Knee Replacement News and Research

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Semuloparin reduces incidence of VTE in orthopedic surgery patients, study finds

An ultra-low-molecular-weight heparin called semuloparin has been found to reduce the incidence of venous thromboembolism in orthopedic surgery patients in a large clinical program being lead by a steering committee chaired by McMaster University professor Dr. Alexander Turpie.

9 Jul 2010

Phase II trial results of TB-402 presented at International Congress on Thrombosis

BioInvent International AB and ThromboGenics NV announce that the positive results from a Phase II trial of TB-402 (Anti-Factor VIII antibody) were presented at the 21st International Congress on Thrombosis in Milan, Italy yesterday. TB-402 is a novel, long acting anticoagulant that is being developed as a single injection for the prevention of venous thromboembolism following orthopaedic surgery.

9 Jul 2010

Medical school association suggests clinical conflict-of-interest policies

The Association of American Medical Colleges has asked academic medical institutions to adopt conflict-of-interest policies for clinical care similar to those they apply to medical research, Modern Healthcare reports.

2 Jul 2010

New oral blood-thinning drugs may have dangerous interactions when taken with prescription drugs : Study

Three new oral blood-thinning drugs nearing approval by the Food and Drug Administration are more convenient than the standard drug Coumadin® because they do not require monthly visits to adjust doses.

2 Jun 2010

Exactech acquires Brighton Partners

Exactech, Inc., a developer and producer of bone and joint restoration products for hip, knee, shoulder, spine and biologic materials, announced today that the company has acquired Brighton Partners, Inc., the sole source supplier of the direct compression molded polyethylene bearings used exclusively in Exactech's flagship product, the Optetrak® knee replacement system.

25 May 2010

Phase II trial: TB-402 demonstrates superior antithrombotic activity to enoxaparin

BioInvent International AB and ThromboGenics NV announce today positive results from their Phase II trial of TB-402. TB-402 is a novel, long acting anticoagulant that is being developed as a single injection for the prevention of venous thromboembolism following orthopaedic surgery.

6 May 2010

ThromboGenics, BioInvent International report positive results from Phase II trial of TB-402 for VTE

ThromboGenics NV and co-development partner BioInvent International announce today positive results from their Phase II trial of TB-402. TB-402 is a novel, long acting anticoagulant that is being developed as a single injection for the prevention of venous thromboembolism (VTE) following orthopaedic surgery.

6 May 2010

Additional pivotal Phase 3 trial data for MoxDuo IR released

QRxPharma announced today the release of additional pivotal Phase 3 trial data for MoxDuo IR, an immediate-release Dual-Opioid pain therapy. Required for New Drug Application submission with the United States Food and Drug Administration, this "combination rule" study compared the efficacy and safety profiles of MoxDuo IR against component doses of morphine and oxycodone alone for the management of moderate to severe post-operative pain following bunionectomy surgery.

5 May 2010

Surgeons can now customize artificial knee implants, prevent future revision surgeries

Throughout the years orthopedic surgeons have learned that one size does not fit all when it comes to joint replacements. Because of advancements in technology, surgeons can now customize artificial knee implants and prevent future revision surgeries.

4 May 2010

Bristol-Myers Squibb reports 11% increase in first-quarter 2010 revenue

Bristol-Myers Squibb Company today reported strong sales and earnings growth for the first quarter of 2010.

30 Apr 2010

$Ageing population prone to bone fractures drives South African joint replacement market$

Ageing population prone to bone fractures drives South African joint replacement market

The joint replacement market in South Africa is set to experience continued growth in the medium to long term, driven by an ageing population that is prone to cartilage degeneration and bone fractures. The introduction of innovative products with enhanced durability and longevity as well as safer operation techniques is further boosting growth in this market.

29 Apr 2010

ConforMIS' iUni G2 patient-specific knee replacement system receives CE Mark certification

ConforMIS, Inc. announced today that the iUni® G2 has received CE Mark certification, providing regulatory approval for ConforMIS to begin the sale of this products throughout the European Union. The iUni G2 is the next generation of ConforMIS' revolutionary patient-specific knee replacement system, and remains the only patient-specific unicompartmental knee resurfacing implant on the market.

15 Apr 2010

Computer-Assisted Robotic Total Knee Replacements better than conventional techniques

A study of 1,000 consecutive Computer-Assisted Robotic Total Knee Replacements performed over a five year period at Mercy Medical Center in Rockville Centre, NY demonstrates that the computer-assisted procedures result in far better leg alignment, much less likelihood of complicating infection, and a far lower early failure rate than surgeries performed using conventional techniques.

12 Apr 2010

Five-year, $3.7M trial evaluates customized warfarin dosage based on patient genetics

A five-year, $3.7 million clinical trial will investigate how to balance the benefits and risks of warfarin, a drug that helps prevent potentially deadly blood clots.

9 Apr 2010

Mobile compression device effective in preventing blood clots after hip replacement surgery

A mobile compression device is as effective as medication at preventing the formation of blood clots after hip replacement surgery but provides greater patient safety, according to a study in the March issue of the Journal of Bone & Joint Surgery.

7 Apr 2010

Study: Hormone replacement in joint fluid might be beneficial in treating osteoarthritis

German researchers determined that concentrations of the sex hormones, testosterone in men and estrogen in women, may have a positive effect on the regenerative potential of cartilage tissue. The study suggests hormone replacement in the joint fluid of men and women might be beneficial in treating late stages of human osteoarthritis by regenerating damaged tissue.

30 Mar 2010

Total knee replacement surgery more common among younger patients

A research team led by Mayo Clinic has found a national trend toward younger, more diverse patients having total knee replacement surgery.

15 Mar 2010

Study finds implant durability not affected by high-impact sports participation

Total knee arthroplasty (TKA) patients may be able to participate in high-impact sports without increasing risk of early implant failure, according to a new study presented today at the 2010 Annual Meeting of the American Academy of Orthopaedic Surgeons (AAOS).

15 Mar 2010

TKR relieves pain and improves balance in elderly patients with advanced knee arthritis

Total knee replacement successfully relieves pain and improves function in patients with advanced knee arthritis, according to a study presented today at the 2010 Annual Meeting of the American Academy of Orthopaedic Surgeons (AAOS). The surgery also significantly improves dynamic balance among elderly patients.

12 Mar 2010

Survey: Employers plan to shift more health costs to workers

The Washington Post: "Most big employers plan to shift a larger share of health-care costs to their workers next year, according to a survey to be released Thursday. ... Meanwhile, employees at many companies can expect significantly higher premiums, deductibles and co-payments, according to the annual survey by the National Business Group on Health, a coalition of big employers, and Towers Watson, a consulting firm that advises companies on employee benefits."

12 Mar 2010

Knee Replacement News and Research

Semuloparin reduces incidence of VTE in orthopedic surgery patients, study finds

Phase II trial results of TB-402 presented at International Congress on Thrombosis

Medical school association suggests clinical conflict-of-interest policies

New oral blood-thinning drugs may have dangerous interactions when taken with prescription drugs : Study

Exactech acquires Brighton Partners

Phase II trial: TB-402 demonstrates superior antithrombotic activity to enoxaparin

ThromboGenics, BioInvent International report positive results from Phase II trial of TB-402 for VTE

Additional pivotal Phase 3 trial data for MoxDuo IR released

Surgeons can now customize artificial knee implants, prevent future revision surgeries

Bristol-Myers Squibb reports 11% increase in first-quarter 2010 revenue

Ageing population prone to bone fractures drives South African joint replacement market

ConforMIS' iUni G2 patient-specific knee replacement system receives CE Mark certification

Computer-Assisted Robotic Total Knee Replacements better than conventional techniques

Five-year, $3.7M trial evaluates customized warfarin dosage based on patient genetics

Mobile compression device effective in preventing blood clots after hip replacement surgery

Study: Hormone replacement in joint fluid might be beneficial in treating osteoarthritis

Total knee replacement surgery more common among younger patients

Study finds implant durability not affected by high-impact sports participation

TKR relieves pain and improves balance in elderly patients with advanced knee arthritis

Survey: Employers plan to shift more health costs to workers

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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