Joint Pain News and Research

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Ibrutinib highly active and well tolerated in patients with chronic lymphocytic leukemia

Updated results from a Phase Ib/II clinical trial indicates that a novel therapeutic agent for chronic lymphocytic leukemia (CLL) is highly active and well tolerated in patients who have relapsed and are resistant to other therapy.

11 Dec 2012

Natural product to combat menopause symptoms

Menopause is a time of great changes for most women, but information about this change of life is often sparse and contradictory. Options for symptom relief are limited. Natural products can be a healthier alternative and can provide symptom relief

10 Dec 2012

Physician's Technology launches WilloMD iLaserX device

The Italian Renaissance sculptor Michelangelo once declared "everything hurts". Baby boomers are more active than ever and stress their joints. Millions rely on dangerous pain meds and injections to stay active. Pain medication and injections can be dangerous and even lethal. Popular therapeutic pain laser technology offers hope but is not practical for home use and is out of reach of a vast patient population.

10 Dec 2012

Ibrutinib may effectively combat chronic lymphocytic leukemia

The promising investigational targeted therapy ibrutinib and its mechanism of silencing gene communication pathways critical to the development of cancer may be an effective way to combat chronic lymphocytic leukemia (CLL), according to studies presented today at the 54th Annual Meeting of the American Society of Hematology (ASH).

10 Dec 2012

Guineafowl may spread Crimean-Congo hemorrhagic fever virus

Turkey raises and releases thousands of non-native guineafowl to eat ticks that carry the deadly Crimean-Congo hemorrhagic fever virus. Yet research suggests guineafowl eat few ticks, but carry the parasites on their feathers, possibly spreading the disease they were meant to stop, says a Turkish biologist working at the University of Utah.

30 Nov 2012

Two-route drug combination best for horse joint pain

A combination of systemic nonsteroidal anti-inflammatory drugs plus intrasynovial glucocorticosteroids is superior to either medication alone in improving outcomes for lame horses with perisynovial pain of the metacarpophalangeal joint, report Dutch researchers.

28 Nov 2012

UGA research finds children with noncardiac chest pain have higher levels of anxiety

Psychological factors can have as much-or more-impact on pediatric chest pain as physical ones, a University of Georgia study found recently.

17 Nov 2012

Plexxikon updates Zelboraf Phase 1 data on BRAF V600E mutation-positive melanoma

Plexxikon today announced that updated Phase 1 clinical data of Zelboraf (vemurafenib) were presented at the Society for Melanoma Research (SMR) 2012 Congress, held November 8-11 in Los Angeles, CA.

8 Nov 2012

Roundup: Va. health chief quits, citing new abortion clinic regulations; Texas will shutter women's health program if Planned Parenthood participates

Virginia Health Commissioner Karen Remley resigned Thursday over new GOP-backed regulations that could shutter most Virginia abortion providers as reproductive rights take center stage in pivotal Senate and presidential races.

20 Oct 2012

Longer looks: The time is now for community health workers; Patients sharing in medical decisions; One doctor's plea for help

By the time Frederick Pegues Jr. was resting in bed at Temple University Hospital, the irony struck him hard. Here, he had just finished a month-long course in being a community health worker, sponsored by Temple University Hospital. He had learned how to help patients navigate a complicated health system. Yet he himself had not been able to get the help he needed.

5 Oct 2012

Hip implants are more likely to fail in obese people due to thigh size

University of Iowa researchers have determined that thigh size in obese people is a reason their hip implants are more likely to fail.

20 Sep 2012

Annual economic cost of chronic pain is as high as $635 billion: Study

Health economists from Johns Hopkins University writing in The Journal of Pain (www.jpain.org) reported the annual cost of chronic pain is as high as $635 billion a year, which is more than the yearly costs for cancer, heart disease and diabetes.

12 Sep 2012

Leading dengue fever vaccine candidate 30% effective in first large clinical trial

"The leading candidate to become the world's first vaccine against dengue fever was only 30 percent effective in its first large clinical trial, dealing at least a temporary setback to efforts to control a disease that threatens half the world's population," the New York Times reports.

12 Sep 2012

More patients gain weight after joint replacement surgery

Hip and knee replacements are now a common surgical procedure with more than 700,000 total joint arthroplasties (TJAs) performed in the US every year. Due to the reduction in pain and increases in mobility experienced after having a TJA, it could be expected that weight loss may occur as a by-product of the surgery.

10 Sep 2012

Astellas Pharma receives FDA approval for Xtandi to treat metastatic CRPC

The U.S. Food and Drug Administration today approved Xtandi (enzalutamide) to treat men with late-stage (metastatic) castration-resistant prostate cancer that has spread or recurred, even with medical or surgical therapy to minimize testosterone.

1 Sep 2012

Community-based pharmacists could provide added resource in identifying knee OA

Canadian researchers have determined that community-based pharmacists could provide an added resource in identifying knee osteoarthritis (OA). The study, published in Arthritis Care & Research, a journal of the American College of Rheumatology (ACR), represents the first evidence supporting a collaborative approach to managing knee OA.

28 Aug 2012

Guidelines for parents to beat back-to-school bugs

School bells are beginning to sound again across the country, so it will only be a matter of time until every parent comes face-to-face with a child who wakes up with a cold, fever or upset stomach.

24 Aug 2012

FDA warns consumers about potential health risks of two natural dietary supplements

The U.S. Food and Drug Administration today issued a new warning to consumers about the potential health risks of two products marketed as natural dietary supplements for treating arthritis, muscle pain, osteoporosis, bone cancer, and other conditions.

22 Aug 2012

Arthritis patients prioritize lifestyle intervention research

Most patients believe that research into joint pain should focus on self-management and lifestyle modifications, suggests a UK survey of older individuals with self-reported joint pain.

20 Aug 2012

Nanofiber scaffolds regenerate protein components in cartilage repair

Johns Hopkins tissue engineers have used tiny, artificial fiber scaffolds thousands of times smaller than a human hair to help coax stem cells into developing into cartilage, the shock-absorbing lining of elbows and knees that often wears thin from injury or age. Reporting online June 4 in the Proceedings of the National Academy of Sciences, investigators produce an important component of cartilage in both laboratory and animal models.

18 Jul 2012