Insulin News and Research

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Insulin is a hormone that is needed to convert glucose, starches and other food into energy needed for daily life. Insulin allows cells to use glucose for fuel and is secreted by beta cells in the islets of Langerhans. The release of insulin from the pancreas is stimulated by increased blood glucose, vagal nerve stimulation, and other factors. Insulin is obtained from various animals and available in a variety of preparations. Commercial insulin preparations differ in a number of ways, including differences in the animal species from which they are obtained; their purity, concentration, and solubility; and the time of onset and duration of their biologic action. An oral hypoglycemic agent is not a form of insulin therapy.

Unilife Corporation 2010 fourth quarter revenue increases to $2.7 million

Unilife Corporation today announced preliminary financial results for the fourth quarter and fiscal year ended June 30, 2010.

31 Aug 2010

BioMarin's BMN-701 receives FDA orphan drug designation for treatment of Pompe disease

BioMarin Pharmaceutical Inc. announced today that it has received orphan drug designation from the U.S. Food and Drug Administration (FDA) for BMN-701, a novel fusion of insulin-like growth factor 2 and alpha glucosidase (IGF2-GAA) in development for the treatment of Pompe disease. An investigational new drug application (IND) for BMN-701 has been submitted, investigational material has been manufactured and a Phase I/II study is expected to start in the first quarter of 2011.

30 Aug 2010

David Mosser to discuss primary duty of macrophages at American Physiological Society conference

The term "macrophage" conjures images of a hungry white blood cell gobbling invading bacteria. However, macrophages do much more than that. Not only do they act as antimicrobial warriors, they also play critical roles in immune regulation and wound-healing. They can respond to a variety of cellular signals and change their physiology in response to local cues.

27 Aug 2010

Type 2 diabetes, insulin resistance increases risk for Alzheimer's disease: Research

People with insulin resistance and type 2 diabetes appear to be at an increased risk of developing plaques in the brain that are associated with Alzheimer's disease, according to new research published in the August 25, 2010, issue of Neurology, the medical journal of the American Academy of Neurology.

26 Aug 2010

Naringenin from grape fruits initiates increased fatty acid oxidation, inhibits vLDL production

Naringenin, an antioxidant derived from the bitter flavor of grapefruits and other citrus fruits, may cause the liver to break down fat while increasing insulin sensitivity, a process that naturally occurs during long periods of fasting.

26 Aug 2010

Stem cell therapy cures 12-year-old boy with diabetes

Cellonis Biotechnologies, a Beijing and HK-based medical research and application company, has recorded some remarkable results in the treatment of a twelve-year-old boy with diabetes using their stem cell therapy in a Beijing partner hospital. He has completely regained his normal life, enjoying sports and school activities just like every other person his age, and has been free from injections and drugs for more than half a year.

25 Aug 2010

MRI and MR spectroscopy determine internal fat distribution: Study

Why is it that some people lose weight and body fat when they exercise and eat less and others don't. German researchers say MRI and magnetic resonance (MR) spectroscopy can provide the answer and help predict who will benefit from lifestyle changes.

25 Aug 2010

Two diabetes medications increase risk of heart attack, failure: Study

In contrast to previous reports, the risks of the composite endpoint of heart attack, heart failure, both, or death were the same about 4 percent for patients taking the diabetes drugs rosiglitazone or pioglitazone, according to a study published in the American Heart Association journal Circulation: Cardiovascular Quality and Outcomes.

25 Aug 2010

Water soluble extract of cinnamon reduces diabetes and heart disease risk

A study led by U.S. Department of Agriculture (USDA) chemist Richard Anderson suggests that a water soluble extract of cinnamon, which contains antioxidative compounds, could help reduce risk factors associated with diabetes and heart disease.

25 Aug 2010

Access Pharmaceuticals to highlight Cobalamin nanotechnology at ACS National Meeting

ACCESS PHARMACEUTICALS, INC.,a biopharmaceutical company specializing in products for cancer and supportive care, announced that its Director of Chemistry and Quality, Dr. Ric Zarzycki will give an invited presentation today on the Company's Cobalamin nanoparticle technology at a thought-leadership symposium being held at the American Chemical Society's ("ACS") 240th National Meeting & Exposition, at Boston Convention and Exhibition Center in Boston, Massachusetts, August 22-26, 2010.

25 Aug 2010

Medtronic 2011 first quarter revenue decreases 4%

Medtronic, Inc. today announced financial results for its first quarter of fiscal year 2011, which ended July 30, 2010.

24 Aug 2010

Special empowerment program to promote confidence in diabetic children

Teens are learning how to shred down the mountain and balance blood sugars in a special empowerment program called Riding on Insulin, taking place December 11, 2010, at The Canyons Resort in Park City. The day, led by Sean Busby,26 year old professional snowboarder with type 1 diabetes promotes courage and confidence and shows children with type 1 or type 2 they can overcome mental and physical challenges.

24 Aug 2010

Scientists develop new synthetic material to grow stem cells

Human pluripotent stem cells, which can become any other kind of body cell, hold great potential to treat a wide range of ailments, including Parkinson's disease, multiple sclerosis and spinal cord injuries. However, scientists who work with such cells have had trouble growing large enough quantities to perform experiments - in particular, to be used in human studies. Furthermore, most materials now used to grow human stem cells include cells or proteins that come from mice embryos, which help stimulate stem-cell growth but would likely cause an immune reaction if injected into a human patient.

23 Aug 2010

Study supports role for SNARK protein in regulating glucose transport during muscle contraction and exercise

Skeletal muscles combust both lipids and carbohydrates during exercise. The carbohydrates consist of both glycogen stored in the muscles as well as glucose extracted from the blood. Being a major sink for glucose disposal, skeletal muscle represents an important model tissue for studying the intracellular signaling pathways leading to increased glucose transport.

21 Aug 2010

Dilation of blood vessels restores muscle synthesis in elderly

University of Texas Medical Branch at Galveston researchers believe they've found a way to use widely available blood pressure drugs to fight the muscular weakness that normally accompanies aging.

21 Aug 2010

New ways to tackle diabetes

According to a new analysis from UK, a diet rich in green leafy vegetables may reduce the risk of developing diabetes. The inference was drawn from six studies which looked into fruit and vegetable intake and found that only food including spinach and cabbage was found to have a significant positive effect. The findings were published in the British Medical Journal (BMJ).

19 Aug 2010

Scientist suggests emodin can reduce impact of type 2 diabetes

Emodin, a natural product that can be extracted from various Chinese herbs including Rheum palmatum and Polygonum cuspidatum, shows promise as an agent that could reduce the impact of type 2 diabetes. Findings published in this month's edition of the British Journal of Pharmacology show that giving emodin to mice with diet-induced obesity lowered blood glucose and serum insulin, improved insulin resistance and lead to more healthy levels of lipid in the blood. It also decreased body weight and reduced central fat mass.

18 Aug 2010

BioMarin Pharmaceutical acquires ZyStor Therapeutics, furthers development of ZC-701 for Pompe disease

BioMarin Pharmaceutical Inc. announced today that it has acquired ZyStor Therapeutics, Inc. (ZyStor), a privately-held biotechnology company developing enzyme replacement therapies (ERT) for the treatment of lysosomal storage disorders. ZyStor's lead product candidate is ZC-701, a novel fusion of insulin-like growth factor 2 and alpha glucosidase (IGF2-GAA) in development for Pompe disease.

18 Aug 2010

Bariatric surgery can result in sustained reversal of obesity, type 2 diabetes: Study

Results of a large national study show that nearly three-quarters of obese patients with type 2 diabetes who undergo weight-loss surgery are able to stop insulin and other antidiabetes drugs within six months. In the Johns Hopkins study of insured, obese, diabetic patients, researchers also found that in the third year following surgery, average annual health care costs per patient decreased by more than 70 percent. The study is published in the Archives of Surgery this month.

17 Aug 2010

JDRF announces key step on road to artificial pancreas

JDRF announced today another important step on the road to the development of an artificial pancreas - an automated system to better manage the blood sugar of people with type 1 diabetes - with the establishment of a research program to speed the development of faster-acting insulin.

17 Aug 2010

Insulin News and Research

Further Reading

Unilife Corporation 2010 fourth quarter revenue increases to $2.7 million

BioMarin's BMN-701 receives FDA orphan drug designation for treatment of Pompe disease

David Mosser to discuss primary duty of macrophages at American Physiological Society conference

Type 2 diabetes, insulin resistance increases risk for Alzheimer's disease: Research

Naringenin from grape fruits initiates increased fatty acid oxidation, inhibits vLDL production

Stem cell therapy cures 12-year-old boy with diabetes

MRI and MR spectroscopy determine internal fat distribution: Study

Two diabetes medications increase risk of heart attack, failure: Study

Water soluble extract of cinnamon reduces diabetes and heart disease risk

Access Pharmaceuticals to highlight Cobalamin nanotechnology at ACS National Meeting

Medtronic 2011 first quarter revenue decreases 4%

Special empowerment program to promote confidence in diabetic children

Scientists develop new synthetic material to grow stem cells

Study supports role for SNARK protein in regulating glucose transport during muscle contraction and exercise

Dilation of blood vessels restores muscle synthesis in elderly

New ways to tackle diabetes

Scientist suggests emodin can reduce impact of type 2 diabetes

BioMarin Pharmaceutical acquires ZyStor Therapeutics, furthers development of ZC-701 for Pompe disease

Bariatric surgery can result in sustained reversal of obesity, type 2 diabetes: Study

JDRF announces key step on road to artificial pancreas

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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