Interleukin News and Research

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T-cell-inducing mRNA COVID-19 vaccine improves effectiveness

Researchers develop a lipid nanoparticle-formulated mRNA-based antigen encoding three SARS-CoV-2 peptides derived from non-structural proteins.

25 May 2023

COVID-19 'bites the apple': Abdominal obesity ignites cytokine storm

Abdominal obesity increases the risk of severe COVID-19 and mortality due to heightened inflammatory responses, according to a study on Japanese patients and a murine COVID-19 model. Blocking inflammatory cytokines and preventing obesity may improve survival rates.

24 May 2023

National-level comprehensive mapping of high-fatality SARS-CoV-2 outbreaks in nursing homes

Researchers analyzed data from three SARS-CoV-2 outbreaks among nursing homes in Belgium.

24 May 2023

Study shows the potential of TAp63 as a new therapeutic target for rheumatoid arthritis

Rheumatoid arthritis (RA) is an autoimmune disease characterized by joint deterioration. The clinical outcomes of patients with active RA can be improved using anti-rheumatic medications, such as methotrexate (MTX).

22 May 2023

The role of RNA splicing in one of the deadliest forms of pancreatic cancer

In this interview, we spoke to Adrian Krainer, a Professor at Cold Spring Harbor Laboratory, about his latest research into the role of RNA splicing in one of the deadliest forms of pancreatic cancer.

22 May 2023

Cross-reactivity between Epstein-Barr virus and protein in multiple sclerosis sheds light on disease development

Research uncovers the association between multiple sclerosis (MS) and antibody reactivity to specific amino acids in CRYAB, along with the increased risk when combined with high EBNA1 responses. The study provides evidence of antibody and T cell cross-reactivity between EBNA1 and CRYAB, highlighting the role of EBV adaptive immune responses in MS development.

21 May 2023

Phase 1 clinical trial of CAR-NKT cell therapy shows promising results in neuroblastoma patients

Researchers at Baylor College of Medicine/Texas Children's Cancer Center and collaborating institutions report interim results from a first-in-human phase 1 clinical trial evaluating the safety, antitumor activity and immunological characteristics of a genetically engineered natural killer T (NKT) cell immunotherapy for neuroblastoma, a childhood tumor that most commonly arises in the adrenal gland.

15 May 2023

Analyzing impact of phospholipase D on the host immune response to A. fumigatus infection

Announcing a new article publication for Zoonoses journal. Aspergillus fumigatus infection in the lungs is accompanied by the recruitment of innate immune cells, phagocytosis, and the release of inflammatory factors.

11 May 2023

COVID-19 infection may promote aortic aneurysms and new treatment may slow its growth

The intravenous delivery of immune-modulating cells may someday slow the expansion of bulges in the aorta, known as abdominal aortic aneurysms.

10 May 2023

Menthol inhalation improves cognitive ability in animal models of Alzheimer's disease

Researchers from Cima University of Navarra (Spain) have shown in animal models of Alzheimer's disease that inhaling menthol improves cognitive ability.

10 May 2023

The potential variations in sperm quality of infertile patients during the COVID-19 pandemic

A recent study investigated how SARS-CoV-2 infection affected the semen quality of infertile men in Tunisia.

10 May 2023

New study finds elevated inflammatory cytokines and lymphocytes linked to rare cases of myocarditis after COVID-19 vaccination

Researchers investigated a cohort of patients who developed myocarditis after SARS-CoV-2 mRNA vaccination.

10 May 2023

Boosting gut health with short-chain fatty acids

Research paper provides an overview of short-chain fatty acids (SCFAs) and their role in regulating gut homeostasis. It also discusses SCFA-producing bacteria and potential therapeutic approaches to boost SCFA levels in the gut to treat related diseases.

9 May 2023

UCF researcher develops a new, more precise treatment for acute respiratory viral infections

A University of Central Florida College of Medicine researcher has developed a new, more precise treatment for a major cause of illness around the world each year -; acute respiratory viral infections.

9 May 2023

Can intermittent fasting tackle obesity-related inflammation?

Research reviews the effects of two forms of intermittent fasting, time-restricted eating (TRE) and alternate-day fasting (ADF), on body weight and key circulating inflammatory markers (CRP, TNF-alpha, and IL-6) in adults with obesity. The results suggest that intermittent fasting has little or no effect on key inflammatory markers, but more research is needed to confirm these findings.

8 May 2023

Interleukin News and Research

T-cell-inducing mRNA COVID-19 vaccine improves effectiveness

COVID-19 'bites the apple': Abdominal obesity ignites cytokine storm

National-level comprehensive mapping of high-fatality SARS-CoV-2 outbreaks in nursing homes

Study shows the potential of TAp63 as a new therapeutic target for rheumatoid arthritis

The role of RNA splicing in one of the deadliest forms of pancreatic cancer

Cross-reactivity between Epstein-Barr virus and protein in multiple sclerosis sheds light on disease development

Phase 1 clinical trial of CAR-NKT cell therapy shows promising results in neuroblastoma patients

Analyzing impact of phospholipase D on the host immune response to A. fumigatus infection

COVID-19 infection may promote aortic aneurysms and new treatment may slow its growth

Menthol inhalation improves cognitive ability in animal models of Alzheimer's disease

The potential variations in sperm quality of infertile patients during the COVID-19 pandemic

New study finds elevated inflammatory cytokines and lymphocytes linked to rare cases of myocarditis after COVID-19 vaccination

Boosting gut health with short-chain fatty acids

UCF researcher develops a new, more precise treatment for acute respiratory viral infections

Can intermittent fasting tackle obesity-related inflammation?

Mount Sinai researchers identify a new therapeutic target for MS and other brain disorders

Advancing the development of vaccines through recombinant technology

Does stress increase biological age?

Can smoking cigarettes alter your bone structure?

Study identifies immune signature to predict severe COVID-19 in cardiovascular patients

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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