Leukocyte News and Research

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Why organs fail following massive trauma

Massive trauma, say from a sabertooth tiger attack, meant immediate death for the primitive human.

17 Oct 2006

Vaccine that protects mice against 1918 influenza virus developed

Federal scientists have developed a vaccine that protects mice against the killer 1918 influenza virus. They also have created a technique for identifying antibodies that neutralize this virus, a tool that could help contain future pandemic flu strains.

17 Oct 2006

New technique detects signature of metastasizing melanoma with as few as 10 cancer cells present in blood sample

Researchers at the University of Missouri-Columbia can now detect the spread of skin cancer cells through the blood by literally listening to their sound.

16 Oct 2006

New York Times examines efforts to obtain FDA approval for Abraxane to treat earlier-stage cancer

The New York Times has examined efforts by the pharmaceutical company Abraxis BioScience to obtain FDA approval for its late-stage breast cancer drug Abraxane as a treatment for earlier-stage breast cancer.

5 Oct 2006

Imperial receives $4 million for glycomics research

A team of researchers from Imperial College London's Division of Molecular Biosciences has received a grant of over US $4 million to support a research facility for understanding how sugars are involved in cell to cell communication.

28 Sep 2006

Study reveals white blood cells can both hurt and help transplanted kidneys

In an example of biological irony, the same white blood cell chemistry known to damage kidneys used for transplants may also help prevent such damage, according to a federally funded study in genetically engineered mice at Johns Hopkins.

21 Sep 2006

FDA approves Noxafil (posaconazole) to prevent invasive fungal infections

The U.S. Food and Drug Administration has approved Noxafil (posaconazole) to prevent fungal infections caused by certain molds and yeast-like fungus called Aspergillus and Candida.

19 Sep 2006

Researchers create roadmap to integrin activation

Calling it an important technical advance in the study of the complex receptors and pathways of the body's cellular system, researchers at the University of California, San Diego (UCSD) School of Medicine have reconstructed the signaling pathways that impact activation of a receptor that is critical to the control of bleeding and to the thrombosis that occurs in heart attacks and strokes.

18 Sep 2006

GRK2 protein -a potential biomarket for heart failure

A team of cardiology researchers at Thomas Jefferson University has determined that GRK2, a protein that plays an important regulatory role in heart failure, is elevated in patients with failing hearts when compared to patients with normal heart function.

12 Sep 2006

Weakened immune response resulting from HIV infection can lead to trouble when it comes to treating malaria

"Our study demonstrates that HIV-1 infected patients with suppressed immunity represent, next to children and pregnant women, an additional vulnerable group for malaria," says Jean-Pierre Van geertruyden, MD, MSc, lead author of the article.

7 Sep 2006

UIC receives $20 million NCI grant to research blood disorders

A $19.6 million National Cancer Institute grant has been awarded to the University of Illinois at Chicago College of Medicine to advance basic and clinical research for incurable blood disorders.

6 Sep 2006

Researchers identify genetic risk for type 1 diabetes

A discovery at the Barbara Davis Center for Childhood Diabetes has identified a genetic risk for type 1 diabetes three to four times higher than previously thought possible.

4 Sep 2006

Individuals with major depression have an exaggerated inflammatory response to psychological stress

Individuals with major depression have an exaggerated inflammatory response to psychological stress compared to those who do not suffer from depression, according to a study by researchers at Emory University School of Medicine.

4 Sep 2006

New method of gene therapy alters immune cells for treatment of advanced melanoma

A team of researchers at the National Cancer Institute (NCI), part of the National Institutes of Health, has demonstrated sustained regression of advanced melanoma in a study of 17 patients by genetically engineering patients' own white blood cells to recognize and attack cancer cells.

4 Sep 2006

New cell-based targets for treating autoimmune inflammatory diseases

Patients with systemic autoimmune diseases such as lupus and rheumatoid arthritis (RA) often suffer loss of kidney function.

31 Aug 2006

FDA approves Plavix for STEMI heart attacks

The Food and Drug Administration (FDA) today approved the use of Plavix (clopidogrel bisulfate) for patients who have had a type of heart attack called acute ST-segment elevation myocardial infarction (STEMI), who are not going to have coronary artery repair (angioplasty).

17 Aug 2006