Kawasaki Disease News and Research

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Kawasaki disease (also known as lymph node syndrome, mucocutaneous node disease, infantile polyarteritis and Kawasaki syndrome) is a disease, largely of infants, which affects many organs, including the skin, mucous membranes, lymph nodes, and blood vessel walls, but the most serious effect is on the heart where it can cause severe aneurysmal dilations.

American Heart Association report highlights disparities in heart disease, calls for equitable healthcare

The American Heart Association's report on heart disease and stroke statistics emphasizes health equity and addresses structural racism in healthcare, revealing disparities in cardiovascular risk factors and disease prevalence among different communities.

29 Jan 2024

Study discovers method to classify febrile illness with a single blood sample

Researchers trained machine learning (ML) models to analyze RNA molecular signatures in patients’ blood.

28 Aug 2023

Study reports the first protein-based diagnostic signature to discriminate MIS-C from Kawasaki Disease and other common infections

Researchers explore the distinguishing features of MIS-C as compared to other inflammatory-infectious syndromes in children.

4 Aug 2023

MIS-C in children: A distinct autoimmune response to COVID-19 unveiled

The study reveals that MIS-C patients, post SARS-CoV-2 infection, develop a unique immune response against the virus' N protein, indicating a cross-reactivity with the self-protein SNX8, which might link the infection to the ensuing inflammatory syndrome.

8 Jun 2023

Study finds biomarker pattern in children with COVID 19-linked multisystem inflammatory syndrome

Children with multisystem inflammatory syndrome (MIS-C) — a rare condition linked with the virus that causes COVID-19 — have biochemical indicators of cell injury and cell death that are distinct from other children with COVID-19, according to a study funded by the National Institutes of Health.

25 Apr 2023

Is there an association between COVID-19 and the risk of developing an autoimmune disease?

Researchers reviewed data on the incidence of autoimmune diseases in the post-acute coronavirus disease 2019 period.

17 Apr 2023

An extremely rare case report of rebound multi-system inflammatory syndrome in children

Researchers described the case report of an infant boy experiencing rebound MIS-C.

12 Apr 2023

Delayed presentation of MIS-C following COVID-19

Researchers elucidate the pathophysiology of MIS-C and describe the probable reasons for the delayed presentation of the condition following COVID-19.

15 Feb 2023

Rockefeller scientists describe the genetics of severe SARS-CoV-2 infection in children

One of the most terrifying aspects of the COVID pandemic has been its unpredictably severe impact on some children.

10 Feb 2023

Study finds fewer cases of MIS-C during omicron wave of the pandemic than delta

A new University at Buffalo study conducted at John R. Oishei Children's Hospital is one of the first to reveal that there were fewer cases of multi-system inflammatory syndrome in children (MIS-C) during the omicron wave of the pandemic than the delta wave.

19 Jan 2023

2022: a year in MIS-C research

In a recent review published in Nature Reviews Rheumatology, researchers reviewed existing data on the multisystem inflammatory syndrome in children (or MIS-C).

11 Jan 2023

NIH awards eight research grants to advance diagnosis of Multisystem Inflammatory Syndrome in Children

The National Institutes of Health has awarded eight research grants to refine new technologies for early diagnosis of severe illnesses resulting from SARS-CoV-2 infection in children.

9 Jan 2023

New tool may help better predict resistance to immunoglobulin therapy among children with Kawasaki disease

predict resistance to immunoglobulin therapy among children with Kawasaki disease in the United States.

2 Dec 2022

Researchers explore single-cell sequencing technologies to understand molecular mechanisms of autoimmune diseases

A new review discussed the applications of single-cell ribonucleic acid sequencing (scRNA-seq) in understanding autoimmune disorders.

17 Oct 2022

Could COVID-19 infections trigger a relapse of mycosis fungoides or other cutaneous T-cell lymphomas?

Recently, authors highlighted the potential role of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections in triggering the relapse of mycosis fungoides, a type of cutaneous T-cell lymphoma.

17 Oct 2022

Review of COVID-19 in children before and after SARS-CoV-2 Delta and Omicron variant emergence

Researchers provided a summary of SARS-CoV-2 infections among children pre- and post-SARS-CoV-2 Delta and Omicron variants of concern (VOCs) emergence.

12 Sep 2022

Persistent viral infections within hosts cause post-acute sequelae of COVID-19, research shows

A research team, comprised of Associate Professor Tomonari Sumi of the Research Institute for Interdisciplinary Science at Okayama University and Associate Professor Kouji Harada of the Center for IT-based Education at Toyohashi University of Technology, has developed a mathematical model of the immune response within infected hosts that considers systemic infection of a novel coronavirus (SARS-CoV-2), and demonstrated by conducting experimental computer simulations that persistent viral infections within hosts potentially cause long COVID or post-acute sequelae of COVID-19.

3 Aug 2022

Overlap in pro-inflammatory genes and pathways between COVID-19 and MIS-C

In a recent study posted to the medRxiv* pre-print server, researchers in the United States characterized differential host immune responses in acute coronavirus disease 2019 (COVID-19) and multisystem inflammatory syndrome in children (MIS-C) to inform future development of novel biomarkers for both diseases.

23 Jun 2022

The impact of SARS-CoV-2 linkage on outcomes in hospitalized children with PIMS across Canada

Researchers analyze the clinical effects and implications of SARS-CoV-2 infection in children who were hospitalized due to MIS-C.

1 Jun 2022

Is type 1 diabetes likely to rise after the COVID pandemic?

A recent article posted to the journal Diabetes/Metabolism Research and Reviews explored the risk of a type 1 diabetes wave after the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic.

6 May 2022