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Eisai, Arena complete two Phase 1 registrational trials for once-daily formulation of lorcaserin

Eisai Inc. and Arena Pharmaceuticals, Inc. today announced the completion of two Phase 1 registrational clinical trials that Eisai and Arena believe demonstrate bioequivalence of an investigational once-daily extended release formulation of lorcaserin, as compared to the twice-daily immediate release formulation approved by the US Food and Drug Administration and marketed as BELVIQ.

13 Apr 2015

Study highlights the treatable causes of cerebellar ataxias

No cures are possible for most patients who suffer debilitating movement disorders called cerebellar ataxias. But in a few of these disorders, patients can be effectively treated with regimens such as prescription drugs, high doses of vitamin E and gluten-free diets, according to a study in the journal Movement Disorders.

24 Mar 2015

Two UH researchers named fellows of National Academy of Inventors

Two University of Houston faculty members have been named fellows of the National Academy of Inventors for their contributions to scientific and technological innovation.

17 Dec 2014

HDM introduces new Z1 Auto CPAP that customizes therapy by monitoring pressure requirements

On Friday, December 12, 2014 Human Design Medical, LLC (HDM) announced its Z1 Auto CPAP, which makes a quantum leap forward in CPAP therapy. The new Z1 Auto customizes therapy for each individual by monitoring pressure requirements thousands of times per night. Unlike fixed pressure CPAP devices, the Z1 Auto automatically responds to changes in breathing patterns and delivers maximum comfort by using the lowest possible therapy pressure throughout the sleep cycle.

13 Dec 2014

Non-use of bipolar medication typically follows careful ‘risk–benefit’ evaluation

An investigation into why and how patients with bipolar disorder manage their moods without medication has found that most individuals are initially motivated by concerns about side effects.

11 Dec 2014

Cerebellar cortical volume reduction specific to schizophrenia

Reduced cerebellar cortical volume occurs only in patients with schizophrenia, rather than all those with psychosis, say researchers.

10 Dec 2014

Depressive episodes hard to treat in continuous cycling bipolar disorder

Patients with bipolar disorder who switch directly between mania and depression without a period of euthymia have a poor response to short-term antidepressant treatment, study findings indicate.

3 Dec 2014

Lithium therapy duration not linked to thyroid effects

The risk of altered thyroid function does not increase with duration of lithium treatment in patients with bipolar disorder, research suggests.

27 Nov 2014

Flexure-based Electromagnetic Linear Actuator featured in 2014 R&D 100 Awards

A Flexure-Based Electromagnetic Linear Actuator (FELA) developed by the Singapore Institute of Manufacturing Technology, a research institute of the Agency for Science, Technology and Research, is the only locally-developed innovation featured in the 2014 R&D 100 Awards, an international competition that recognises the 100 most technologically-significant products introduced into the marketplace over the past year.

25 Nov 2014

Strict monitoring of lithium levels urged

Plasma levels of lithium above the advised range are associated with a transient reduction in kidney function, research shows.

19 Nov 2014

Point of care hemoglobin analyzer launched by EKF Diagnostics at Medica 2014

EKF, has introduced the DiaSpect TM POC hemoglobin analyzer at Medica.

From EKF Diagnostics 17 Nov 2014

People treated with lithium drug are at risk of acute kidney damage

People with bipolar disorder who are being treated with the drug lithium are at risk of acute kidney damage and need careful monitoring, according to new research from the University of East Anglia (UEA) and Norfolk and Suffolk NHS Foundation Trust.

14 Nov 2014

Experts review advances in understanding, treatment of bipolar disorder

Several lines of research have opened exciting new frontiers in scientific understanding and clinical management of bipolar disorder. Recent advances in bipolar disease research are described in this month's special issue of Harvard Review of Psychiatry.

11 Nov 2014

Novel therapeutic approaches to improve thyroid cancer outcomes

Novel therapeutic approaches to improve outcomes in thyroid cancer, for example using targeted delivery of cytotoxic drugs to tumor cells, will be among the topics featured in oral and poster presentations delivered at the 84th Annual Meeting of the American Thyroid Association, October 29-November 2, 2014, in Coronado, California.

30 Oct 2014

$Insulin resistance linked to treatment-refractory bipolar disorder$

Insulin resistance linked to treatment-refractory bipolar disorder

Patients with bipolar disorder who are insulin resistant are likely to also be refractory to mood-stabilising treatment, report researchers.

22 Oct 2014

Pointers for boosting prophylactic bipolar treatment reported

Patients with newly diagnosed bipolar disorder who have not previously used psychiatric drugs or have short hospital admissions should be targeted for prophylactic treatment, say researchers.

8 Oct 2014

Dendritic spine density also reduced in bipolar disorder

Patients with bipolar disorder have significant dendritic spine loss in the dorsolateral prefrontal cortex, postmortem findings show.

2 Oct 2014

Brain & Behavior Research Foundation to honor 8 scientists for achievements in psychiatric research

The Brain & Behavior Research Foundation will honor eight scientists with its 2014 Outstanding Achievement Prizes for work delving into psychiatric disorders that affect one in four people. The awards, which celebrate the transformative power of neuroscience and psychiatric research to improve the lives of people with mental illness, will be presented at the Foundation's National Awards Dinner at the Pierre Hotel.

30 Sep 2014

NRL scientists develop novel one-step process to form oxide nanoparticles

Scientists at the U.S. Naval Research Laboratory Materials Science and Technology Division have developed a novel one-step process using, for the first time in these types of syntheses, potassium superoxide (KO2) to rapidly form oxide nanoparticles from simple salt solutions in water.

25 Sep 2014

Longer looks: Lithium in the water; controlling cancer; recovering from brain injury

There are many kinds of cancer, but treatments have typically combatted them in one way only: by attempting to destroy the cancerous cells. Surgery aims to remove the entire growth from the body; chemotherapy drugs are toxic to the cancer cells; radiation generates toxic molecules that break up the cancer cells' DNA and proteins, causing their demise.

19 Sep 2014