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Functional tests are necessary to understand human disease despite genetic sequencing

Despite what you might have heard, genetic sequencing alone is not enough to understand human disease. Researchers at Duke University Medical Center have shown that functional tests are absolutely necessary to understand the biological relevance of the results of sequencing studies as they relate to disease, using a suite of diseases known as the ciliopathies which can cause patients to have many different traits.

24 Jan 2011

What protects certain diabetics from complications?

Much research has been carried out on why diabetics develop complications. Now researchers are asking the question the other way around. They want to know why some diabetic patients do not develop complications. What is it that protects them? The PROLONG study could provide the answer.

21 Jan 2011

Vasopressin in the brain maintains size of vasopressin neurons even when body fluid becomes more diluted

The anti-diuretic hormone "vasopressin" is released from the brain, and known to work in the kidney, suppressing the diuresis.

21 Jan 2011

MGH Bipolar CHOICE trial to evaluate effectiveness of new medications compared to lithium

The Massachusetts General Hospital (MGH) Bipolar Clinic and Research Program with the Bipolar Trials Network is launching Bipolar CHOICE, a 10-site nationwide trial evaluating the real-world advantages and disadvantages of quetiapine, a widely prescribed second generation antipsychotic mood stabilizing medication, compared to lithium, the gold standard mood stabilizer, for the treatment of outpatients with bipolar disorder.

21 Jan 2011

INF2 gene mutation is a major cause for focal segmental glomerulosclerosis

Mutations in a gene called INF2 are by far the most common cause of a dominantly inherited condition that leads to kidney failure, according to a study appearing in an upcoming issue of the Journal of the American Society Nephrology. The results may help with screening, prevention, and therapy.

21 Jan 2011

Routine mammograms can show arterial calcium deposits in women with ESRD, CKD

Routine mammograms performed for breast cancer screening could serve another purpose as well: detecting calcifications in the blood vessels of patients with advanced kidney disease, according to a study appearing in an upcoming issue of the Clinical Journal of the American Society of Nephrology.

21 Jan 2011

ACT Biotech releases telatinib Phase 2 trial data for metastatic stomach cancer

ACT Biotech, a biopharmaceutical company focused on the development of highly targeted, oral therapeutics for the treatment of cancer, today released data on additional analysis of the Phase 2 clinical trial of telatinib in patients with metastatic stomach cancer that further supports the highly-potent nature of the antiangiogenic agent.

21 Jan 2011

Successful larynx transplant for Californian woman

In a breakthrough, a surgical team in California on Thursday announced that they had successfully replaced the larynx of a 52-year-old woman who hadn’t been able to speak or breathe on her own for more than a decade.

20 Jan 2011

Researchers identify PBRM1 gene mutation in one in three patients with common form of renal cancer

In a collaborative project involving scientists from three continents, researchers have identified a gene that is mutated in one in three patients with the most common form of renal cancer.

20 Jan 2011

Eating more fruits and vegetables may reduce risk of heart disease: New Study

New research indicates that eating more fruits and vegetables may reduce your risk of dying from heart disease. According to a new study from the University of Oxford and published in the European Heart Journal, people who consumed eight or more servings of fruits and vegetables each day were 22 percent less likely to die from ischemic heart disease than those who consumed three or fewer servings a day.

20 Jan 2011

Legionnaires’ disease scare in Bali: Australian tourists warned

Commonwealth chief medical officer Jim Bishop has warned Australians who have returned from Bali on an outbreak of Legionnaires’ disease on the popular Indonesian resort island. The Australian health authorities knew of 11 cases of Legionnaires’ disease detected in Victorians and Western Australians after holidays in the Kuta area of Bali between August 2010 and January 2011.

19 Jan 2011

Home blood pressure monitors can help people keep blood pressure in check

A recent research review has concluded that home blood pressure monitors can help people keep their blood pressure in check and possibly cut down on medication – as long as patients and their doctors put those home readings to good use. For years, Omron Healthcare, Inc. has reminded Americans how important home blood pressure monitoring is when it comes to reducing their risk of a heart attack or stroke, and truly wants people to take the news to heart in 2011.

19 Jan 2011

Kidney transplant surgeon receives Loyola's Spirit of Martin Luther King Jr. Award

Each year, Loyola University Health System presents its prestigious Spirit of Martin Luther King Jr. Award to an employee who provides inspirational service to others in the spirit of the slain civil rights leader.

19 Jan 2011

Common genetic risk factor for heart failure in Caucasians also linked to kidney function

Nearly five million Americans live with heart failure, with as many as 700,000 new cases diagnosed each year. In addition to lifestyle factors, scientists have shown that heart failure has a strong heritable component, but identifying the responsible genes has been a major challenge. Now, new research has identified a common genetic risk factor for heart failure in Caucasians that is also linked to kidney function.

19 Jan 2011

Uric acid levels linked to severe osteoarthritis

The amount of uric acid in one's joints may increase the likelihood of severe osteoarthritis, the most common form of arthritis worldwide, according to researchers at Duke University Medical Center.

19 Jan 2011

New study reveals measles viral gene plays key role in development of PD

A gene from the measles virus plays a key role in the development of Paget's disease of bone, according to a team of researchers led by the University of Pittsburgh School of Medicine.

18 Jan 2011

Researchers find kidney-specific gene defects may increase risk of heart failure

Scientists have identified the first DNA sequence variant common in the population that is not only associated with an increased risk of heart failure, but appears to play a role in causing it.

18 Jan 2011

Research provides evidence of blood pressure control system in distal nephron of kidney

Today scientists at The University of Texas Health Science Center San Antonio reported how this essential function of the distal nephron is regulated. They demonstrated that sodium handling by the distal nephron is under the control of a local regulatory system.

18 Jan 2011

Painkillers and heart attack risk

A new study has shown that taking certain commonly used painkillers for long periods or in high doses increases the risk of heart attacks or strokes. The study comes from researchers from Bern University and is published in the British Medical Journal.

16 Jan 2011

Home dialysis as effective as hospital dialysis for patients with kidney transplant failure

Patients who must return to dialysis after a kidney transplant failure survive just as well on home dialysis as hospital dialysis, but few choose that option, according to new research by Dr. Jeffrey Perl, a nephrologist at St. Michael's Hospital.

14 Jan 2011

Kidney News and Research

Functional tests are necessary to understand human disease despite genetic sequencing

What protects certain diabetics from complications?

Vasopressin in the brain maintains size of vasopressin neurons even when body fluid becomes more diluted

MGH Bipolar CHOICE trial to evaluate effectiveness of new medications compared to lithium

INF2 gene mutation is a major cause for focal segmental glomerulosclerosis

Routine mammograms can show arterial calcium deposits in women with ESRD, CKD

ACT Biotech releases telatinib Phase 2 trial data for metastatic stomach cancer

Successful larynx transplant for Californian woman

Researchers identify PBRM1 gene mutation in one in three patients with common form of renal cancer

Eating more fruits and vegetables may reduce risk of heart disease: New Study

Legionnaires’ disease scare in Bali: Australian tourists warned

Home blood pressure monitors can help people keep blood pressure in check

Kidney transplant surgeon receives Loyola's Spirit of Martin Luther King Jr. Award

Common genetic risk factor for heart failure in Caucasians also linked to kidney function

Uric acid levels linked to severe osteoarthritis

New study reveals measles viral gene plays key role in development of PD

Researchers find kidney-specific gene defects may increase risk of heart failure

Research provides evidence of blood pressure control system in distal nephron of kidney

Painkillers and heart attack risk

Home dialysis as effective as hospital dialysis for patients with kidney transplant failure

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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