Leptin News and Research

RSS

Leptin is a 16 kDa protein hormone that plays a key role in regulating energy intake and energy expenditure, including appetite and metabolism. It is one of the most important adipose derived hormones. The ''Ob(Lep)'' gene (Ob for obese, Lep for leptin) is located on chromosome 7 in humans.

Bardet-Biedl syndrome provides clues on obesity, blood pressure

University of Iowa researchers have found a clue about how resistance to the hormone leptin might disrupt the brain signals that tell the body when to stop eating.

4 Mar 2008

Leptin which suppresses hunger could be the way to beat obesity

Australian scientists say a hormone that suppresses hunger may be far more powerful when it comes to weight loss than first thought.

26 Feb 2008

Metabolic syndrome linked to climate

Researchers from the University of Chicago have discovered that many of the genetic variations that have enabled human populations to tolerate colder climates may also affect their susceptibility to metabolic syndrome, a cluster of related abnormalities such as obesity, elevated cholesterol levels, heart disease, and diabetes.

17 Feb 2008

Predisposition for obesity might be wired into the brain

A predisposition for obesity might be wired into the brain from the start, suggests a new study of rats in the February issue of Cell Metabolism, a publication of Cell Press.

7 Feb 2008

New discoveries on what does and doesn't affect immune system

Scientists know that a number of factors can affect the body's immune system: poor diet, certain steroids, chronic stress. Now researchers at Michigan State University have discovered that an appetite-controlling hormone also affects the immune system, while natural versions of certain steroids do not.

4 Feb 2008

Body fat protein adiponectin plays role in tumour growth

Scientists have discovered how low levels of a protein hormone found in body fat, plays a crucial role in tumour growth and spread. Their findings are published in a paper in the British Journal of Cancer.

31 Jan 2008

Adaptive functional evolution of leptin in cold-adaptive pika family

Researchers at the Northwest Institute of Plateau Biology, Chinese Academy of Sciences have put forward the viewpoint for the first time that adaptive functional evolution may occur in the leptin protein of the pika (Ochotona) family, a typical cold-adaptive mammal.

24 Jan 2008

New understanding of the link between heart disease and belly fat

By now, everyone knows that overweight people have a higher risk of heart attacks, strokes and other problems that arise from clogged, hardened arteries. And people who carry their extra weight around their waist - giving them a "beer belly" or an "apple" shape - have the highest risk of all.

22 Jan 2008

Pregnant women who are overweight/obese set the stage for offspring's obesity risk

The number of overweight and obese Americans continues to grow rapidly. Today, 50 percent of adults are overweight and up to 20 percent are obese. While the number of overweight/obese children is at an all time high, the steady increase of overweight infants -- individuals under 11 months old -- is alarming.

4 Jan 2008

Children short of sleep three times as likely to be obese

According to new research by scientists in New Zealand children who do not get enough sleep face an increased risk of obesity and behavioral problems.

2 Jan 2008

Cheaper drugs now closer to realization with new DropArray technology

A standard laboratory tool for measuring pharmacological activity of biological substances and performing other related tests may soon be replaced by a new miniaturized bioassay that will be faster, cheaper and more efficient for scientists to use, with new technology developed by Singapore's Institute of Bioengineering and Nanotechnology (IBN).

17 Dec 2007

Predicting growth hormone treatment success

Growth hormone treatments work better on some children than on others, but judging which candidates will gain those vital inches in height is no simple task.

13 Dec 2007

Likelihood of falling pregnant steadily decreases the fatter a woman is

A new study of obesity and the probability of pregnancy has shown that a woman's chances of a spontaneous pregnancy steadily decrease the fatter she is.

13 Dec 2007

Effects of weight, genetics and religious beliefs on prostate cancer

African-American men face an observable disadvantage versus Caucasian men when it comes to prostate cancer survival.

29 Nov 2007

Childhood BMI rebound influences heart disease late in life

The earlier in life children reach their lowest body mass index (BMI) signals potential heart disease risk factors and may become evident as early as age 7, researchers reported at the American Heart Association's Scientific Sessions 2007.

6 Nov 2007

U-M study finds shorter sleep duration for 9- to 12-year-old kids is associated with increased risk for being overweight

Diets high in fat and sugar may not be the only things contributing to American children's expanding waistlines. Research findings from the University of Michigan C.S. Mott Children's Hospital suggest that kids who aren't getting enough sleep also may be at an increased risk for being overweight.

5 Nov 2007