Lipids News and Research

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Lipids are a broad group of naturally-occurring molecules which includes fats, waxes, sterols, fat-soluble vitamins (such as vitamins A, D, E and K), monoglycerides, diglycerides, phospholipids, and others. The main biological functions of lipids include energy storage, as structural components of cell membranes, and as important signaling molecules.

Inhibition of mitochondrial calcium uptake specifically toxic to cancer cells

Inhibiting the transfer of calcium ions into the cell's powerhouse is specifically toxic to cancer cells, according to an article published this week in Cell Reports by researchers from the Perelman School of Medicine at the University of Pennsylvania.

4 Mar 2016

Dietary broccoli may protect against liver cancer

Consumption of broccoli has increased in the United States over the last few decades as scientists have reported that eating the vegetable three to five times per week can lower the risk of many types of cancer including breast, prostate, and colon cancers.

4 Mar 2016

Polyunsaturated lipids can alter binding rate of two receptors involved in Parkinson's and Alzheimer's

A study published in the prestigious journal Scientific Reports from the Nature group demonstrates, for the first time and using computational tools, that polyunsaturated lipids can alter the binding rate of two types of receivers involved in certain nervous system diseases.

2 Mar 2016

University of Louisville cardiologist on the verge of breakthrough in predicting heart disease in women

Heart disease is the leading cause of mortality in women worldwide, including in the United States. Although deaths from cardiovascular disease (CVD) in men have declined since the 1970s, the rates of death for women have not followed.

1 Mar 2016

Researchers unravel biochemical action of antimalarial drug

Malaria is a worldwide menace. According to the Centers for Disease Control and Prevention, over 500,000 individuals died from malaria in 2013 alone. While treatments for the disease exist, cures can also take a hefty physical toll.

26 Feb 2016

New analytical tool may help diagnose cancer faster than conventional methods

Researchers have developed a new analytical tool for medical applications and biological research that might be used to diagnose cancer more rapidly than conventional methods.

26 Feb 2016

New Notre Dame research may lead to a therapy for Niemann-Pick Type C disease

Niemann-Pick Type C (NPC) disease is a rare, fatal neurodegenerative disease for which there is currently no cure. NPC primarily strikes children before and during adolescence and affects one in every 150,000 children. The disease causes cholesterol and other lipids to build up in the body's cells, which results in symptoms such as delayed motor development, deterioration of memory and balance, and seizures.

26 Feb 2016

Inadequate dietary intake of essential amino acids and nutrient choline linked to stunting

Worldwide, an estimated 25 percent of children under age 5 suffer from stunted growth and development. The most visible characteristic is short stature, but the effects of stunting are far more profound: The condition prevents children from reaching their cognitive potential; makes them more susceptible to illness and infection; and shortens their life spans.

24 Feb 2016

Virginia Tech scientist finds way to potentially track and stop viruses

Viruses are molecular thieves that take from their hosts under the cloak of darkness. But now a Virginia Tech scientist has found a way to not only track viral hijackers, but also potentially stop them from replicating.

19 Feb 2016

Beiging of white fat could be harnessed to combat diabetes

Researchers are getting closer to learning how to turn white fat cells into brown fat cells, in a process called "beiging," to bring down blood sugar levels and fight diabetes. The team, led by Joseph Baur, PhD, an assistant professor of Physiology in the Perelman School of Medicine at the University of Pennsylvania published their findings this month in the journal Diabetes.

18 Feb 2016

Beige-fat formation could be harnessed to fight diabetes

Researchers are getting closer to learning how to turn white fat cells into brown fat cells, in a process called "beiging," to bring down blood sugar levels and fight diabetes.

17 Feb 2016

Pioneering technique shows promise for new medical diagnostics, targeted drug delivery

Living systems rely on a dizzying variety of chemical reactions essential to development and survival. Most of these involve a specialized class of protein molecules--the enzymes.

12 Feb 2016

Study identifies FGF21 protein as potential therapeutic agent for cardiovascular diseases, type 2 diabetes

New research on the blood lipid-lowering protein FGF21 shows how it redistributes fatty acids by two distinct mechanisms. The discovery could lead to improved pharmaceutical treatment for type 2 diabetes and other obesity-related diseases.

11 Feb 2016

Yale Cancer Center researchers identify cause of myeloma

Yale Cancer Center researchers have identified what causes a third of all myelomas, a type of cancer affecting plasma cells. The findings, published in the Feb. 11 issue of the New England Journal of Medicine, could fundamentally change the way this cancer and others are treated.

11 Feb 2016

Researchers devise lipid-based diets to relieve symptoms of Alzheimer's disease

Alzheimer´s disease (AD) is the most common disease underlying memory problems and dementia in the elderly. One of the invariable pathologies in AD is degeneration of cholinergic synapses in brain cortex and hippocampus.

11 Feb 2016

Experimental nanoparticle therapy shows promise for fighting primary liver cancer

An experimental nanoparticle therapy that combines low-density lipoproteins (LDL) and fish oil preferentially kills primary liver cancer cells without harming healthy cells, UT Southwestern Medical Center researchers report.

9 Feb 2016

Study provides new insight into complex interchange that can raise blood levels of fat in type 1 diabetes

Researchers have new insight into the complex interchange that can raise blood levels of unhealthy lipids, or fat, in type 1 diabetes, and early evidence that a drug under study to block cancer cell growth can restore healthier levels.

8 Feb 2016

New technology could help identify, characterize biologically active molecules produced by living cells

Gene sequencing company Illumina recently made big waves by announcing a new spinoff, Grail, dedicated to building a test for cancer by sequencing tumor DNA fragments found in blood. The company also reported plans for a separate project to identify single cells and tag them for later analysis.

1 Feb 2016

Mild reduction in food intake slows development of autosomal-dominant polycystic kidney disease

A small reduction in food intake—less than required to cause weight loss—dramatically slowed the development of a common genetic disorder called autosomal-dominant polycystic kidney disease (ADPKD) in mice, a new study in American Journal of Physiology—Renal Physiology reports.

30 Jan 2016

Sphingosine kinase inhibitor slows castration-resistant prostate cancer cell growth

A first-in-class sphingosine kinase 2 inhibitor slowed the growth of castration-resistant prostate cancer cells, in part by inhibiting the enzyme dihydroceramide desaturase (DEGS), but did not kill them, according to the results of preclinical in vitro and in vivo studies published in the December 2015 issue of Molecular Cancer Therapeutics by researchers at the Medical University of South Carolina and others.

30 Jan 2016

Lipids News and Research

Further Reading

Inhibition of mitochondrial calcium uptake specifically toxic to cancer cells

Dietary broccoli may protect against liver cancer

Polyunsaturated lipids can alter binding rate of two receptors involved in Parkinson's and Alzheimer's

University of Louisville cardiologist on the verge of breakthrough in predicting heart disease in women

Researchers unravel biochemical action of antimalarial drug

New analytical tool may help diagnose cancer faster than conventional methods

New Notre Dame research may lead to a therapy for Niemann-Pick Type C disease

Inadequate dietary intake of essential amino acids and nutrient choline linked to stunting

Virginia Tech scientist finds way to potentially track and stop viruses

Beiging of white fat could be harnessed to combat diabetes

Beige-fat formation could be harnessed to fight diabetes

Pioneering technique shows promise for new medical diagnostics, targeted drug delivery

Study identifies FGF21 protein as potential therapeutic agent for cardiovascular diseases, type 2 diabetes

Yale Cancer Center researchers identify cause of myeloma

Researchers devise lipid-based diets to relieve symptoms of Alzheimer's disease

Experimental nanoparticle therapy shows promise for fighting primary liver cancer

Study provides new insight into complex interchange that can raise blood levels of fat in type 1 diabetes

New technology could help identify, characterize biologically active molecules produced by living cells

Mild reduction in food intake slows development of autosomal-dominant polycystic kidney disease

Sphingosine kinase inhibitor slows castration-resistant prostate cancer cell growth

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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