Laboratory News and Research

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Robot designed to shoot X-ray video of sufferers of orthopedic injuries as they walk

The MRI and CT scan may one day have a robotic cousin capable of following and peering into patients as they move around.

23 Jan 2006

First genome-wide screen for protein complexes is completed

Researchers in Germany have finished the first complete analysis of the "molecular machines" in one of biology's most important model organisms: S. cerevisiae (baker's yeast). The study from the biotechnology company Cellzome, in collaboration with the European Molecular Biology Laboratory (EMBL), appears in this week's online edition of Nature.

23 Jan 2006

Novel compound stops brain cell degeneration in Alzheimer's disease

Drug discovery researchers at Northwestern University have developed a novel orally administered compound specifically targeted to suppress brain cell inflammation and neuron loss associated with Alzheimer's disease.

22 Jan 2006

Indonesians deaths bring bird toll to 82

According to a senior official at the Indonesian Health Ministry, a Hong Kong laboratory has confirmed that two children from the same Indonesian family have died from the H5N1 strain of bird flu this month.

22 Jan 2006

Caretek Medical signs feasibility agreement with major pharma for protein based drug

Caretek Medical Ltd, an Oxford-based company developing an innovative needle-free drug delivery system, today announced that it has signed a feasibility study agreement with a major global pharmaceutical company.

19 Jan 2006

Lab-on-chip can detect bird flu in humans

European microchip maker STMicroelectronics is planning to market a disposable laboratory microchip that can confirm within about an hour a human case of bird flu.

18 Jan 2006

TCF21 gene shown to be a tumor suppressor

Researchers have identified a new and unusual tumor suppressor gene that may be important in cancers of the lung and head and neck. The study shows that restoring the inactivated gene can slow the growth of tumor cells.

18 Jan 2006

Mutated oncogene triggers aggressive breast cancer

Researchers at Dana-Farber Cancer Institute have identified a molecular interaction that triggers a particularly aggressive form of breast cancer, and suggest that attacking this target with selective drugs might improve treatment.

18 Jan 2006

Handheld Doppler ultrasound technology finds veins quickly

When medics are treating trauma patients, every second counts. Yet bruises, burns, and other physical conditions often make it difficult to locate veins and administer lifesaving drugs or solutions.

18 Jan 2006

Retinal degeneration - researchers advance understanding

Researchers have labored for decades to understand blindness-inducing neurodegenerative diseases such as age-related macular degeneration (AMD) and retinitis pigmentosa (RP).

18 Jan 2006

Bexarotene shows promise in cancer treatment.

Researchers at Washington University School of Medicine in St. Louis now report that a compound related to vitamin A shows promise in preventing or slowing tumor growth in mice prone to lung cancer. The compound, called bexarotene, doesn't cause the severe skin irritations that have limited the use of other vitamin A derivatives in cancer therapies.

18 Jan 2006

Genetic risk factor for West Nile virus infection identified

People who lack a cell surface protein called CCR5 are highly resistant to infection by HIV but may be at increased risk of developing West Nile virus (WNV) illness when exposed to the mosquito-borne virus, report researchers from the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH).

18 Jan 2006

Missing protein C/EBPb may be cause of infertility

The absence of a key protein may lead to infertility. Researchers at the University of Illinois at Urbana-Champaign report that experiments involving mice -- to be detailed in the Proceedings of the National Academy of Sciences -- indicate that the transcription factor protein C/EBPb must be present in the uterus for pregnancy to occur.

18 Jan 2006

Turmeric and cauliflower prevents prostate cancer

According to researchers at Rutgers University, New Jersey, the curry spice turmeric has the potential for the treatment and prevention of prostate cancer.

17 Jan 2006

Dietary soy isoflavones inhibit estrogen effects in the postmenopausal breast

Research in monkeys suggests that the natural plant estrogens found in soy do not increase markers of breast cancer risk in postmenopausal women. In fact, they may provide a protective effect in some women. The research is reported in Cancer Research.

16 Jan 2006

Target identified for therapeutic drugs to fight adult brain cancer

A research team at UT Southwestern Medical Center has discovered a cell-signaling mechanism instrumental in the most common brain cancer in adults.

16 Jan 2006

Turmeric holds real potential for the treatment and prevention of prostate cancer

Rutgers researchers have found that the curry spice turmeric holds real potential for the treatment and prevention of prostate cancer, particularly when combined with certain vegetables.

16 Jan 2006

18 in Turkey with bird flu

According to the World Health Organisation (WHO) the number of people who have now fallen victim to the deadly bird flu virus in Turkey has risen to 18 from 15, and most of them are children.

16 Jan 2006

DinB DNA polymerase is a key player in DNA repair

A quarter century after they discovered it, researchers have identified the job of one of the most common DNA-damage response proteins. The enzyme has puzzled scientists because it is present in nearly every organism, which suggests that it is crucial to life, and yet, in laboratory experiments, its function has remained a mystery.

11 Jan 2006

Segregation of the brain into gray and white matter

By borrowing mathematical tools from theoretical physics, scientists have recently developed a theory that explains why the brain tissue of humans and other vertebrates is segregated into the familiar "gray matter" and "white matter."

11 Jan 2006