Interleukin News and Research

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Immunosuppressive therapies for COVID-19 treatment

In a new study, researchers assessed the impact of baricitinib, netakimab, and tocilizumab against coronavirus disease 2019 (COVID-19).

31 Aug 2022

FAU and Tel Aviv researchers receive grant to tackle Alzheimer’s-related mood disorders

Alzheimer's disease (AD) is the most common type of dementia affecting an estimated 6.3 million Americans age 65 and older. Without the development of medical breakthroughs to prevent, treat, slow or cure AD that number could grow to 13.8 million by 2060.

29 Aug 2022

Is there an association between the gut microbiome of people within different countries and the severity of COVID-19?

Researchers explored the complex relationship between the gut microbiome of people in different countries and the observed COVID-19 severity, measured as the hospitalization rate of the corresponding country.

29 Aug 2022

High-throughput proteomics reveals pregnancy-specific responses to COVID-19

Researchers evaluated pregnancy-specific responses to SARS-CoV-2 infection.

29 Aug 2022

How does the maternal immune response balance SARS-CoV-2 antiviral responses with transplacental transfer of protection to the fetus?

Researchers found that in SARS-CoV-2 maternal infection, the balance between antiviral response and transplacental transfer of humoral and cellular protection relies on maternal IL-6 and IL10.

29 Aug 2022

What is the association between T lymphocyte-mediated immune responses and COVID-19 severity?

Researchers examined the relationship between cell-mediated or T lymphocyte-mediated immunity and SARS-CoV-2 infection severity.

25 Aug 2022

Optimized human small intestinal organoids can help better study the functioning of small intestines

Researchers from the Organoid group (formerly the Clevers group) have improved human small intestinal organoids – miniature versions of the small intestine.

24 Aug 2022

Glucokinase activator AZD1656 shows potential benefit for diabetics with moderate to severe COVID-19

A new study examines the potential benefit of the glucokinase activator molecule AZD1656 in the ARCADIA trial.

23 Aug 2022

“Drug factory” implants show promise in eradicating mesothelioma tumors

Rice University and Baylor College of Medicine researchers have shown they can eradicate advanced-stage mesothelioma tumors in mice in just a few days with a treatment combining Rice's cytokine "drug factory" implants and a checkpoint inhibitor drug.

22 Aug 2022

Scientists identify new driver for rare type of liver cancer

Scientists from the German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ) and the Hebrew University in Jerusalem have identified in mice the cell of origin of combined liver/biliary duct carcinomas, a rare type of cancer of the liver.

19 Aug 2022

CD98 identified as a key mediator of pro-fibrotic and acute inflammatory responses in the lung

Researchers investigated the role of the CD98 glycoprotein in inducing an inflammatory response to SARS-CoV-2 in patients of progressive fibrosis interstitial lung diseases, including the archetypal PFILD, idiopathic pulmonary fibrosis.

18 Aug 2022

What are the unique traits of Long COVID?

In a new study, researchers identified distinctive characteristics of post-acute sequelae of COVID-19 (PASC) via immune profiling.

12 Aug 2022

Review of natural products with promising anti-SARS-CoV-2 potential

In a new study, researchers reviewed existing literature on naturally active products with therapeutic efficacy against SARS-CoV-2.

10 Aug 2022

B-cell responses to COVID mRNA vaccine are enhanced by a 16-week interval between doses

Researchers assess the impact of extending the interval between primary and booster COVID-19 vaccine doses.

9 Aug 2022

Study suggests BA.5 evolved to induce enhanced inflammation when compared to prior Omicron subvariants

Researchers evaluated the comparative pathogenicity of SARS-CoV-2 Omicron sub-variants BA.1, BA.2, and BA.5, in vitro and in vivo.

9 Aug 2022

Alzheimer’s disease is associated with characteristic gut metabolomic signatures

Scientists review current literature associated with the role of the gut-brain axis in AD pathogenesis.

9 Aug 2022

The safety and preliminary efficacy of OP-101 in patients with severe COVID-19

Researchers assessed the impact of dendrimer nanotherapy in treating severe COVID-19.

8 Aug 2022

Exposure to air pollutants released during wildfires has ill effects among children

New research linking air pollution data from federal monitors in the Sacramento area of California, including during significant fires, is showing ill effects of pollution exposure among children, a new University of California, Davis, study suggests.

4 Aug 2022

Disease progression in the rhesus macaque model upon inoculation with the Delta, Omicron BA.1, and Omicron BA.2 variants

Researchers compared the severity levels of disease caused by different SARS-CoV-2 variants of concern in the rhesus macaque model.

4 Aug 2022

A combined influenza and COVID-19 mRNA vaccine

A combined mRNA vaccine is capable of inducing broad and durable protection against co-infection with SARS-CoV-2 and IAV,

3 Aug 2022

Interleukin News and Research

Immunosuppressive therapies for COVID-19 treatment

FAU and Tel Aviv researchers receive grant to tackle Alzheimer’s-related mood disorders

Is there an association between the gut microbiome of people within different countries and the severity of COVID-19?

High-throughput proteomics reveals pregnancy-specific responses to COVID-19

How does the maternal immune response balance SARS-CoV-2 antiviral responses with transplacental transfer of protection to the fetus?

What is the association between T lymphocyte-mediated immune responses and COVID-19 severity?

Optimized human small intestinal organoids can help better study the functioning of small intestines

Glucokinase activator AZD1656 shows potential benefit for diabetics with moderate to severe COVID-19

“Drug factory” implants show promise in eradicating mesothelioma tumors

Scientists identify new driver for rare type of liver cancer

CD98 identified as a key mediator of pro-fibrotic and acute inflammatory responses in the lung

What are the unique traits of Long COVID?

Review of natural products with promising anti-SARS-CoV-2 potential

B-cell responses to COVID mRNA vaccine are enhanced by a 16-week interval between doses

Study suggests BA.5 evolved to induce enhanced inflammation when compared to prior Omicron subvariants

Alzheimer’s disease is associated with characteristic gut metabolomic signatures

The safety and preliminary efficacy of OP-101 in patients with severe COVID-19

Exposure to air pollutants released during wildfires has ill effects among children

Disease progression in the rhesus macaque model upon inoculation with the Delta, Omicron BA.1, and Omicron BA.2 variants

A combined influenza and COVID-19 mRNA vaccine

Exploring the intersection of biology and proteomics

Unlocking the Secrets of Multiple Sclerosis Progression: Brain-Immune Cell Communication

Passing on Polycystic Ovary Syndrome: Health risks for male offspring of women with PCOS

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