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Novel dietary tool aims to help cancer patients fight disease

A new dietary tool to quickly and accurately assess micronutrient levels aims to help cancer patients fight disease, paving the way to find better nutritional solutions for oncology services, Flinders University researchers say.

8 Feb 2022

Representative structures of SARS-CoV-2 and development of therapeutic agents for targeting these proteins

Researchers from China summarized the representative structures of SARS-CoV-2 proteins and discussed the development of novel therapeutic agents for targeting these proteins to treat and prevent COVID-19.

2 Feb 2022

A substrate envelope approach to examine drug resistance potential of SARS-CoV-2 Mpro

A team of scientists from the United States has recently defined the substrate envelop of the main protease of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The study is currently available on the bioRxiv* preprint server while awaiting peer review.

31 Jan 2022

Human LRRC15 protein is an inhibitory receptor for SARS-CoV-2 spike-mediated entry

In a recent study, published on the bioRxiv* preprint server, researchers identified human LRRC15 as an inhibitory receptor for SARS-CoV-2 entry, which directly binds to the receptor-binding domain (RBD) of the spike protein with a moderate affinity and inhibits spike-mediated entry.

29 Nov 2021

Novel influenza vaccine candidate shows promise

Researchers investigate the potential value of a new vaccine candidate for the influenza virus.

29 Nov 2021

Discovery of new receptor that interacts with SARS-CoV-2 spike, suppresses infection

Researchers recently conducted a study to identify host factors affecting cellular interactions of the SARS-CoV-2 spike protein.

16 Nov 2021

Identification of a candidate effector gene at COVID-19 risk locus

A new study focuses on developing a comprehensive platform to decode the effects of sequence variation identified by GWAS.

8 Nov 2021

Immune evasion by SARS-CoV-2 facilitated by a mutational hotspot in the NTD

Researchers discuss mutations in the NTD of the spike protein, which contains an antigenic “supersite” and is the target for nAbs.

24 Oct 2021

Researchers discover protein previously unknown to be involved in SARS-CoV-2 infection

Researchers in the UK and Germany have provided evidence for a novel mechanism by which severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19) – binds to human host cells.

27 Sep 2021

Review of COVID-19 clinical and viral characteristics, pathogenesis, and genetics

A new review article investigates the clinical and viral characteristics, pathogenesis, as well as human genetic basis associated with COVID-19.

27 Sep 2021

New SARS-CoV-2 mechanism of host gene suppression

A new study finds that the viral non-coding RNA dubbed vmiR-5p, derived from the viral gene ORF7a, appears to reduce host transcription.

13 Sep 2021

Study investigates the effects of calycosin on breast cancer cell progression

Aging-US published "Calycosin inhibits breast cancer cell migration and invasion by suppressing EMT via BATF/TGF-β1" which reported that in this study, the authors investigated the effects of calycosin on breast cancer cell progression and their underlying mechanisms. Calycosin dose- and time-dependently inhibited proliferation, migration, and invasion by T47D and MCF-7 breast cancer cells by downregulating basic leucine zipper ATF-like transcription factor expression.

23 Aug 2021

Leucine News and Research

Novel dietary tool aims to help cancer patients fight disease

Representative structures of SARS-CoV-2 and development of therapeutic agents for targeting these proteins

A substrate envelope approach to examine drug resistance potential of SARS-CoV-2 Mpro

Human LRRC15 protein is an inhibitory receptor for SARS-CoV-2 spike-mediated entry

Novel influenza vaccine candidate shows promise

Discovery of new receptor that interacts with SARS-CoV-2 spike, suppresses infection

Identification of a candidate effector gene at COVID-19 risk locus

Immune evasion by SARS-CoV-2 facilitated by a mutational hotspot in the NTD

Researchers discover protein previously unknown to be involved in SARS-CoV-2 infection

Review of COVID-19 clinical and viral characteristics, pathogenesis, and genetics

New SARS-CoV-2 mechanism of host gene suppression

Study investigates the effects of calycosin on breast cancer cell progression

L452R mutations may have triggered the emergence of several COVID-19 variants

Temple researchers receive $1.25M NIH grant to advance understanding of neurodegenerative diseases

Dileucine more effective than leucine in stimulating muscle-building in humans

Activation of NLRP3 inflammasome by the N protein of SARS-CoV-2 to induce hyperinflammation

Pfizer moves towards an oral anti-COVID-19 therapy

Injecting mice with pulmonary endothelial cells can reverse symptoms of emphysema

Can saliva metabolomics predict COVID-19 severity?

A World First: sequencing polyclonal antibodies using only proteomics

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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