Inflammatory Disease News and Research

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New tool for analyzing genetic variations in the inflammation pathways

Scientists have known which genes are linked to inflammation, but now researchers at Wake Forest University Baptist Medical Center have organized this information to develop a powerful tool to aid investigators in studying the genetics of inflammatory diseases.

3 Dec 2007

Discovery of new signaling molecule could lead to the development of new treatments for cancer

Investigators at St. Jude Children's Research Hospital have discovered a new signaling molecule that prevents immune responses from running amok and damaging the body.

21 Nov 2007

Blood clotting protein fibrin plays a role in rheumatoid arthritis

Researchers at Cincinnati Children's have issued the first study showing that a protein normally involved in blood clotting (fibrin), also plays an important role in the inflammatory response and development of rheumatoid arthritis.

19 Nov 2007

Hidden epidemic of sexually transmitted diseases in the U.S.

Health experts in the United States say the country has achieved an all-time record for a sexually transmitted disease.

14 Nov 2007

Discovery of key pathway, potential drug targets in autoinflammatory disease

Molecular biologists at Jefferson's Kimmel Cancer Center in Philadelphia have detailed the cascade of cellular events behind some potentially dangerous autoinflammatory diseases.

13 Nov 2007

Researchers identify gene behind rheumatoid arthritis

University of Manchester researchers have identified a genetic variant in a region on chromosome 6 that is associated with rheumatoid arthritis (RA), the most common inflammatory arthritis affecting 387,000 people in the UK.

From The University of Manchester 5 Nov 2007

Herb rosemary fights free radical damage in the brain

Rosemary not only tastes good in culinary dishes such as Rosemary chicken and lamb, but scientists have now found it is also good for your brain.

31 Oct 2007

Most people living longer except rheumatoid arthritis sufferers

New research by the Mayo Clinic has found that while most people are living longer the same is not true for sufferers from rheumatoid arthritis.

30 Oct 2007

Comparison of mortality trends among rheumatoid arthritis subjects

An autoimmune inflammatory disease that takes a progressive toll on the heart, kidney and liver as well as the joints, rheumatoid arthritis (RA) is associated with a high risk of early death.

29 Oct 2007

Gold-like drugs to treat arthritis

Scientists at Duke University Medical Center may have solved the mystery surrounding the healing properties of gold - a discovery they say may renew interest in gold salts as a treatment for rheumatoid arthritis and other inflammatory diseases.

22 Oct 2007

Genes that increase rheumatoid arthritis risk found

Researchers in the United States and Sweden have identified a genetic region associated with increased risk of rheumatoid arthritis (RA), a chronic and debilitating inflammatory disease of the joints that affects an estimated 2.1 million Americans.

8 Oct 2007

Specific immune deficiency pinpointed as likely cause of ulcerative colitis

In a series of mouse experiments, researchers at the Harvard School of Public Health (HSPH) have pinpointed a specific immune deficiency as the likely fundamental cause of ulcerative colitis, a chronic, sometimes severe inflammatory disease of the colon or large intestine that afflicts half a million Americans.

4 Oct 2007

Promising trial results show biologic therapy ustekinumab significantly improved psoriasis

The first reported findings from an international, Phase 3 study showed that more than two-thirds of patients with moderate to severe plaque psoriasis receiving two doses of ustekinumab (CNTO 1275) achieved at least a 75 percent reduction in psoriasis at week 12, the primary endpoint of the study, as measured by the Psoriasis Area and Severity Index (PASI 75).

4 Oct 2007

Hydrogen sulfide based drug shows promise in reducing heart-attack damage

Producing a state of "hibernation on demand" in mice by administering an experimental drug from Ikaria (an injectable formulation of the biological gas hydrogen sulfide) showed promise in a study designed to reduce damage from heart attacks.

26 Sep 2007

Childhood vaccination for the rubella virus may protect adult eyes

Childhood vaccination for the rubella virus may have also almost entirely eliminated an inflammatory eye disease from the U.S.-born population, according to a study by researchers at the University of Illinois at Chicago.

20 Sep 2007

Benefits and risks of breastfeeding

Extensive medical research shows that mothers' milk satisfies babies' nutritional needs far better than any manufactured infant formula.

17 Sep 2007

LL37 peptide provides a new potential target for autoimmune disease

A human peptide that acts as a natural antibiotic against invading microbes can also bind to the body's own DNA and trigger an immune response in the absence of an infection, a research team led by scientists at The University of Texas M. D. Anderson Cancer Center reports in an early online publication in Nature.

17 Sep 2007