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Tykerb (lapatinib) - new anti-cancer treatment approved

The Food and Drug Administration (FDA) has approved Tykerb (lapatinib), a new targeted anti-cancer treatment, to be used in combination with capectabine (Xeloda), another cancer drug, for patients with advanced, metastatic breast cancer that is HER2 positive (tumors that exhibit HER2 protein).

14 Mar 2007

Disorderly protein brings order to cell division

The secret to the ability of a molecule critical for cell division to throw off the protein yoke that restrains its activity is the yoke itself - a disorderly molecule that seems to have a mind of its own, say investigators at St. Jude

13 Mar 2007

New insight into brain disorders

The function of an enzyme in the brain - strongly linked to a number of major brain diseases such as Alzheimer's, schizophrenia and bi-polar disorder - has been identified for the first time by researchers at the University of Bristol.

1 Mar 2007

Fox Chase Cancer Center and Cancer Research Technology initiate drug discovery collaboration

Cancer Research Technology Inc. (CRT Inc.) and Fox Chase Cancer Center have announce the initiation of an oncology-focused drug discovery collaboration.

1 Mar 2007

Researchers wake up viruses inside tumors to image and then destroy cancers

They say this strategy could offer a novel way of treating many cancers associated with Epstein-Barr, including at least four different types of lymphoma and nasopharyngeal and gastric cancers.

1 Mar 2007

Power-boosting signal in muscle declines with age

As people age, they may have to exercise even harder to get the benefits afforded to younger folk. That's the suggestion of a report in the February issue of the journal Cell Metabolism, showing that a signal that gives muscles a kind of metabolic boost in response to exercise is blunted in older animals.

6 Feb 2007

SH2B1 protein plays a key role in controlling body weight, response to insulin and leptin

A single protein in brain cells may act as a linchpin in the body's weight-regulating system, playing a key role in the flurry of signals that govern fat storage, sugar use, energy balance and weight, University of Michigan Medical School researchers report.

29 Jan 2007

Disorderly protein brings order to cell division

The secret to the ability of a molecule critical for cell division to throw off the protein yoke that restrains its activity is the yoke itself a disorderly molecule that seems to have a mind of its own, say investigators at St. Jude Children's Research Hospital, Innsbruck Medical University and Max Planck Institute.

28 Jan 2007

Experimental drug provides powerful therapy against acute myeloid leukemia

Researchers at The University of Texas M. D. Anderson Cancer Center have found, in laboratory studies, that the experimental drug ABT-737 which has shown promise in some cancers, can destroy acute myeloid leukemia (AML) blast, progenitor and even stem cells that are often resistant to standard chemotherapy treatment.

19 Nov 2006

Cancer Research Technology to present discovery updates at BioEurope 2006

Cancer Research Technology Limited (CRT), the oncology-focused development and commercialisation company, today announce that Phil L'Huillier, the Director of Business Management, will present at the BioEurope 2006 Annual International Partnering Conference.

6 Nov 2006

Scientists step toward next generation of cancer-beating drugs

Scientists helping to develop the next generation of cancer-beating drugs say they have had a major breakthrough with their latest results.

From The University of Manchester 26 Oct 2006

Cocktail of two drugs heals damaged hearts

A cocktail of drugs has been found in trials with animals to heal damaged heart muscle.

10 Oct 2006

Researchers create roadmap to integrin activation

Calling it an important technical advance in the study of the complex receptors and pathways of the body's cellular system, researchers at the University of California, San Diego (UCSD) School of Medicine have reconstructed the signaling pathways that impact activation of a receptor that is critical to the control of bleeding and to the thrombosis that occurs in heart attacks and strokes.

18 Sep 2006