Kidney Transplant News and Research

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A kidney transplant is an operation where a healthy kidney from one person (the donor) is transferred to a person who has little or no kidney function (the recipient).

Experimental immunusuppressant drug preserves transplanted kidneys

An international team of transplant physicians has shown that the investigational drug belatacept (LEA29Y) preserves transplanted kidney function as effectively as cyclosporine, the drug most commonly used to prevent the immune system from rejecting transplanted organs.

24 Aug 2005

New drug that selectively blocks immune responses protects kidneys after transplant

In an international clinical trial, a new drug that selectively blocks immune responses has proved as effective in preventing acute kidney transplant rejection as cyclosporine, the standard anti-rejection treatment.

24 Aug 2005

Daclizumab effective at reducing organ rejection and risk of infection in heart transplant patients

A new study shows that a drug, called daclizumab, is effective at reducing organ rejection and risk of infection in heart transplant patients. The multi-center study by cardiologists from the United States, Sweden, Germany and Canada will be published in the June 30 issue of The New England Journal of Medicine.

30 Jun 2005

Viagra's non-blood pressure effect successfully mimics vasopressin action

Normally your kidneys filter about 50 gallons of blood a day, remove such waste as salts and minerals, and concentrate it into urine. When you exercise or don't take in water, your blood "thickens" and instead of removing water, the kidney reverses the process, pulls in water from the body that would normally go into the urine, and puts it into the blood, thus maintaining water balance.

29 Jun 2005

Indigenous health gap wider in New Zealand

The health gap between Maori and European New Zealanders is wider than that between American Indians and the US majority white population in the United States, a researcher from The University of Auckland has found.

16 Jun 2005

Three pancreatic islet cell transplants successfully treat type 1 diabetic woman

A Davidson woman has been successfully treated for her Type 1 diabetes through a procedure performed at Carolinas Medical Center. Paul F. Gores, M.D., has led a multi-disciplinary team through a series of three pancreatic islet cell transplants since the summer of 2003. The result is a patient who is now insulin-free.

8 Jun 2005

Six deaths in transplant patients now linked to rodent virus

In the latest news on the subject, experts now believe they can link at least six deaths of organ transplant patients to a rodent virus, which raises questions about whether others may have gone undetected and whether the germ also could spread through blood transfusions.

24 May 2005

Virus from rodents kills three transplant recipients

Three transplant patients have died as a result of receiving an organ from a donor who had unknowingly been infected with a common rodent virus. A fourth patient who received a kidney from the organ donor is recovering.

24 May 2005

Scientists dramatically slow organ transplant rejection

That's the promising implication of an animal study carried out by researchers at the University of Alabama at Birmingham (UAB) and the University of Florida (UF) published in today's (May 2) issue of Proceedings of the National Academy of Sciences.

3 May 2005

Number and quality of kidney transplants much greater if national matching program adopted

A collaboration between Johns Hopkins and Massachusetts Institute of Technology scientists has mathematically demonstrated that a national matching program for kidney paired donation, also called paired kidney exchange, would ensure the best possible kidney for the greatest number of recipients who have incompatible donors.

19 Apr 2005

Kidney transplant can reverse systolic heart failure

Doctors at the University of Maryland Medical Center say that contrary to conventional thinking, a kidney transplant can significantly improve the heart function of people on dialysis with a serious form of heart failure.

6 Apr 2005

Blood pressure control suggests new approach to hypertension therapy

The kidneys have long been known to play a major role in many cases of high blood pressure, but a new study by researchers at Duke University Medical Center reveals that the body's control of blood pressure depends as much on other organs in the body.

3 Apr 2005

You can no longer make the argument that transplanting a kidney into an older recipient is a wasted organ

Growing evidence suggests that age alone shouldn't prevent older adults from being organ donors – or having a kidney transplant themselves – according to researchers at Wake Forest University Baptist Medical Center.

14 Mar 2005

Suitcase-sized machine helps patients undergoing rigorous dialysis for kidney failure

A suitcase-sized machine tested at the Indiana University School of Medicine is making life easier for some patients undergoing rigorous dialysis for kidney failure.

7 Mar 2005

Mutations in newly discovered gene, NPHP5 cause Senior-Loken syndrome

Scientists at the University of Michigan Medical School have discovered a gene called NPHP5 and found mutations in this gene that cause a rare genetic disease called Senior-Loken syndrome. Children with this syndrome develop a type of cystic kidney disease called nephronophthisis, as well as a form of blindness called retinitis pigmentosa.

3 Mar 2005

Up to 500,000 Americans will develop lupus-related kidney disease

According to the Lupus Foundation of America, an estimated 300,000 to 500,000 Americans with the autoimmune disease lupus eventually will develop lupus-related kidney disease, known as lupus nephritis. Lupus nephritis is one of the most serious manifestations of lupus and can lead to serious health problems, kidney failure, disability or death.

27 Feb 2005

NIH awards grant to explore causal relationship between epoetin dose and survival of hemodialysis patients

The National Institutes of Health, National Institute of Diabetes & Digestive & Kidney Diseases (NIDDK) has awarded a two-year grant to the Medical Technology and Practice Patterns Institute (MTPPI) in collaboration with Harvard School of Public Health (HSPH) to explore the causal relationship between epoetin dose and survival of hemodialysis patients receiving this therapy.

27 Feb 2005

Risks of obesity in children with kidney transplants

Obese children who get kidney transplants tend to be younger, shorter and on dialysis longer than their leaner peers, according to a study in the February issue of the journal Pediatrics.

7 Feb 2005

10 to 20 million people in the United States have chronic kidney disease but most don’t know it

10 to 20 million people in the United States have chronic kidney disease but most don’t know it, according to a study by researchers at the Johns Hopkins Bloomberg School of Public Health, the National Institute of Diabetes and Digestive and Kidney Diseases and the National Center for Health Statistics.

19 Dec 2004

Generic antipsychotic drugs can protect brain cells from progressive multifocal leukoencephalopathy

Generic antipsychotic drugs can protect brain cells from a virus that causes a fatal nervous system disorder, according to research conducted at Brown University and Case Western Reserve University.

18 Nov 2004