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SARS-CoV-2's resistance to remdesivir in vitro

A new preprint research paper posted to the bioRxiv server discusses the emergence of mutations in the SARS-CoV-2 virus, allowing it to escape the effects of the most commonly used antiviral drug, remdesivir.

14 Feb 2021

Specific SARS-CoV-2 genomic variations are associated with higher COVID-19 deaths

A team of scientists from South Korea and the United States has conducted an interesting study to investigate whether mutations in the genome of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can affect the severity of coronavirus disease 2019 (COVID-19). The study findings reveal that mutations in the viral spike protein and RNA polymerase complex can increase the risk of COVID-19 mortality.

25 Nov 2020

Adaptations found in RNA secondary structure in genes of two proteins of SARS-CoV-2

To investigate mutations in coronaviruses, a new study by scientists at Duke University and published on the preprint server bioRxiv, used a computational methodology, adaptiPhy, which identifies extra nucleotide substitutions in certain parts of the viral genome compared to mutations that have no effect on the genome.

18 Sep 2020

UQ researchers reveal three-dimensional structure of important enzyme

Advanced herbicides and treatments for infection may result from the unravelling of a 50-year-old mystery by University of Queensland researchers.

11 Jul 2020

Unique mutations could weaken Indian SARS-CoV-2 strain

A new study published on the preprint server bioRxiv in June 2020 suggests that the presence of unique mutations in the viral strains circulating in India has led to their attenuation.

9 Jun 2020

Specialized proteins could soak up excess cytokines in COVID-19 patients

One of the defining features of Covid-19 is the excessive immune response that can occur in severe cases. This burst of immune overreaction, also called a cytokine storm, damages the lungs and can be fatal.

16 Apr 2020

Study provides new insight into neurofibromin-deficient ER+ breast cancer

An international team of researchers led by scientists at Baylor College of Medicine has new insights into the function of neurofibromin, a tumor suppressor produced by the NF1 gene.

5 Mar 2020

Nanopores – the key to identifying amino acids in proteins

DNA and RNA sequencing has become the new watchword for the biological researchers, as this tells them exactly what is going on at cellular level in health and disease. However, it is a partial revelation unless we also know what is happening at the level of proteins as well.

19 Dec 2019

Scientists discover how brown fat may help protect against obesity and diabetes

Rutgers and other scientists have discovered how brown fat, also known as brown adipose tissue, may help protect against obesity and diabetes.

21 Aug 2019

Research findings could help identify Alzheimer's patients who will benefit from exercise

A novel study has discovered metabolites that predict which Alzheimer's patients are likely to see their symptoms improve with exercise therapy.

6 Aug 2019

Protein supplements containing BCAA may have ‘detrimental effects’ on health and lifespan

New research suggests that BCAAs in the form of pre-mixed protein powders, shakes and supplements may do more harm to health than good.

1 May 2019

Ensuring 100% Accuracy in Antibody Protein Sequencing

The purpose of antibody protein sequencing is to accurately deduce every single amino acid present in the primary sequence. This is an issue with isoleucine and leucine which have the same molecular weight. Rapid Novor has developed a technique to determine these with 100% accuracy.

From Rapid Novor Inc 16 Apr 2019

Fasting may boost human metabolic activity, research suggests

Fasting may help people lose weight, but new research suggests going without food may also boost human metabolic activity, generate antioxidants, and help reverse some effects of aging.

31 Jan 2019

A Single Platform to Sequence All Monoclonal Antibody Proteins

Having a single platform to sequence all monoclonal antibody proteins provides researchers with key information for research, development and drug discovery

From Rapid Novor Inc 3 Oct 2018

Paracetamol use in infancy may increase risk of developing asthma by the age of 18

Children who take paracetamol during their first two years of life may be at a higher risk of developing asthma by the age of 18, especially if they have a particular genetic makeup, according to new research presented at the European Respiratory Society International Congress today.

17 Sep 2018

Metabolic signatures in blood may help in earlier diagnosis of autism, shows research

Metabolic signatures in the blood of children with autism spectrum disorder may lead to earlier diagnosis of the condition for some children, according to newly published research. These biochemical signatures provide insight into how the body metabolizes certain amino acids important to typical neurodevelopment.

6 Sep 2018

Research identifies new biomarkers for future dementia risk

Sudha Seshadri, M.D., founding director of the Glenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases at UT Health San Antonio, is co-leader and senior author on research announced March 6 that identifies novel biomarkers of risk for future dementia.

6 Mar 2018

Deciphering Antibodies with Next-Generation Protein Sequencing Technology

Mr. Mingjie Xie, MSc, MBA, is the co-founder and CEO of Rapid Novor Inc. He is a computer scientist by training andreceived his MSc degree from Western University in the field of bioinformatics. He received his MBA degree from Richard Ivey School of Business to pursue his interests in business. Prior to co-founding Rapid Novor Inc, Mingjie is the COO of a bioinformatics software company.

From Rapid Novor Inc 9 Jan 2018

Diabetes drug metformin could help reduce toxic acid levels linked to MSUD

Maple Syrup Urine Disease (MSUD) is a rare inherited metabolic disorder involving the dysfunction of an enzyme which breaks down three essential amino acids: leucine, isoleucine and valine.

6 Jul 2016

Food-based proteins can help address child malnutrition in developing countries

Contrary to popular belief among world relief workers, children in developing countries may not be eating enough protein, which could contribute to stunted growth, a Johns Hopkins-directed study suggests.

24 Feb 2016