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Two papers highlight therapeutic potential of human Sertoli cells

Two papers published in the current issue of Cell Transplantation, now freely available on-line at http://www.ingentaconnect.com/content/cog/ct/, highlight the therapeutic potential of human Sertoli cells that are present in the testes and are also called "nurse" or "mother" cells because they nurture the developing sperm cells.

12 Jul 2011

FDA approves protocol for Medtronic's SYMPLICITY HTN-3 for treatment of hypertension

Medtronic, Inc., announced today that the U.S. Food and Drug Administration (FDA) has conditionally approved the protocol for SYMPLICITY HTN-3, the company's U.S. clinical trial of renal denervation with the Symplicity Catheter System for the treatment of resistant hypertension, an especially dangerous disease affecting hundreds of millions of people worldwide.

From Medtronic 12 Jul 2011

Viewpoints: N.Y. health exchange stalemate; Dick Cheney's heart; vaccine debate refuses to die

Just in case you hadn't noticed, no one has elected Grover Norquist to anything. Still, he looms as a major obstacle to Congress reaching a deficit-reduction agreement needed to raise the federal debt ceiling. … what's revealing about Norquist's passionate advocacy against taxes is that it virtually ignores the main causes of bigger government: Social Security and Medicare.

12 Jul 2011

Cardiology study looks at sodium and potassium in diet

A new study suggests that in addition to cutting the amount of sodium in their diets to improve heart health, Americans should also increase consumption of a key mineral found in many fruits and vegetables, potassium.

11 Jul 2011

Researchers discover how genetic mutations cause rare human diseases

Researchers at the University of California, San Francisco and in Michigan, North Carolina and Spain have discovered how genetic mutations cause a number of rare human diseases, which include Meckel syndrome, Joubert syndrome and several other disorders.

11 Jul 2011

Arizona E. coli related death triggers warning

The Center for Disease Control and Prevention (CDC) and the Arizona Department of Health announced last Friday that a man who recently traveled to Germany was infected by the German E. coli outbreak. The man died from kidney complications. This death was the first U.S. fatality of the relentless epidemic. According to the World Health Organization, 52 have been killed in the outbreak.

10 Jul 2011

Mesenchymal stem cells protect and heal

A stem cell that can morph into a number of different tissues is proving a natural protector, healer and antibiotic maker, researchers at Case Western Reserve University and their peers have found.

8 Jul 2011

Novartis Afinitor Phase III trial on tuberous sclerosis meets primary endpoint

Novartis Pharmaceuticals Corporation announced today Phase III trial results that showed more than one-third of patients taking Afinitor tablets experienced a 50% or greater reduction in the size of their subependymal giant cell astrocytomas, non-cancerous brain tumors associated with tuberous sclerosis complex.

8 Jul 2011

Inhibiting heat shock transcription factor 1 prevents liver cancer in mice

Altering the body's metabolism could be an effective treatment for deadly liver cancer, researchers report.

7 Jul 2011

Sodium intake during pregnancy alters kidney development in offspring

A new animal study from Europe has drawn an association between pregnant mothers' sodium intake and their newborn's kidney development.

7 Jul 2011

ASN President discusses latest information about diabetic nephropathy at ADA

ASN President Dr. Joseph V. Bonventre, MD, PhD, spoke at the American Diabetes Association's annual meeting, 71st Scientific Session, this June in San Diego. Dr. Bonventre was featured at a symposium entitled "New Concepts in Diagnosing and Treating Diabetic Nephropathy."

6 Jul 2011

First flexible endoscopy robotic surgery for gastric tumours performed in India

Patients with gastric tumours in their stomach will no longer have to suffer an eight-hour long surgery, but instead can look forward to a short day surgery which last a few minutes to an hour without the need for hospitalisation.

6 Jul 2011

Infants treated with certain HIV medication more likely to experience adrenal dysfunction

Infants of human immunodeficiency virus 1 (HIV-1) infected mothers who were treated before and after birth with the protease inhibitor lopinavir-ritonavir were more likely to experience adrenal dysfunction, including life-threatening adrenal insufficiency in premature infants, compared with a zidovudine-based regimen, according to a preliminary report in the July 6 issue of JAMA.

6 Jul 2011

Potential new approach for treating obesity, type 2 diabetes

Scientists at the National Institutes of Health have uncovered a pathway in mice that allows white fat - a contributor to obesity and type 2 diabetes - to burn calories in a way that's normally found in brown fat and muscle. The findings are in the July 6 edition of Cell Metabolism.

6 Jul 2011

Periodontal disease can affect woman's chance of conceiving

Professor Roger Hart told the annual meeting of the European Society of Human Reproduction and Embryology that the negative effect of gum disease on conception was of the same order of magnitude as the effect of obesity.

5 Jul 2011

Anti-inflammatory drugs may increase risk of atrial fibrillation

Commonly used painkillers to treat inflammation are linked to an increased risk of irregular heart rhythm, concludes a study published on bmj.com today.

5 Jul 2011

Hidden incision endoscopic technique eliminates visible scarring in kidney surgery

Surgery and all its implications can be scary, especially so for pediatric patients and their parents who dread sometimes disfiguring scars.

2 Jul 2011

Avastin for breast cancer still covered by Medicare despite FDA indecision

The Medicare will continue to cover Avastin for breast cancer treatment even if U.S. Food and Drug Administration Commissioner Peggy Hamburg decides to withdraw Avastin for such use, according to Don McLeod, a spokesman for the Centers for Medicare and Medicaid. McLeod said, in his statement, “The FDA decision, when it comes, does not affect CMS.”

1 Jul 2011

Panel advises FDA to reject Avastin as breast cancer drug

The unanimous recommendation by this committee of cancer experts increases the likelihood that the drug will no longer be widely available for the treatment of breast cancer. Avastin, however, will continue to have the Food and Drug Adminstration's approval for use in treating certain other cancers.

1 Jul 2011

Diagnostic delay in women with tuberous sclerosis complex increases mortality risk

Women with tuberous sclerosis complex (TSC) are often misdiagnosed because the condition, commonly recognized in early childhood when it presents with seizures, manifests differently later in life, typically with renal angiomyolipomas - a benign tumor of the kidney - and pulmonary lymphangioleiomyomatosis (LAM) - a rare lung disease that affects almost exclusively women.

30 Jun 2011