Kawasaki Disease News and Research

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Kawasaki disease (also known as lymph node syndrome, mucocutaneous node disease, infantile polyarteritis and Kawasaki syndrome) is a disease, largely of infants, which affects many organs, including the skin, mucous membranes, lymph nodes, and blood vessel walls, but the most serious effect is on the heart where it can cause severe aneurysmal dilations.

GlobalData: Further research into MIS-C could reveal how COVID-19 affects the immune system

Some children have developed a severe inflammatory response due to COVID-19 infection that appears similar to Kawasaki disease.

22 Jun 2020

GlobalData: COVID-19 effects on pregnancy remain uncertain and debatable

A recent research study showed that for 16 COVID19 positive women there were evidences that their placentas had blood clots and indications of abnormal blood flow from the mother to the baby with most of the women having normal pregnancies.

12 Jun 2020

New syndrome associated with SARS-CoV-2 is new and distinct from Kawasaki disease

A study on children suffering from severe inflammatory symptoms shows the condition is new and distinct from Kawasaki disease.

8 Jun 2020

Improving detection of SARS-CoV-2 infection among severely ill children

Researchers in the UK have conducted a study showing that children with a severe inflammatory syndrome had high levels of antibodies against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), despite having tested negative for the virus by polymerase chain reaction (PCR).

8 Jun 2020

Kawasaki-like inflammatory syndrome appears to be more common in children of African ancestry

An inflammatory syndrome in children and adolescents, believed to be linked to covid-19, seems to be more common among children of African ancestry, finds a small study from a hospital in Paris, published by The BMJ today.

3 Jun 2020

Rare deadly disease linked to coronavirus infection seen in children

Now, new evidence has shown that children with coronavirus disease (COVID-19) experience a Kawasaki-like illness, called multisystem inflammatory syndrome in children (MIS-C). The complication is akin to toxic shock syndrome, a condition that occurs due to sepsis. Though rare, the condition is life-threatening.

29 May 2020

Teens develop septic shock due to COVID-19

Since the emergence of the novel coronavirus disease (COVID-19), most people who develop severe illness are older adults, those with underlying medical conditions, and those who are immunocompromised. Though children are mostly spared, some adolescents developed septic shock due to COVID-19, a new study has found.

24 May 2020

Study presents early data on SARS‐CoV ‐2 testing, outcomes at Australian children’s hospital

In the first 30 days since seeing their first patient, the number of children testing positive to COVID-19 at an Australian tertiary pediatric hospital has been low and none who contracted the virus required in-hospital treatment, according to a new study.

21 May 2020

FDA approves IND application by Octapharma USA for severe COVID-19 patients

The U.S. Food and Drug Administration (FDA) has approved the investigational new drug (IND) application submitted by Octapharma USA for a phase three clinical trial on the efficacy and safety of Octagam 10% [Immune Globulin Intravenous (Human)] therapy in COVID-19 patients with severe disease progression.

20 May 2020

Immunotherapy, steroids restore heart function in children with COVID-related multi-system inflammatory syndrome

Treatment with antibodies purified from donated blood - immune globulin therapy - and steroids restored heart function in the majority of children with COVID-related multi-system inflammatory syndrome, according to new research published yesterday in Circulation, the flagship journal of the American Heart Association.

19 May 2020

Steroids and immunotherapy improve outcomes in children with COVID-related multi-system inflammatory syndrome

19 May 2020

Kawasaki disease outbreak in children with COVID-19

The ongoing COVID-19 pandemic has marched its way to almost all parts of the world, with hundreds of thousands of deaths and over 4.5 million cases as of May 15, 2020. One saving grace has been the apparent sparing of children, though the mortality in older people is quite high.

17 May 2020

Study finds children at greater risk for severe complications from COVID-19

Children, teens and young adults are at greater risk for severe complications from COVID-19 than previously thought and those with underlying health conditions are at even greater risk, according to a study coauthored by a Rutgers researcher.

11 May 2020

COVID-19 could be causing potentially fatal inflammatory disease in children, doctors warn

Since the emergence of the coronavirus disease (COVID-19) in China in December 2019, health experts have cautioned that the disease is particularly serious in high-risk populations, including older adults, those with underlying diseases, and those who are immunocompromised. Now, doctors in the United Kingdom warn of a rare and severe inflammatory disease in children with COVID-19.

28 Apr 2020

Study shows ADA2 is a sensitive, specific biomarker for macrophage activation syndrome

According to new research findings presented at the 2019 ACR/ARP Annual Meeting, adenosine deaminase 2 (ADA2) in the peripheral blood is a sensitive, specific biomarker for macrophage activation syndrome, a potentially life-threatening complication of systemic juvenile idiopathic arthritis (systemic JIA)

10 Nov 2019

As off-label use spreads, supplies of niche drugs and patients’ patience grow short

Medical treatment has knocked down tumors in 6-year-old Easton Daniels' brain, but the drug used also wiped out his immune system.

24 Sep 2019

Study provides evidence that enterovirus may be a factor in acute flaccid myelitis

A new study analyzing samples from patients with and without acute flaccid myelitis provides additional evidence for an association between the rare but often serious condition that causes muscle weakness and paralysis, and infection with non-polio enteroviruses.

13 Aug 2019

Study identifies antigens targeted by antibody response to Kawasaki Disease

A new study identifies antigens targeted by the antibody response of children with Kawasaki Disease.

29 Apr 2019

Kawasaki disease may be triggered by a combination of environmental factors

A new study has found that Kawasaki disease (KD) is not caused by one single factor but has multiple environmental triggers.

12 Nov 2018

Study could lead to new diagnostic blood test for Kawasaki disease

For the first time, researchers at University of California San Diego School of Medicine and Imperial College London, with international collaborators, have determined that Kawasaki Disease (KD) can be accurately diagnosed on the basis of the pattern of host gene expression in whole blood. The finding could lead to a diagnostic blood test to distinguish KD from other infectious and inflammatory conditions.

6 Aug 2018