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Chemotherapy for brain tumors is boosted after vaccine targets resistance-related TRP-2 antigen

In the August issue of the journal Oncogene, researchers at Cedars-Sinai Medical Center's Maxine Dunitz Neurosurgical Institute describe a molecular mechanism that appears to make malignant brain tumors more vulnerable to chemotherapy after they have been treated with the dendritic cell vaccine.

13 Jun 2005

Scientists create new brain cells - in a dish

Regenerative medicine scientists at the University of Florida's McKnight Brain Institute have created a system in rodent models that for the first time duplicates neurogenesis - the process of generating new brain cells - in a dish.

13 Jun 2005

Perceptual learning can have a cost

Our ability to learn to see things that may be new or unfamiliar to us is a plus; it allows us to adapt to changes in our surrounding environment.

13 Jun 2005

Researchers may be on the verge of exploiting the vulnerabilities of a virus that causes cervical cancer

Researchers may be on the verge of exploiting the vulnerabilities of a virus that causes cervical cancer, thanks to a newly developed technique that enables scientists to mass-produce human papillomavirus (HPV) in the laboratory.

13 Jun 2005

Research accelerates the search for an effective cancer vaccine

By devising a novel way to package the genome of a common human tumor virus - the virus that causes common warts, genital warts and that is implicated in prevalent cancers - scientists have paved the way for making the pathogen far more accessible to biomedical science.

13 Jun 2005

Psychosocial factors and interleukin-6 among women with advanced ovarian cancer

A new study funded by the National Cancer Institute reports that social support and other behavioral factors are related to levels of a circulating protein, which at high levels is associated with a poor prognosis in advanced ovarian cancer.

13 Jun 2005

Bio-engineered skin provides clues to melanoma development

When it comes to the deadly skin cancer melanoma, studying functional tissue rather than cell lines may better provide insight into the disease's development, according to new research from a Howard Hughes Medical Institute predoctoral fellow at Stanford University School of Medicine.

12 Jun 2005

Link between PKC enzyme and kidney disease in diabetes confirmed

Researchers at Joslin Diabetes Center have investigated PKC-beta - a critical enzyme implicated in the devastating complications of type 1 and type 2 diabetes - for more than two decades.

12 Jun 2005

Mad cow disease found in animal in the U.S.

In disturbing news this week, Agriculture Secretary Mike Johanns said a U.S. animal has tested positive for mad cow disease.

12 Jun 2005

Link between hyperglycemia (high blood glucose), overexpression of PKC-beta 2 and kidney disease

Scientists at Joslin Diabetes Center have investigated PKC-beta -- a critical enzyme implicated in the devastating complications of type 1 and type 2 diabetes -- for more than two decades.

10 Jun 2005

Researchers resurrect old technology to quickly and accurately identify deadly bacterial infections in hospital patients

University of Florida researchers are resurrecting an old technology to more quickly and accurately identify potentially deadly bacterial infections in hospital patients.

10 Jun 2005

If a dividing cell's activity is a pop song, then the same process in an immune cell is an extended-play dance remix

The basics of cell division are the same in both, but there's a heck of a lot more going on in immune cells, Johns Hopkins scientists have discovered.

10 Jun 2005

European approval of Temodal (temozolomide) capsules for treatment of glioblastoma multiforme

Schering-Plough announced today that the European Commission has granted approval of Temodal (temozolomide) Capsules for first-line use for the treatment of patients with newly diagnosed glioblastoma multiforme (GBM), the most common and aggressive form of primary brain cancer.

10 Jun 2005

AIDS expert says global strategy needed to combat feminization of HIV/AIDS

Thomas C. Quinn, M.D., a Johns Hopkins physician and scientist, who has spent the best part of the last 25 years leading major efforts to combat HIV and AIDS throughout the world, is calling for global strategies and resources to confront the rapid "feminization" of the AIDS pandemic.

10 Jun 2005

Urgent call for global strategies and resources to confront the rapid "feminization" of the AIDS pandemic

In an article appearing in the journal Science online June 10, Thomas C. Quinn, M.D., professor of infectious diseases at Hopkins and a senior investigator at the National Institute of Allergy and Infectious Disease, reports that women have in the last 20 years moved from those least affected by HIV to those in whom the disease is spreading fastest.

10 Jun 2005

Scientists produce for the first time an infectious form of the hepatitis C virus in laboratory cultures of human cells

The finding, reported in the June 9 issue of Science Express, will allow scientists to study every stage of the HCV life cycle and develop drugs to treat this life-threatening disease that affects more than 170 million people around the world.

9 Jun 2005

Experimental drug works best in combination with older remedy for Alzheimer's disease and other dementias

An experimental drug combined with an already-popular memory-enhancing compound may further delay memory loss in patients with Alzheimer's disease and other dementias, Johns Hopkins University scientists, in collaboration with researchers from University of North Carolina, have found.

9 Jun 2005

Study of glial cells in the roundworm C. elegans may provide insight into a variety of human brain diseases

The key to understanding our brains may lie within a one-millimeter long worm, new research from Rockefeller University indicates. Reporting in the June issue of Developmental Cell, Shai Shaham, Ph.D., and graduate student Elliot Perens use the roundworm, C. elegans, to investigate the mysterious glial cell, which makes up 90 percent of the human brain and, when it malfunctions, can contribute to diseases like Parkinson's disease and schizophrenia.

9 Jun 2005

Australia aims to combat zoonotic diseases

Australian Parliamentary Secretary for Foreign Affairs and Trade, Bruce Billson, announced this week in Jakarta, a further $6 million to help combat avian influenza in the region through increased sharing of Australian expertise and support for World Health Organisation detection and response capabilities.

9 Jun 2005

Research opens up new directions for studying prion diseases in humans

The mysterious, highly infectious prions, which cause the severe destruction of the brain that characterizes "mad cow disease" and several human brain degenerative disorders, can be rendered harmless in the laboratory by a slight alternation of the three-dimensional conformation or shape of the prion protein's structure.

9 Jun 2005

Laboratory News and Research

Chemotherapy for brain tumors is boosted after vaccine targets resistance-related TRP-2 antigen

Scientists create new brain cells - in a dish

Perceptual learning can have a cost

Researchers may be on the verge of exploiting the vulnerabilities of a virus that causes cervical cancer

Research accelerates the search for an effective cancer vaccine

Psychosocial factors and interleukin-6 among women with advanced ovarian cancer

Bio-engineered skin provides clues to melanoma development

Link between PKC enzyme and kidney disease in diabetes confirmed

Mad cow disease found in animal in the U.S.

Link between hyperglycemia (high blood glucose), overexpression of PKC-beta 2 and kidney disease

Researchers resurrect old technology to quickly and accurately identify deadly bacterial infections in hospital patients

If a dividing cell's activity is a pop song, then the same process in an immune cell is an extended-play dance remix

European approval of Temodal (temozolomide) capsules for treatment of glioblastoma multiforme

AIDS expert says global strategy needed to combat feminization of HIV/AIDS

Urgent call for global strategies and resources to confront the rapid "feminization" of the AIDS pandemic

Scientists produce for the first time an infectious form of the hepatitis C virus in laboratory cultures of human cells

Experimental drug works best in combination with older remedy for Alzheimer's disease and other dementias

Study of glial cells in the roundworm C. elegans may provide insight into a variety of human brain diseases

Australia aims to combat zoonotic diseases

Research opens up new directions for studying prion diseases in humans

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