Lab on a Chip News and Research

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Advances in the field of nanotechnology have led to the development of miniaturized devices called lab-on-a-chip (LOC). Lithography, in particular, has helped create nanoscale impressions on the surface of metals and semiconductors.

Researchers develop new technique for pH adjustments

How do individual cells or proteins react to changing pH levels? Researchers at the MESA+ Institute for Nanotechnology at the University of Twente have developed a technique for 'gently' adjusting pH: in other words, without damaging biomolecules. This should soon allow them to measure the activity of a single enzyme as a function of pH.

22 Dec 2009

IBM scientists create one-step point-of-care-diagnostic test based on innovative silicon chip

IBM (IBM) scientists have created a one-step point-of-care-diagnostic test, based on an innovative silicon chip, that requires less sample volume, is significantly faster, portable, easy to use, and can test for many diseases, including one of world's leading causes of death, cardiovascular disease.

18 Nov 2009

Rice University's new BRC awarded $2M NIH grant to develop an inexpensive test for oral cancer

The National Institutes of Health (NIH) has awarded researchers in Rice University's new BioScience Research Collaborative (BRC) a $2 million Grand Opportunity (GO) grant to develop a fast, inexpensive test for oral cancer that a dentist could perform simply by using a brush to collect a small sample of cells from a patient's mouth.

6 Nov 2009

Micro-injector may help rapid development of new generation of drugs

It's no bigger than a stamp packet but it has the potential to allow rapid development of a new generation of drugs and genetic engineering organisms, and to better control in-vitro fertilization.

5 Nov 2009

Researchers develop a new test process for cancer drugs

It is very difficult to predict whether a cancer drug will help an individual patient: only around one third of drugs will work directly in a given patient. Researchers at the Heinz Nixdorf Chair for Medical Electronics at the Technische Universitaet Muenchen (TUM) have developed a new test process for cancer drugs.

22 Oct 2009

Advanced Liquid Logic awarded an NIAID contract to develop a rapid HIV diagnostic device

Advanced Liquid Logic announced today that it has received a large, four-year contract from the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health, for the development of a rapid, point-of-care, diagnostic device for the detection of HIV in low resource settings.

3 Oct 2009

UCF research team develops miniature diagnostic tool kit for dementia

With the risk of developing dementia growing at an alarming pace, a University of Central Florida research team is working with the Boston University School of Medicine to develop a miniature diagnostic toolkit in the hopes of stimulating earlier detection and treatment.

1 Oct 2009

SFC Fluidics to develop handheld traumatic brain injury diagnostic device for the U.S. Army

SFC Fluidics, LLC recently announced it has received a contract for approximately $5 million from the Congressionally Directed Medical Research Program for development of a handheld device for rapid diagnosis of traumatic brain injury (TBI). More than 1.5 million Americans suffer head injuries each year, and TBI has become a signature injury for American troops serving in the wars in Iraq and Afghanistan.

30 Sep 2009

An overview on nanoparticles

At SINTEF scientist both exploit the benefits of the nanotechnology and try to discover how tiny particles could behave hazardous in nature.

28 Sep 2009

Lab-on-a-chip performs 1,000 chemical reactions at once

Flasks, beakers, and hot plates may soon be a thing of the past in medicinal chemistry labs. Instead of handling a few experiments on a benchtop, scientists may simply pop a microchip into a computer and instantly run thousands of chemical reactions, with results literally shrinking the lab down to the size of a thumbnail.

From Siemens Healthineers 23 Sep 2009

Nanogap sensor array for ultra-sensitive detection of human DNA

Researchers in Singapore are reporting development of a new electronic sensor that shows promise as a faster, less expensive, and more practical alternative than tests now used to detect DNA. Such tests are done for criminal investigation, disease diagnosis, and other purposes.

27 Aug 2009

University of Southampton develops a microfluidic single-cell impedance cytometer for blood cell analysis

A hand-held device which could offer point-of-care blood cell analysis in doctors' surgeries is being developed by academics at the University of Southampton and is described in a paper in Lab on a Chip this month.

25 Aug 2009

New microchip technology may accelerate drug discovery for cancer, other diseases

Flasks, beakers and hot plates may soon be a thing of the past in chemistry labs. Instead of handling a few experiments on a bench top, scientists may simply pop a microchip into a computer and instantly run thousands of chemical reactions, with results - literally shrinking the lab down to the size of a thumbnail.

From Siemens Healthineers 3 Aug 2009

Music drives experimental samples through a lab-on-a-chip

Music, rather than electromechanical valves, can drive experimental samples through a lab-on-a-chip in a new system developed at the University of Michigan. This development could significantly simplify the process of conducting experiments in microfluidic devices.

27 Jul 2009

New ultra-sensitive device detects viruses in minutes

Imagine being able to detect in just a few minutes whether someone is infected with a virus. This has now become a reality, thanks to a new ultra-sensitive detector that has been developed by Ostendum, a spin-off company of the University of Twente.

28 May 2009

Novel "lab on a tube" monitoring device

The need for improved monitoring of neurotrauma patients has resulted in the development of a prototype of a novel, multitasking "lab on a tube" at the University of Cincinnati (UC).

4 May 2009

Microfluidic device mimics tumor microenvironment, helps drug discovery

One of the challenges that cancer researchers face in designing new antitumor agents is that of predicting how drug molecules will behave in the complex microenvironment that surrounds a tumor. In particular, tumors create all sorts of chemical and physical barriers that limit how much drug is able to enter a tumor, let alone reach cells deep within a tumor.

23 Feb 2009

Life-giving technology: Camera pills and ultrasound creating maps of the body

For more than ten years, senior medical officer Ronald Marvik at St. Olav's Hospital in Trondheim has been collaborating with SINTEF scientist Thomas Lango. Together, they have created a new IT-base window on the inside of the body, a window that makes a patient transparent on a screen when a surgeon inserts operating instruments through small openings in the abdominal wall.

23 Feb 2009

Tiny cell cultivation chamber of silicon plastic opens new potential in tumor research

Researchers at Uppsala University have developed a new tool that makes it possible to study the signals in the body that control the generation of blood vessels.

22 Feb 2009