Laboratory News and Research

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Ultrasound to view heart's interior in three dimensions

Duke University engineers are developing technology that may enable physicians to someday use high frequency ultrasound waves both to visualize the heart's interior in three dimensions and then selectively destroy heart tissue with heat to correct arrhythmias.

7 Nov 2005

HIV antiretroviral therapy does help those in third world

With preliminary results from a study in Botswana, Harvard School of Public Health researchers have found that people with HIV-1 subtype C in resource-poor settings, who receive antiretroviral (ARV) therapy, can achieve comparable results to those in the developed world.

7 Nov 2005

BRAF gene mutations predict sensitivity to a new class of drug

A team of researchers led by scientists at Memorial Sloan-Kettering Cancer Center have discovered that a new class of drugs -- now in early stage clinical trials -- work best in patients with mutations in the BRAF gene.

7 Nov 2005

New high-resolution data on intact ribosome

A new, sharper picture of the nano-machine that translates our genetic program into proteins promises to help researchers explain how some types of antibiotics work and could lead to the design of better ones.

7 Nov 2005

New discovery helps explain complex neurocircuitry behind body weight control

A study led by a scientific team at Beth Israel Deaconess Medical Center (BIDMC) provides another important step in our understanding of the critical role that the brain's molecular pathways play in the development of obesity and related disorders.

7 Nov 2005

Scientists find new mechanism by which brain cells can be damaged during chronic neurodegenerative diseases

Scientists at the University of Rochester Medical Center have targeted a new culprit and method of attack on neurologic functions in diseases such as Alzheimer's and dementia associated with HIV.

7 Nov 2005

Mongolian birds provide Avian influenza virus samples

Avian influenza virus samples collected from wild birds in Mongolia by field veterinarians from the New York City-based Wildlife Conservation Society (WCS) have been selected by the World Health Organization to be part of a new human pandemic influenza vaccine currently in development.

7 Nov 2005

Novel technique to remove tumors from the cervical region of the spine

University of California - San Francisco (UCSF) surgeons are using a novel technique to remove tumors from the cervical region of the spine that were previously thought "inoperable."

7 Nov 2005

Ospemifine may also help to prevent breast cancer

A tamoxifen-like drug developed by UC Davis and Finnish researchers, now in clinical testing as a treatment for vaginal atrophy, may also help to prevent breast cancer, two preliminary studies suggest.

3 Nov 2005

Rapid screen-and-treat methods significantly reduce cervical cancer precursor lesions

A new study led by Columbia University Medical Center researchers demonstrates the safety and efficacy of two low-tech diagnostic tools to significantly reduce the prevalence of cervical cancer precursor lesions.

3 Nov 2005

New targeted cancer drug delivery system

Prostate, breast and other cancer patients may be offered a new, stauncher targeted drug delivery system to treat their diseases in the next decade.

3 Nov 2005

New method to find deadly malaria parasite

Researchers at UCSD have discovered that the single-cell parasite responsible for an estimated 1 million deaths per year worldwide from malaria has protein "wiring" that differs markedly from the cellular circuitry of other higher organisms

3 Nov 2005

DN-101 may protect against major side effects of chemotherapy

Men with advanced prostate cancer who take an experimental, high-dose vitamin D pill with chemotherapy live about eight months longer than those receiving chemotherapy and placebo, according to a new study.

3 Nov 2005

Calcitriol - promising chemopreventive agent that may prevent prostate cancer

The active metabolite of vitamin D, calcitriol, and other vitamin D analogs are promising chemopreventive agents that may prevent prostate cancer, according to a study presented today at the American Association for Cancer Research's 4th annual Frontiers in Cancer Prevention Research meeting in Baltimore.

3 Nov 2005

Simple, at-home treatment for jet lag

A simple, at-home treatment -- a single light box and the over-the-counter drug melatonin -- allows travelers to avoid jet lag by resetting their circadian body clock before crossing several time zones, according to new research being published in The Endocrine Society's Journal of Clinical Endocrinology and Metabolism.

3 Nov 2005

Diet high in soy does not increase the risk of uterine cancer in postmenopausal women

Cline said there has been much debate about whether high levels of dietary soy are safe for postmenopausal women. Soy products are sometimes sold as a natural alternative to traditional estrogen therapy, which does increase the risk of endometrial cancer.

3 Nov 2005