Juvenile Arthritis News and Research

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Anti-tumor necrosis factor drugs modestly reduce risk of acute coronary syndrome

Tumor necrosis factor inhibitor drugs (commonly called Anti-TNFs) modestly reduce the risk of acute coronary syndrome, such as heart attacks and angina, in rheumatoid arthritis patients whose inflammation places them at higher risk of developing coronary heart disease, according to new research findings presented this week at the American College of Rheumatology Annual Meeting in San Diego.

28 Oct 2013

ACR journals publish guide that provides new treatments for children with systemic JIA

In the U.S., there are nearly 300,000 children with juvenile arthritis and other rheumatic illnesses according to estimates from the American College of Rheumatology (ACR). For pediatric patients with systemic juvenile idiopathic arthritis (JIA), effective treatment for this disabling disease is imperative.

24 Sep 2013

Parent's guide book for caring children living with juvenile arthritis

Parents who have children with chronic autoimmune diseases like juvenile arthritis face a lifetime of obstacles and challenges and now there's a book to help them. In Living with Juvenile Arthritis: A Parent's Guide, author Kimberly Poston Miller shares with readers her hard-earned wisdom and experiences as the mother of two children living with juvenile arthritis and a number of related autoimmune conditions.

11 Sep 2013

Researchers discover potential markers for severity of juvenile idiopathic arthritis

Children who suffer from arthritis could one day receive more targeted treatment thanks to potential markers for the severity of the disorder discovered by researchers at the University of Adelaide and Women's and Children's Hospital.

15 Jul 2013

Study: Total knee replacements in younger patients with juvenile arthritis last for 10 years

When you think of knee replacement surgery, you generally envision an older adult with painful arthritis. But the procedure is also used for younger patients with juvenile idiopathic arthritis whose joints have been severely damaged by the disease. Because the surgery in younger patients is relatively rare, little data exist on the longevity of knee replacements in JIA patients.

19 Mar 2013

Ceramic-on-ceramic hips good option for juvenile arthritis

Study results suggest that ceramic-on-ceramic artificial hip joints offer a better medium-term prognosis than metal- or ceramic-on-polyethylene joints for children with juvenile idiopathic arthritis.

18 Dec 2012

HSS announces opening of new Lerner Children's Pavilion

The new Pavilion within the #1 hospital for orthopedics in the country affirms HSS' longstanding commitment to championing children and caring for their musculoskeletal conditions.

26 Oct 2012

Ten-year-old kid to participate in annual Arthritis Walk on June 23

Ten-year-old Cheyanne Campo has achieved a lofty goal, despite - and because of - a sometimes painful disease. She has raised more than $500 for the Arthritis Foundation and will be participating in the organization's annual Arthritis Walk on June 23 in Battery Park.

23 Jun 2012

Juvenile Arthritis patients may have difficulties achieving educational success

As children with juvenile idiopathic arthritis (JIA) grow into adulthood, disability due to disease may adversely affect their ability to achieve educational success. Findings published in Arthritis & Rheumatism, a journal of the American College of Rheumatology (ACR), suggest that functional disability impacts educational attainment, which is key to successful employment in adulthood.

31 May 2012

DMARD not superior to oral therapy in long-term treatment of patients with JIA

A retrospective analysis of methotrexate (MTX) safety data found that injection of this disease-modifying anti-rheumatic drug (DMARD) was not superior to oral therapy in long-term treatment of patients with juvenile idiopathic arthritis (JIA). Findings published in Arthritis Care & Research, a peer-reviewed journal of the American College of Rheumatology (ACR), suggest that with similar efficacy and tolerability the more comfortable oral approach may be more suitable to treat pediatric arthritis patients.

30 May 2012

NHS approves new rheumatoid arthritis drug RoActemra

RoActemra, which is the first innovation in the field for ten years, is being recommended for patients who have failed on standard treatments. It is the first time RoActemra has been approved for NHS patients in England and Wales with moderate to severe rheumatoid arthritis who are at an early stage in the disease. The drug has been available for early use in Scotland for two years.

23 Feb 2012

Juvenile arthritis affected kids are at a high risk of cancer: Study

A new study shows that kids with juvenile idiopathic arthritis develop cancer four times more often than children without the disease, but the treatments they receive - including biologic treatments like Enbrel - may not explain their increased risk. If confirmed, researchers say the findings should ease fears that biologic treatments known as TNF inhibitors cause cancer in children and young adults.

14 Feb 2012

Children with polyarticular JIA benefit from early and aggressive therapy

Children with juvenile arthritis who are treated early and aggressively have better outcomes, according to research presented this week at the American College of Rheumatology Annual Scientific Meeting in Chicago.

7 Nov 2011

DMARDs appear to be more effective for children with arthritis

Medications known as disease-modifying anti-rheumatic drugs, or DMARDs, appear to be more effective than other treatments for children with arthritis, but there is not enough evidence to support one kind of DMARD over another, according to a new report from HHS' Agency for Healthcare Research and Quality.

28 Sep 2011

Novartis reports positive results from first pivotal ACZ885 Phase III trial in systemic juvenile idiopathic arthritis

Novartis announced today positive results of the first pivotal Phase III trial of ACZ885 in patients with systemic juvenile idiopathic arthritis (SJIA), a rare and serious childhood auto-inflammatory disease. The results, presented at the 2011 European Pediatric Rheumatology Congress in Bruges, Belgium, showed all primary and secondary endpoints of the study were met.

17 Sep 2011

Toclizumab for juvenile rheumatoid arthritis

The arthritis drug Toclizumab could be a boon for hundreds of children suffering from severe arthritis. It has been re-launched in children after being already licensed for the treatment of adults. At least two thirds of children taking tocizilumab have been able to return to a normal life, after many were bedridden or forced into wheelchairs by the disease, the clinical studies reveal.

16 Aug 2011

Pediatric researchers find potential tools for controlling cytokine storm

By analyzing complex interactions of the immune system in an animal study, pediatric researchers have found potential tools for controlling a life-threatening condition called a cytokine storm that may strike children who have juvenile arthritis and other autoimmune diseases.

17 May 2011

ACR releases new guidelines for JA treatment

Several Canadian pediatric rheumatologists and health professionals played a prominent role in developing new guidelines for treating juvenile arthritis.

31 Mar 2011

Early diagnosis of juvenile idiopathic arthritis critical to avoid disability, deformity

While lab tests and imaging can sometimes help diagnose juvenile idiopathic arthritis (JIA), a physical examination and thorough patient history are the most valuable tools in identifying this disease. According to a new literature review from the Journal of the American Academy of Orthopaedic Surgeons (JAAOS), the rate of false positives in laboratory evaluations and imaging studies meant to screen for juvenile arthritis makes their value limited.

3 Mar 2011

New SMILEY tool helps assess QoL of children with lupus

A newly designed tool is helping researchers shed light on the quality of life (QoL) of children with lupus around the world, according to research presented at the American College of Rheumatology (ACR) annual meeting, held Nov. 7-11, in Atlanta.

11 Nov 2010