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New gene therapy can nearly eliminate arthritis pain

Early-stage research has found that a new gene therapy can nearly eliminate arthritis pain, and significantly reduce long-term damage to the affected joints, according to a study published today in the journal Arthritis and Rheumatism.

28 May 2007

Complement receptor 3 sends a signal to dampen the immune system

Researchers from The Children's Hospital of Philadelphia and The University of Pennsylvania reported that complement receptor 3 (CR3), a protein found on cell surfaces, inhibits dendritic cells, the sentinels of the immune system, from setting off an alarm signal that brings on a full immune response.

16 May 2007

First comprehensive profile of cell movement

Researchers at the University of California, San Diego (UCSD) School of Medicine have developed new technology which, combined with proteomics, the large-scale study of the structure and function of proteins and their functions, has allowed them to map an extensive network of the signaling proteins that control cell movement.

8 May 2007

Infliximab fails to improve chronic obstructive pulmonary disease symptoms

A promising anti-inflammatory drug failed to improve symptoms of moderate to severe chronic obstructive pulmonary disease, or COPD, in a large, multi-center trial.

2 May 2007

Ratio of women stricken with MS rockets by 50% each decade

According to a study in the United States although women have always had a greater susceptibility for developing Multiple Sclerosis (MS) than men, the numbers have rocketed in the last six decades.

29 Apr 2007

Burnham awarded $7.39 million for study on Neuron-Glia communication in development

A team of researchers at the Burnham Institute for Medical Research (“Burnham”) has been awarded $7.39 million from the National Institute of Child Health and Human Development of the National Institutes of Health.

24 Apr 2007

Bacteria barge inside guard cells and initiate a powerful immune response

Immune cells that are the body's front-line defense don't necessarily rest quietly until invading bacteria lock onto receptors on their outside skins and rouse them to action, as previously thought.

18 Apr 2007

MS patients not receiving medications to slow disease progression

Neurologists at Wake Forest University Baptist Medical Center have found that many patients diagnosed with multiple sclerosis (MS) are not taking or being prescribed drugs approved to treat the disease.

17 Apr 2007

Bacteria can barge inside immune cells

Immune cells that are the body's front-line defense don't necessarily rest quietly until invading bacteria lock onto receptors on their outside skins and rouse them to action, as previously thought. In a new paper, University of Michigan scientists describe their findings that bacteria can barge inside these guard cells and independently initiate a powerful immune response.

14 Apr 2007

Researchers show blood-brain barrier damage could affect multiple sclerosis severity

Immunology researchers at the Kimmel Cancer Center at Jefferson studying a multiple sclerosis (MS)-like disease in mice have shown that the amount of "damage" to the central nervous system's protective blood-brain barrier, in essence, opening it, almost always correlates to the severity of the disease.

7 Apr 2007

Efficacy of Guanilib confirmed for inflammatory bowel disease

Callisto Pharmaceuticals has announced additional data confirming efficacy of Guanilib, a first-in-class compound currently being developed for the treatment of inflammatory bowel disease (IBD), in two different standard animal models of experimental colitis.

7 Apr 2007

Connection found between allergic diseases and autoimmune diseases

A new study by researchers at Children's Hospital and Regional Medical Center and the University of Washington (UW) identifies a connection between allergic diseases such as atopic dermatitis, also known as eczema, and autoimmune diseases. The study was published in the April 1, 2007 edition of Nature Immunology.

4 Apr 2007

We need to balance out our intake of omega-6 and omega-3 fatty acids

A new study suggests that people whose diets contain dramatically more of one kind of polyunsaturated fatty acid than another may be at greater risk for both clinical depression and certain inflammatory diseases.

3 Apr 2007

Brain's immune system plays protective role in early Alzheimer's disease

The immune system's response against amyloid-beta, the protein that forms plaques in the brains of patients with Alzheimer's disease, appears to protect the brain from damage in early stages of the devastating neurological disorder.

30 Mar 2007

It's a fact stress makes teens spotty!

The study looked at whether levels of sebum, the oily substance that coats the skin and protects the hair, increase in times of stress and are related to acne severity.

8 Mar 2007

Stress increases acne in teens

The largest study ever conducted on acne and stress reveals that teenagers who were under high levels of stress were 23 percent more likely to have increased acne severity, according to researchers from Wake Forest University School of Medicine and colleagues.

5 Mar 2007

Treatment for gum disease could also help the heart

Scientists at University College London (UCL) have conducted the first clinical trial to demonstrate that an intensive treatment for periodontitis (gum disease) directly improves the health of blood vessels.

4 Mar 2007

FDA approves Humira (adalimumab) for Crohn's disease

The U.S. Food and Drug Administration (FDA) today approved Humira (adalimumab) to treat adult patients with moderately to severely active Crohn's disease, a chronic inflammatory disease of the intestines, which affects an estimated one million Americans.

27 Feb 2007

Search for vaccine to prevent Chlamydia

It's the most common bacteria-related sexually transmitted disease in the United States, so researchers at The University of Texas at San Antonio's South Texas Center for Emerging Infectious Diseases (STCEID) and The University of Texas at San Antonio Health Science Center have partnered to discover a vaccine that will prevent Chlamydia.

19 Feb 2007

Dll4 signalling through Notchi regulates formation of tip cells during angiogenesis

All tissues, sick and healthy alike, need a blood supply to survive and grow. The key to many medical problems, like preventing tumour development, is therefore to obstruct the spread of the blood vessels. Research scientists at Karolinska Institutet have now discovered a heretofore unknown mechanism for how the body links together its blood vessels.

29 Jan 2007