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Psoriasis vs. atopic dermatitis: New study reveals surprising inflammatory differences in age-specific groups

The hematological parameters and serum biomarkers of inflammation and immunity in patients with atopic dermatitis and psoriasis.

12 Sep 2023

Low-molecular weight human interleukin-1β antagonist discovered

Researchers described the detection of a human interleukin-1β antagonist with low molecular weight that disrupts interactions with the interleukin-1 receptor type I receptor.

11 Sep 2023

Mediterranean diet supercharges skin treatment, clears up atopic dermatitis in teen

Study reports on a 14-year-old boy with atopic dermatitis who experienced complete symptom resolution after combining monoclonal antibody treatment with a Mediterranean diet. Highlighting the role of diet in managing inflammatory skin conditions, the case study suggests the therapeutic potential of integrating dietary changes with medical treatment for improved outcomes.

10 Sep 2023

Is DNA methylation the missing link in diagnosing and treating psoriasis and psoriatic arthritis?

Researchers across Europe have delved into the DNA methylation patterns in CD4+ T-cells of psoriasis and psoriatic arthritis (PsA) patients, unveiling potential new biomarkers for these conditions. Their study suggests that these unique profiles could serve as both diagnostic and prognostic tools, although further validation is needed for real-world clinical application.

10 Sep 2023

New way to administer CAR-T-cell therapy could lead to fewer side effects

When Richard O'Neil, Ph.D., joined MUSC Hollings Cancer Center two years ago, he knew that he wanted to continue finding ways to make CAR-T-cell therapy easier on patients.

8 Sep 2023

The role of exercise-induced hormone irisin in amyloid beta reduction

Researchers explored the biological mechanisms by which exercise-induced irisin attenuates amyloid-beta pathology in Alzheimer’s disease.

8 Sep 2023

Senolytic therapy in mild Alzheimer’s disease shows safety in phase I trial

Researchers conducted the phase 1 trial of orally-administered senolytic therapy comprising quercetin (Q) and dasatinib (D) for symptomatic and early-stage Alzheimer's disease (AD) patients.

8 Sep 2023

Chronic inflammation's influence on TP53 mutations in leukemia evolution explored in new study

Researchers performed a multi-omics evaluation of HSPCs obtained from individuals with myeloproliferative neoplasms transforming to TP53-related secondary forms of acute myeloid leukemia.

7 Sep 2023

Early viral exposure in mice weakens vaccine response, raising questions for human studies

Researchers at Washington University have demonstrated that early life exposure to multiple viruses in house mice dampens the immune response to SARS-CoV-2 vaccinations later in life. The study raises concerns about the applicability of common mouse models in immunological research, suggesting that prior pathogen exposure could be a significant variable in predicting vaccine efficacy.

5 Sep 2023

Biomarkers unveil insights into post-COVID-19 syndrome variability

Researchers studied a prospective observation cohort of patients with post-coronavirus disease 2019 syndrome.

1 Sep 2023

Can the consumption of colorful fruits and vegetables improve the management of gestational diabetes?

A new paper explores the dietary effects of consuming colorful fruits and vegetables (CFV).

1 Sep 2023

Study shows strong link between depression and inflammation in obese patients before and after bariatric surgery

Research funded by the National Institute for Health and Care Research (NIHR) has shown that higher levels of inflammation in the blood of patients with obesity undergoing bariatric surgery predicts poorer weight loss six months after the procedure.

31 Aug 2023

Unlocking tumor immune evasion: IL1RL1+ Treg cells and CAFs collaborate for immunotherapy resistance

Researchers demonstrated that the crosstalk between IL1RL1+ regulatory T-cells (Treg) and cancer-associated fibroblasts (CAFs) drives the tissue repairing.

30 Aug 2023

ARAMIS trial finds no benefit of anakinra in acute myocarditis

The largest randomized controlled trial of patients with acute myocarditis has found that anakinra is safe but does not reduce complications. The late breaking research presented in a Hot Line session today at ESC Congress 2023.

29 Aug 2023

Non-alcoholic steatohepatitis progression blocked by ginger essential oil

Researchers explore the potential utility of ginger essential oil in preventing NASH.

29 Aug 2023

Can the fermentation of foods enhance their antioxidant properties?

In a recent editorial published in Fermentation, researchers highlighted the use of fermentation as a means to increase the antioxidant potential of foods.

29 Aug 2023

Study unveils previously unknown urinary biomarkers, revolutionizing early detection and treatment of viral infections like COVID-19

This recent study identifies new urinary biomarkers for detecting acute COVID-19 using spectroscopic analysis. The findings reveal that these biomarkers could offer valuable tools for early diagnosis, understanding the severity of the disease, and possibly contribute to endogenous immunological defense mechanisms against SARS-CoV-2.

29 Aug 2023

The potential of gut-microbiota-targeted reprogramming interventions designed to prevent the onset and progression of cardiovascular diseases

Researchers discuss the potential of probiotic- and prebiotic-based interventions for managing cardiovascular diseases.

28 Aug 2023

Small molecule inhibitor of the NLRP3 inflammasome for treating autoinflammatory diseases

Researchers described the preclinical profile of JT002, a novel and orally bioavailable small molecule inhibitor of the NLRP3 inflammasome.

24 Aug 2023

Differences in immune responses to IL-6 inhibition therapy between male and female COVID-19 patients

Researchers investigated whether anti‑interleukin 6 monoclonal antibodies were related to heterogenous treatment effects between male and female COVID-19 patients.

24 Aug 2023

Interleukin News and Research

Psoriasis vs. atopic dermatitis: New study reveals surprising inflammatory differences in age-specific groups

Low-molecular weight human interleukin-1β antagonist discovered

Mediterranean diet supercharges skin treatment, clears up atopic dermatitis in teen

Is DNA methylation the missing link in diagnosing and treating psoriasis and psoriatic arthritis?

New way to administer CAR-T-cell therapy could lead to fewer side effects

The role of exercise-induced hormone irisin in amyloid beta reduction

Senolytic therapy in mild Alzheimer’s disease shows safety in phase I trial

Chronic inflammation's influence on TP53 mutations in leukemia evolution explored in new study

Early viral exposure in mice weakens vaccine response, raising questions for human studies

Biomarkers unveil insights into post-COVID-19 syndrome variability

Can the consumption of colorful fruits and vegetables improve the management of gestational diabetes?

Study shows strong link between depression and inflammation in obese patients before and after bariatric surgery

Unlocking tumor immune evasion: IL1RL1+ Treg cells and CAFs collaborate for immunotherapy resistance

ARAMIS trial finds no benefit of anakinra in acute myocarditis

Non-alcoholic steatohepatitis progression blocked by ginger essential oil

Can the fermentation of foods enhance their antioxidant properties?

Study unveils previously unknown urinary biomarkers, revolutionizing early detection and treatment of viral infections like COVID-19

The potential of gut-microbiota-targeted reprogramming interventions designed to prevent the onset and progression of cardiovascular diseases

Small molecule inhibitor of the NLRP3 inflammasome for treating autoinflammatory diseases

Differences in immune responses to IL-6 inhibition therapy between male and female COVID-19 patients

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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