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Study questions efficacy, safety of intranasal ketamine for depression

Nasal spray devices have been touted as a promising way to deliver ketamine to patients with treatment-resistant depression, with this application easier to use and less invasive than other clinical delivery methods such as injections.

16 Mar 2018

The other opioid crisis: Hospital shortages lead to patient pain, medical errors

Even as opioids flood American communities and fuel widespread addiction, hospitals are facing a dangerous shortage of the powerful painkillers needed by patients in acute pain, according to doctors, pharmacists and a coalition of health groups.

16 Mar 2018

Early life stress or trauma could rewire the brain for later neuropathological disorders

Federal researchers have discovered that severe stress or trauma early in life could actually change how the brain responds to stress hormones, essentially "re-wiring" the brain for later neuropathological disorders, according to a study, "A role for corticotrophin releasing factor signaling in the lateral habenula and its modulation by early life stress," published in Science Signaling, March 6.

7 Mar 2018

Ketamine can stop suicidal thoughts finds new study

A study has shown that Ketamine – an anesthetic drug, is capable of reducing and halting suicidal thoughts in depressed patients. The study comes from Columbia University Medical Center (CUMC) who found that it may take only a few hours after administration of ketamine to reduce the suicidal thoughts in the patients.

18 Dec 2017

Study: Ketamine more effective than common sedative in reducing suicidal thoughts

Ketamine was significantly more effective than a commonly used sedative in reducing suicidal thoughts in depressed patients, according to researchers at Columbia University Medical Center.

14 Dec 2017

Common antidepressants may not work for depressed patients with chronic kidney disease

Scientists are finding more evidence that commonly prescribed antidepressants aren't effective in people battling both depression and a chronic medical disease, raising a critical question of whether doctors should enact widespread changes in how they treat millions of depressed Americans.

7 Nov 2017

Opioid-free anesthesia reduces postoperative nausea, study finds

Opioid-free general anesthesia is safe, effective and dramatically decreases postoperative nausea, according to a single-center study of more than 1,000 patients being presented at the ANESTHESIOLOGY 2017 annual meeting.

24 Oct 2017

Research finds decrease in opioid use among patients recovering from hip and knee replacement

Opioid use in patients recovering from hip and knee replacement decreased by one-third between 2006 and 2014, reflecting success in efforts to promote a multimodal approach to pain management (using a variety of methods to manage pain) rather than using opioids alone, reveals new research being presented at the ANESTHESIOLOGY 2017 annual meeting.

23 Oct 2017

Ketamine may hold promise as treatment for migraine headaches unresponsive to other therapies

Ketamine, a medication commonly used for pain relief and increasingly used for depression, may help alleviate migraine pain in patients who have not been helped by other treatments, suggests a study being presented at the ANESTHESIOLOGY 2017 annual meeting.

23 Oct 2017

Tulane researchers move closer to improving treatment for chronic depression

In a new study published in the journal Cell Reports, researchers associated with the Tulane Brain Institute say they have moved a step closer to improving treatment for chronic depression.

7 Sep 2017

New trial shows ketamine's effectiveness to treat geriatric depression

Australian researchers have completed the world's first randomised control trial (RCT) assessing the efficacy and safety of ketamine as a treatment for depression in elderly patients.

24 Jul 2017

Researchers identify key protein that helps trigger ketamine's rapid antidepressant effects

UT Southwestern Medical Center scientists have identified a key protein that helps trigger ketamine's rapid antidepressant effects in the brain, a crucial step to developing alternative treatments to the controversial drug being dispensed in a growing number of clinics across the country.

22 Jun 2017

Study provides evidence for antidepressant effects of ketamine

Better known as an anesthetic or as an illicit hallucinogenic drug, ketamine has also long been noted for alleviating depression. But ketamine has not been tested in a large clinical trial, and all evidence of its antidepressant effects has come from anecdotes and small studies of fewer than 100 patients.

3 May 2017

Ketamine News and Research

Study questions efficacy, safety of intranasal ketamine for depression

The other opioid crisis: Hospital shortages lead to patient pain, medical errors

Early life stress or trauma could rewire the brain for later neuropathological disorders

Ketamine can stop suicidal thoughts finds new study

Study: Ketamine more effective than common sedative in reducing suicidal thoughts

Common antidepressants may not work for depressed patients with chronic kidney disease

Opioid-free anesthesia reduces postoperative nausea, study finds

Research finds decrease in opioid use among patients recovering from hip and knee replacement

Ketamine may hold promise as treatment for migraine headaches unresponsive to other therapies

Tulane researchers move closer to improving treatment for chronic depression

New trial shows ketamine's effectiveness to treat geriatric depression

Researchers identify key protein that helps trigger ketamine's rapid antidepressant effects

Study provides evidence for antidepressant effects of ketamine

Study finds higher state of consciousness under the influence of psychedelic drugs

Intranasal administration of medications becoming more popular in emergency departments

Mount Sinai researchers review progress made in using ketamine and other therapies to treat depression

New study offers insights into how antidepressants work in the brain

Alcohol produces same neural and molecular changes as rapid antidepressant drugs

CHOP researchers exploit gene discovery in severe epilepsy to identify precision treatment

Anaesthetic known for surgical procedures may be quick remedy for depression

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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