Lewy Bodies News and Research

RSS

Study reveals a detrimental role of the immune system in Lewy body dementias

T-cells respond to buildups of alpha-synuclein, the aggregated protein clumps that are a feature of neurodegenerative diseases including dementia with Lewy bodies and Parkinson's disease (PD), according to a Northwestern Medicine study published in Science.

14 Oct 2021

$35.1 million US grant focuses on investigating sleep disorder linked to neurodegeneration

People with rapid eye movement (REM) sleep behavior disorder act out their dreams. While sleeping safely in bed, for example, they might throw up their arms to catch an imaginary ball, or try to run from an illusory assailant.

5 Oct 2021

Nasal drugs show success in slowing Parkinson's disease progression in mice

Potential new treatments for Parkinson's disease developed by researchers at Rush University Medical Center have shown success in slowing progression of the disease in mice.

21 Sep 2021

Study reinforces that dementia with Lewy bodies can be classified into two different disease types

Results obtained in a study recently completed at the University of Helsinki and Helsinki University Hospital reinforce the notion that dementia with Lewy bodies can be pathologically classified into two different disease types.

8 Sep 2021

Study reveals the implication of lysosomes in the spread of Parkinson’s disease

Over the last few decades, neurodegenerative diseases became one of the top 10 global causes of death. Researchers worldwide are making a strong effort to understand neurodegenerative diseases pathogenesis, which is essential to develop efficient treatments against these incurable diseases.

23 Jul 2021

Autophagy disruption may be at the root of early cognitive changes in Huntington’s disease

Huntington's Disease (HD) is a progressive neurodegenerative condition characterized by motor, cognitive, and psychiatric symptoms, and motor symptoms are often preceded by cognitive changes.

15 Jul 2021

Promising preclinical results of new dementia treatment candidate set the stage for human trials

Researchers have identified a new treatment candidate that appears to not only halt neurodegenerative symptoms in mouse models of dementia and Alzheimer's disease, but also reverse the effects of the disorders.

29 Jun 2021

Researchers develop integrative approach to better understand the origins of Parkinson's disease

Parkinson's disease is the second most common neurodegenerative disease and affects more than 10 million people around the world.

19 May 2021

Study indicates an amyloid link between melanoma and Parkinson’s disease

On the surface, Parkinson's disease -; a neurodegenerative disorder -; and melanoma -; a type of skin cancer -; do not appear to have much in common.

7 Apr 2021

Neuroinvasiveness of SARS-CoV-2 shown by viral RNA and inflammation in the brain

A new study describes the results of a macaque study that showed the development of neurological features of inflammation, following infection by SARS-CoV-2.

25 Feb 2021

Lewy body dementia may share similar genetic profiles with Alzheimer's disease

In a study led by National Institutes of Health (NIH) researchers, scientists found that five genes may play a critical role in determining whether a person will suffer from Lewy body dementia, a devastating disorder that riddles the brain with clumps of abnormal protein deposits called Lewy bodies.

17 Feb 2021

Study unravels function of 'mystery protein' that kills brain cells of people with Parkinson's

A study published in Nature Communications today (Wednesday 10 February) presents compelling new evidence about what a key protein called alpha-synuclein actually does in neurons in the brain.

10 Feb 2021

Imaging technique can differentiate Alzheimer's disease from dementia with Lewy bodies

Scientists in Portugal and the United Kingdom were able to confirm that an imaging technique that traces neuronal dopaminergic deficiency in the brain is able to differentiate, in vivo, Alzheimer's disease from lesser-known dementia with Lewy bodies.

5 Feb 2021

Anti-diabetic drug could be repurposed for treating Parkinson's disease

A hallmark of Parkinson's disease is the degeneration of a group of dopaminergic neurons in the brain, which play key roles in movement initiation and co-ordination.

24 Nov 2020

Study links brain astrocyte dysfunction to Parkinson’s disease pathology

A new study using induced pluripotent stem cell technology links astrocyte dysfunction to Parkinson’s disease pathology.

8 Sep 2020

Study reveals a promising treatment for Parkinson's disease

Scientists at the University Bath in the UK have discovered a series of protein structures that are thought to be highly relevant to the onset of Parkinson's disease.

20 Aug 2020

Study highlights a complex and under-recognized form of dementia

The long-running study on aging and brain health at the University of Kentucky's Sanders-Brown Center on Aging Alzheimer's Disease Center has once again resulted in important new findings - highlighting a complex and under-recognized form of dementia.

27 Jun 2020

AFFiRiS AG announces results of phase 1 trial with PD01A in Parkinson's

AFFiRiS AG, a clinical-stage biotechnology company developing novel disease-modifying specific active immunotherapies (SAITs), today announced that detailed results of the phase 1 clinical program with its lead candidate PD01 in early Parkinson's disease (PD) patients were published in the peer-reviewed journal The Lancet Neurology.

18 Jun 2020

AFFiRiS announces preclinical results of monoclonal antibody mAB C6-17 in Huntington's

AFFiRiS, a clinical-stage biotechnology company developing novel disease-modifying specific active immunotherapies, today announced that detailed preclinical results with its monoclonal antibody mAB C6-17 to treat Huntington's Disease were published in the peer-reviewed journal Neurobiology of Disease.

3 Jun 2020

Mutated ATP1B gene a risk factor for Parkinson’s

The brain consists of about 100 billion neurons that form a complex and interconnected network in our brain, allowing us to generate complex thought patterns and actions. These neurons or nerve cells are the functional units of the nervous system that process and transmit information around the body. Neurodegenerative diseases develop with the progressive loss of these neurons.

14 Apr 2020