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TB screening needed for people on methotrexate who live in at-risk areas

New research presented at ACR Convergence, the American College of Rheumatology's annual meeting, shows that tuberculosis (TB) screening and ongoing clinical care is needed for people on methotrexate who live in areas where the highly infectious illness is common.

6 Nov 2020

WHO welcomes SHINE trial results on shorter treatment for drug-susceptible TB in children

The World Health Organization's Global TB Programme welcomes the results from an important study on shortened treatment for drug-susceptible tuberculosis in children, presented at the 51st virtual Union World Conference on Lung Health.

2 Nov 2020

NTU-incubated start-up plans clinical trial of new slow-release pill for Parkinson’s disease

Materials scientists from Nanyang Technological University, Singapore (NTU Singapore) have developed a new pill which uses the stomach as a drug reservoir and delivers medicines slowly over time to patients with Parkinson's disease (PD).

16 Sep 2020

New recommendations to tackle tuberculosis amid coronavirus crisis

The World Health Organization has today issued new recommendations to tackle tuberculosis, a respiratory disease, in the wake of coronavirus spreading across continents.

25 Mar 2020

Combination of two antibiotics eradicates latent tuberculosis in macaques

A major goal of tuberculosis (TB) research is to find a way to treat people with the latent (or inactive) form of the disease to keep them from developing symptomatic TB.

17 Dec 2019

New clinical guideline for treatment of drug-resistant tuberculosis published

The American Thoracic Society, Centers for Disease Control and Prevention, European Respiratory Society and the Infectious Diseases Society of America have published an official clinical guideline on the treatment of drug-resistant tuberculosis in the Nov. 15 American Journal of Respiratory and Critical Care Medicine.

18 Nov 2019

New sensor technology to revolutionize treatment and cure of tuberculosis

A trial involving an edible sensor connected to a paired mobile, that enables medical staff to remotely see patients` intake of tuberculosis (TB) medicine, has produced superior results to directly observed therapy (DOT), where a healthcare worker watches the patient swallow medication, leading researchers to suggest that the technology could be a game changer in high prevalence countries where treatment adherence remains a stumbling block to eliminating TB.

4 Oct 2019

Tuberculosis still looms large over a fourth of the world’s people

A new Danish study concludes that a quarter of the people on earth have the tuberculosis bacillus within their bodies. This disease preys on over 10 million people annually, and kills 2 million a year. It is Number 1 on the list of killer diseases, far above AIDS and other infections.

5 Aug 2019

Large prevention trial launched for people exposed to multidrug-resistant tuberculosis

A large clinical trial to assess treatments for preventing people at high risk from developing multidrug-resistant tuberculosis has begun.

25 Jun 2019

Reversing drug resistance in tuberculosis bacteria

About 1.5 million people died of tuberculosis (TB) in 2017, making it the most lethal infectious disease worldwide. A growing rise in drug-resistant TB is a major obstacle to successfully treating the illness.

4 Jun 2019

New approach to identify faster, more effective TB drug treatment regimens

Tuberculosis is a potentially deadly though curable disease. Each year about 10 million people develop active cases, and 1.6 million people die. In addition, about 1.7 billion people around the world are infected with TB bacteria, which can lie dormant for weeks to years, then become active and cause disease in up to 10 percent of those who are infected.

15 May 2019

Novel models and strategies for TB detection, elimination, and care

This week, publication of a special issue on tuberculosis begins in PLOS Medicine, advised by guest editors Richard Chaisson of Johns Hopkins University, Claudia Denkinger of the University of Heidelberg, and Mark Hatherill of the South African Tuberculosis Vaccine Institute.

8 Apr 2019

Improved TB Diagnostic Assay for Better Multiplexing from Bruker

In time for the World Tuberculosis (TB) Day 2019 on Sunday, March 24th, Bruker today announced the launch of an important further innovation in the field of tuberculosis diagnostics.

From Bruker BioSpin - NMR, EPR and Imaging 26 Mar 2019

Anti-TB drugs can increase susceptibility to Mtb reinfection

Current treatments for tuberculosis are very effective in controlling TB infection caused by Mycobacterium tuberculosis. They don't, however, always prevent reinfection. Why this happens is one of the long-standing questions in TB research.

22 Mar 2019

Johns Hopkins researchers to present latest findings on TB and HIV at CROI 2019

Johns Hopkins Medicine researchers are attending the annual Conference on Retroviruses and Opportunistic Infections, where they are sharing their latest findings in the ongoing battle against HIV/AIDS and related infectious diseases with other top basic, translational and clinical researchers from around the world.

7 Mar 2019

Peptide derived from fungi prevents growth of tuberculosis bacteria

The discovery of the peptide as a possible future antibiotic was made when the researchers screened different antimicrobial peptides' ability to prevent the growth of the tuberculosis bacteria Mycobacterium tuberculosis.

4 Mar 2019

Study finds high prevalence of TB infection among Tibetan refugee schoolchildren

In a tuberculosis screening and treatment initiative covering the entire population of Tibetan refugee schoolchildren in northern India, a team directed by researchers at Johns Hopkins Medicine and the University of Wisconsin says it has found not only a startlingly high prevalence of TB disease and infection, but also a potentially workable strategy to eliminate the disease in a large, high-risk group.

19 Dec 2018

Researchers use new methods to optimize treatments for tuberculosis meningitis

Although relatively rare in the United States, and accounting for fewer than 5 percent of tuberculosis cases worldwide, TB of the brain--or tuberculosis meningitis (TBM)--is often deadly, always hard to treat, and a particular threat to young children.

6 Dec 2018

TB Alliance initiates SimpliciTB to test if new four-drug regimen can treat most types of tuberculosis

TB Alliance has initiated a pivotal clinical trial, SimpliciTB, that will evaluate whether a new four-drug regimen can treat most types of tuberculosis including multidrug-resistant TB more quickly and effectively than currently-available treatments.

28 Aug 2018

Children with multidrug-resistant tuberculosis have successful treatment outcomes, study shows

The results of a large, international systematic review published in the journal PLOS Medicine show that tuberculosis treatment is successful in children with multidrug-resistant tuberculosis. The study was used to inform the World Health Organization guidelines on treatment of MDR-TB in children.

21 Aug 2018