Kidney Failure News and Research

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People with end-stage renal disease and psoriasis do not have increased risk for heart attack

Studies have suggested that psoriasis is an independent risk factor for heart attack in the general population, but investigators have made the surprising finding that in people who also have end-stage renal disease, which shares many risk factors with heart disease, it is not.

18 Oct 2022

Scientists show how cellular hypoxia response increases fetal hemoglobin expression in adults

Scientists at St. Jude Children's Research Hospital have shown how a protein responsible for adapting to low oxygen conditions (hypoxia), causes increased expression of fetal hemoglobin (HbF) in adults.

12 Oct 2022

DOAC use associated with lower risk of kidney complications in patients with atrial fibrillation

Swedish cohort study shows 13% (95% CI, 2-22%) lower risk of kidney function decline or kidney failure and 12% (95% CI, 3-20%) lower risk of acute kidney injury with use of direct oral anticoagulants vs. vitamin K antagonists for non-valvular atrial fibrillation.

5 Oct 2022

Mortality prediction model for dementia patients may help guide decisions on end-of-life care

A mortality prediction model for older adults with dementia may help clinicians frame discussions with patients and their families relating to end-of-life care, such as at-home support and nursing homes.

26 Sep 2022

Systemic inflammation triggered by SARS-CoV-2 found to cause human testicular injury

In a new study, a team of researchers demonstrated that testicular injury in humans is not due to direct SARS-CoV-2 infection but more likely is an indirect effect of exposure to systemic inflammation or SARS-CoV-2 antigens.

26 Sep 2022

Study identifies genetic variation linked with posterior urethral valves in males

Genetic variation affecting developmental genes not previously linked to urethral development may contribute to a congenital condition that is the most common cause of kidney failure in young males, a study published today in eLife suggests.

20 Sep 2022

Study identifies a promising target for polycystic kidney disease treatment

Blocking the inhibition of PKD1 and PKD2 gene expression by deleting a binding site for microRNAs hindered the formation and growth of kidney cysts in autosomal dominant polycystic kidney disease (ADPKD) models, UT Southwestern researchers reported.

16 Sep 2022

Scientists unravel the molecular origin of rare genetic disease cystinosis

The rare genetic disease cystinosis is caused by mutations in the gene for a protein called cystinosin. A team of scientists has now solved the structure of cystinosin and determined how mutations interfere with its normal function, providing insights into the underlying mechanisms and suggesting a way to develop new treatments for the disease.

15 Sep 2022

Study reveals recommended levels of long-term blood sugar to avoid diabetes-related damage

The levels of long-term blood sugar, HbA1c, can be used to accurately determine the risk of a person with type 1 diabetes developing eye- and kidney complications.

12 Sep 2022

Organ transplants are up, but the agency in charge is under fire

For the past decade, Precious McCowan's life has revolved around organ transplants. She's a doctoral candidate studying human behavior in Dallas who has survived two kidney transplants. And in the midst of her end-stage renal disease, her 2-year-old son died. She chose to donate his organs in hopes they would save a life.

7 Sep 2022

CDC provides latest updates on the number of individuals infected with E. coli O157 outbreak strain

A CDC investigation notice update regarding a multistate outbreak of E. coli O157 infections is now live: https://www.cdc.gov/ecoli/2022/o157h7-08-22/index.html

2 Sep 2022

People of African-Caribbean heritage living with diabetes have greater kidney disease risk

New research confirms for the first time that ethnicity is a risk factor for developing kidney disease in people with Type 1 diabetes.

1 Sep 2022

Research provides a major step forward to growing human kidney in a dish

Kidney disease affects one in nine adults globally and the incidence of kidney failure is steadily rising around the world.

30 Aug 2022

Tight control of blood sugar in teens may help reduce diabetes-related brain damage

Tight control of blood sugar in teens with Type 1 diabetes may help reduce the disease's damaging effects on the brain, effects which have been shown even in younger children, according to a study published online today in Nature Communications.

30 Aug 2022

New update on CDC's investigation of multistate outbreak of E. coli O157 infection

A CDC investigation notice update regarding a multistate outbreak of E. coli O157 infections is now live: https://www.cdc.gov/ecoli/2022/o157h7-08-22/index.html

26 Aug 2022

Youth-onset type 2 diabetes climbed 77% amid COVID-19, study shows

Data suggests diagnoses of type 2 diabetes in children are increasing 4-5% per year. Type 2 diabetes occurs when the cells in the body do not respond to insulin, which increases the body's need for insulin.

24 Aug 2022

Report: Australians receiving kidney replacement therapy more than doubled between 2000 and 2020

The number of Australians receiving kidney replacement therapy more than doubled between 2000 and 2020, from 11,700 to 27,700.

23 Aug 2022

Intake of lysine prevents hypertensive kidney disease in animal models

Can you eat your way out of a kidney disease? Perhaps you can – according to a new study from Aarhus University.

19 Aug 2022

Hackensack Meridian Health becomes second in the world to implant Impella Bridge-to-Recovery heart pump

Hackensack Meridian Health, Hackensack University Medical Center cardiac surgeon Yuriy Dudiy, M.D. became the second in the world to successfully implant the Impella Bridge-to-Recovery (BTR)™ heart pump for the technology's U.S. Food and Drug Administration (FDA) early feasibility study (EFS) investigational device exemption (IDE).

17 Aug 2022

Aldosterone may increase risk of kidney failure in patients with chronic kidney disease

A steroid hormone called aldosterone is linked to an increased risk of kidney failure in patients with chronic kidney disease (CKD), according to a study published in the European Heart Journal today (Tuesday).

8 Aug 2022