Kidney News and Research

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Compounds that trigger beta cell replication identified

Researchers at the Genomics Institute of the Novartis Research Foundation (GNF) have identified a set of compounds that can trigger the proliferation of insulin-producing cells in the pancreas, using sophisticated high-throughput screening techniques.

25 Feb 2009

New cancer treatment stops aggressive sarcomas

After all standard treatments had failed, a new cancer treatment has stopped the growth of aggressive sarcomas in two recent patients. These results are similar to the new protocol's previous success against several cancers, including melanoma, pancreatic, colon, mesothelioma and other sarcomas.

25 Feb 2009

Updated formula measures kidney function more accurately

Measuring kidney function in children can be expensive, time-consuming for clinicians, and tedious for children, who may be exposed to radioactivity and subjected to a large number of blood draws.

24 Feb 2009

Children with hypertension have trouble with goal-directed tasks

Children with high blood pressure are not as good at complicated, goal-directed tasks, have more working memory problems and are not as adept at planning as their peers without hypertension, according to recent research.

24 Feb 2009

Updated formula measures kidney function more accurately

Measuring kidney function in children can be expensive, time-consuming for clinicians, and tedious for children, who may be exposed to radioactivity and subjected to a large number of blood draws.

24 Feb 2009

Tiny flakes of silicon spotlight tumors, deliver drugs

Small is promising when it comes to illuminating tiny tumors or precisely delivering drugs, but many worry about the safety of nano-scale materials.

22 Feb 2009

High-flux hemodialysis prolongs survival in chronic kidney disease

High-flux hemodialysis (which removes large toxins) reduces the risk of premature death in many patients with chronic kidney disease (CKD), according to a study appearing in the March 2009 issue of the Journal of the American Society Nephrology (JASN).

22 Feb 2009

Toenail clippings reveal environmental arsenic exposure

Scientists from Leicester and Nottingham have devised a method for identifying levels of exposure to environmental arsenic - by testing toenail clippings.

22 Feb 2009

Kidney disease affects response to anticoagulant drug warfarin

Patients with reduced kidney function require lower doses of the anticoagulant drug warfarin, and may need closer monitoring to avoid serious bleeding complications, suggests a study in the April 2009 issue of the Journal of the American Society of Nephrology ( JASN ).

20 Feb 2009

GlaxoSmithKline starts phase III trial of Syncria (albiglutide) type 2 diabetes medication

GlaxoSmithKline has announced initiation and dosing of the first patient of the Phase III clinical trial programme to evaluate the efficacy, safety and tolerability of the investigational GLP-1 (Glucagon-like peptide 1) agonist Syncria (albiglutide) in men and women with type 2 diabetes.

18 Feb 2009

Hormone aldosterone linked to high blood pressure and blood vessel disease in African Americans

Researchers at The Medical College of Wisconsin in Milwaukee have linked higher levels of the hormone aldosterone to high blood pressure and blood vessel disease in African Americans.

17 Feb 2009

Senior patients benefit from selective use of early revascularization

The elderly represent a growing proportion of patients presenting with acute myocardial infarction (MI) complicated by cardiogenic shock (CS).

16 Feb 2009

Leptin shows potential for type 1 diabetes

Terminally ill rodents with type 1 diabetes have been restored to full health with a single injection of a substance other than insulin by UT Southwestern Medical Center scientists.

16 Feb 2009

New trial targets kidney cancer drug sorafenib in bladder cancer

According to the American Cancer Society, 69,000 cases of bladder cancer were diagnosed nationwide last year with some 2,600 new cases in New Jersey.

16 Feb 2009

Higher blood sugar levels linked to lower brain function in diabetics

Results of a recent study conducted by researchers at Wake Forest University Baptist Medical Center and colleagues show that cognitive functioning abilities drop as average blood sugar levels rise in people with type 2 diabetes.

16 Feb 2009

Common gene variants increase risk of hypertension, may lead to new therapies

A new study has identified the first common gene variants associated with an increased incidence of hypertension - a significant risk factor for heart attack, stroke and kidney failure.

16 Feb 2009

Avosentan shows prmoise for diabetic kidney disease

A new drug called avosentan significantly lowers urinary protein excretion-an important marker of kidney disease progression-in patients with diabetic kidney disease, according to an international clinical trial appearing in the March 2009 issue of the Journal of the American Society Nephrology (JASN).

16 Feb 2009

New test for mysterious metabolic diseases

Scientists at Stanford University School of Medicine have devised a much-needed way to monitor and find treatments for a mysterious and devastating group of metabolic diseases that arise from mutations in cells' fuel-burning mechanism.

15 Feb 2009

Candesartan cilexetil reduces proteinuria in kidney disease patients

Taking a much higher than recommended dose of the hypertension drug candesartan cilexetil effectively lowered the amount of protein excreted in the urine of patients with kidney disease, according to a study appearing in the April 2009 issue of the Journal of the American Society Nephrology ( JASN ).

11 Feb 2009

Healthy people with high urinary protein levels have elevated kidney disease risk

Measuring the amount of protein lost in the urine can identify individuals at risk of developing kidney disease, according to a study appearing in the April 2009 issue of the Journal of the American Society Nephrology (JASN).

11 Feb 2009