X7 receptor levels in COVID-19 patients correlate with disease severity

Melatonin as a safe and potentially life-saving treatment for COVID-19

SARS-CoV-2 viroporins mediate cytokine storm via mitochondrial permeability transition pore

Study suggests tea polyphenols may modulate COVID-19 via intestinal microbiota

Yale researchers confirm the health benefits of moderate calorie restrictions in humans

Study explores inflammation of endothelial cells by exosomes from COVID-19 patients

Colchicine holds promise to reduce the risk of severe COVID-19

Investigating the immunology of COVID-19 infected children

Innate immune processes involved in SARS-CoV-2 recognition and resultant inflammation

Representative structures of SARS-CoV-2 and development of therapeutic agents for targeting these proteins

Study shows SARS-CoV-2 prompts NLRP3 inflammasome activation through spike-ACE2 receptor interaction

First-responder cells launching the repair after heart attack promote inflammation overdrive

Impact of tumor environments on susceptibility and course of disease in those infected with SARS-CoV-2

UVA researchers uncover common link between lupus and macular degeneration

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

Latest Life Science News