Interleukin 2 News and Research

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Selenium as therapy for prostate cancer

Selenium may offer an intervention strategy for the treatment of prostate cancer according to results of a study from the laboratory of Allen Gao, PhD, which will be presented by Yan Hu, PhD, Departments of Medicine and Pharmacology and Therapeutics, Roswell Park Cancer Institute (RPCI) at the 2007 centennial meeting of the American Association for Cancer Research (AACR), April 14-18, in Los Angeles, CA.

17 Apr 2007

Expression Genetics completes phase I trial of lead drug candidate, EGEN-001

Expression Genetics, Inc., has announced the completion of a Phase I clinical study evaluating the Company's lead drug candidate, EGEN-001.

17 Apr 2007

Efficacy of Guanilib confirmed for inflammatory bowel disease

Callisto Pharmaceuticals has announced additional data confirming efficacy of Guanilib, a first-in-class compound currently being developed for the treatment of inflammatory bowel disease (IBD), in two different standard animal models of experimental colitis.

7 Apr 2007

We need to balance out our intake of omega-6 and omega-3 fatty acids

A new study suggests that people whose diets contain dramatically more of one kind of polyunsaturated fatty acid than another may be at greater risk for both clinical depression and certain inflammatory diseases.

3 Apr 2007

Body uses a 'dual key' system to secure immune system

"Dual key" activation, in which two people must act in concert to launch a weapon, is often installed to safeguard highly destructive arms.

2 Apr 2007

Chemoimmunotherapy versus chemotherapy for metastatic malignant melanoma

The addition of immunotherapy to chemotherapy for malignant skin cancer that has spread does not improve survival rates, researchers have found, and patients have more serious side effects, such as anemia, when the two treatments are combined.

1 Mar 2007

Vaccine against group B Streptococci

The search for a vaccine against group B streptococci Group B streptococci are one of the leading causes of infection in newborn infants, causing pneumonia, septicaemia or meningitis.

12 Feb 2007

High-dose progesterone treatment helps at-risk pregnant women avoid premature delivery

In this study, 45 women who experienced premature labor (before 37 weeks gestation) were randomly divided into treatment and observation groups. The treatment group received twice-weekly 341-mg doses of progesterone until week 36.

11 Feb 2007

Gums produce substances that lead to degeneration of the jawbone

Our gums' own cells produce the substances that lead to the degeneration of the jawbone. This is one of the findings in a dissertation that Py Palmqvist defended at Umea University in Sweden recently.

24 Jan 2007

Interleukin-13 receptor-targeted nanovesicles are a potential therapy for glioblastoma multiforme

Glioblastoma multiforme is among the most aggressive and difficult cancers to treat. Now, researchers at Penn State University have shown that a lipid-based nanoparticle, designed to bind to a specific receptor found on malignant brain cells but not healthy ones, improves the potency of a common anticancer drug and slows significantly the growth of glioblastoma in mice.

8 Jan 2007

New cancer treatments use body's own immune system to kill melanoma tumours

Scientists are claiming that the body's own immune system could be used to fight the most serious form of skin cancer, malignant melanoma.

13 Nov 2006

High levels of two proteins in the bloodstream indicate need for action to avoid heart attack

Researchers working to decode chemical SOS signals sent out by disease-damaged hearts believe they now know better when to aggressively clear clogged arteries and when medical procedures may be unnecessary and even harmful.

12 Sep 2006

Individuals with major depression have an exaggerated inflammatory response to psychological stress

Individuals with major depression have an exaggerated inflammatory response to psychological stress compared to those who do not suffer from depression, according to a study by researchers at Emory University School of Medicine.

4 Sep 2006

Induction of potent antitumor immunity by intratumoral injection of IL-23 transduced dendritic cells

One therapy for treating brain tumors alerts the immune system to the presence of foreign material. A second therapy enhances the first and prolongs the immune system's response.

4 Sep 2006

Scientists create tumour zapping T cells which knock out cancer

Scientists in the United States have genetically engineered normal immune cells to become specialized fighters and used them to attack cancerous tumours.

31 Aug 2006

Trying to improve on the activity of Interferon-Alpha in metastatic renal cell carcinoma

Interferon-alpha (IFN) has been a mainstay in the systemic treatment of metastatic renal cell carcinoma (RCC) for decades, with response rates ranging from 3-15%.

16 Aug 2006

Drug trial fiasco induced immune system overload in patients

The doctors who treated six British men in a trial of a drug in March which went horribly wrong, say they believe the men suffered an immune system overreaction known as a cytokine storm.

15 Aug 2006

Interleukin 21 may enhance the effectiveness of Herceptin

Preliminary research suggests that a drug that targets a particular type of breast cancer might be more effective if patients are also given a substance made by the body that stimulates certain immune cells.

6 Aug 2006

A tipple a day keeps heart attacks away

Researchers say that seniors who have a drink each day may live longer and suffer fewer heart problems than teetotalers do, but they are not sure why.

27 Jul 2006

Reduced levels of antiinflammatory cytokines in patients with chronic widespread pain

Chronic widespread pain, a common medical condition, can be difficult to treat and is often associated with fatigue, poor sleep and depression.

26 Jul 2006