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Penn engineers address the longstanding gap in reproductive health care with targeted RNA therapy

Pre-eclampsia is a leading cause of stillbirths and prematurity worldwide, occurring in 3 – 8 % of pregnancies. A disorder characterized by high maternal blood pressure, it results from insufficient vasodilation in the placenta, restricting blood flow from the mother to the fetus.

16 Feb 2023

Death of a zoo hippopotamus underscores the species’ susceptibility to SARS-CoV-2

A recent study investigated the death of a hippopotamus at a zoo in Hanoi, Vietnam.

16 Feb 2023

Study highlights the interconnectedness of autoimmunity and cancer

In a recent study published in the journal Immunity, researchers reviewed the T cell response in cancer and autoimmunity to propose strategies for more effective immunotherapies.

15 Feb 2023

Alternate-day fasting diet and exercise benefit the health of people with nonalcoholic fatty liver disease

Nutrition researchers at the University of Illinois Chicago studied 80 people with nonalcoholic fatty liver disease and found that those who followed an alternate-day fasting diet and exercised were able to improve their health.

14 Feb 2023

The efficiency of lifestyle intervention, orlistat, and experimental diet therapy in patients with obesity and metabolic-associated fatty liver disease

Researchers compared the effects of an experimental low-carbohydrate and high-protein diet and orlistat with that of a control diet to examine their impact on Asian MAFLD patients with obesity.

14 Feb 2023

Your money or your life: Patient on $50,000-a-week cancer drug fears leaving behind huge medical debt

After several rounds of treatment for a rare eye cancer — weekly drug infusions that could cost nearly $50,000 each — Paul Davis learned Medicare had abruptly stopped paying the bills.

14 Feb 2023

High doses of cannabidiol may increase the effects of THC in edible cannabis products

Contrary to some common claims, a study led by Johns Hopkins Medicine researchers found that relatively high doses of cannabidiol (CBD) may increase the adverse effects of delta-9-tetrahydrocannabinol (THC), the main active ingredient in cannabis that can cause a mood alteration or a "high" sensation.

13 Feb 2023

The immunogenicity of two leading malaria vaccine candidates delivered as mRNA-LNP vaccines

Researchers evaluated the immunogenicity of two vaccine candidates, Pfs25 and PfCSP, based on the mRNA-lipid nanoparticle (LNP) platform.

13 Feb 2023

Fear and anxiety during the COVID-19 pandemic associated with new alcohol use disorder diagnoses

Researchers explored the association between severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections and new diagnoses of alcohol use disorder (AUD) in the two years since the onset of the coronavirus disease 2019 (COVID-19) pandemic.

13 Feb 2023

Pathological significance of CEACAMS 1, 5, and 6 in cancer biology, immunology and inflammatory disease

A new review was published in Genes & Cancer on February 1, 2023, entitled, "CEACAMS 1, 5, and 6 in disease and cancer: interactions with pathogens."

10 Feb 2023

UVA researchers discover a key trigger for non-alcoholic fatty liver disease

University of Virginia School of Medicine researchers have discovered a key trigger for non-alcoholic fatty liver disease, a mysterious condition that causes fat to build up in the liver for no clear reason.

9 Feb 2023

Computer software can predict what happens when certain gene networks are disrupted

Computer software developed at Washington University School of Medicine in St. Louis can predict what happens to complex gene networks when individual genes are missing or dialed up more than usual.

9 Feb 2023

Protein activity found to be more dysregulated in the blood of patients with alcohol-associated hepatitis

Biochemist Jon Jacobs has analyzed the blood of patients with diseases and conditions such as Ebola, cancer, tuberculosis, hepatitis, diabetes, Lyme disease, brain injury and influenza.

9 Feb 2023

Researchers find possible genetic basis and mouse model for nonalcoholic steatohepatitis

A mutant or damaged gene may be a cause of a severe, mysterious form of nonalcoholic fatty liver disease, University of Illinois Urbana-Champaign researchers have found.

9 Feb 2023

Exercise can be used as a treatment for nonalcoholic fatty liver disease

The 150 minutes of moderate to intense aerobic activity per week that is recommended by the U.S. Department of Health and Human Services can significantly reduce liver fat, according to new research by Penn State College of Medicine researchers.

9 Feb 2023

Exercise can lead to meaningful reductions in liver fat for patients with NAFLD, research confirms

Penn State College of Medicine researchers confirmed exercise can lead to meaningful reductions in liver fat for patients with nonalcoholic fatty liver disease.

8 Feb 2023

Patient's satisfaction with physician associated with completion of bariatric surgery

Patients' satisfaction with their physicians may influence their decisions to undergo bariatric surgery, according to a multicenter study involving UT Southwestern and the UTHealth School of Public Health published in JAMA Network Open.

8 Feb 2023

Recent findings on T-cell immunity induced by SARS-CoV-2 infection and vaccination in immunocompromised individuals

Researchers discussed studies that explored T-cell immunity induced by SARS-CoV-2 infection and COVID-19 vaccination in cancer patients, individuals with HIV, and recipients of solid organ transplants.

8 Feb 2023

Researchers highlight the dysregulation of hepatokines in people with NAFLD

Non-alcoholic fatty liver disease (NAFLD) is an important risk factor for type 2 diabetes and cardiovascular diseases.

7 Feb 2023

A review of innate immunity relevant to SARS-CoV-2 and COVID-19

In a recent study published in The New England Journal of Medicine, researchers reviewed selected acute-phase proteins concerning their production, structure, and function.

7 Feb 2023

Liver News and Research

Penn engineers address the longstanding gap in reproductive health care with targeted RNA therapy

Death of a zoo hippopotamus underscores the species’ susceptibility to SARS-CoV-2

Study highlights the interconnectedness of autoimmunity and cancer

Alternate-day fasting diet and exercise benefit the health of people with nonalcoholic fatty liver disease

The efficiency of lifestyle intervention, orlistat, and experimental diet therapy in patients with obesity and metabolic-associated fatty liver disease

Your money or your life: Patient on $50,000-a-week cancer drug fears leaving behind huge medical debt

High doses of cannabidiol may increase the effects of THC in edible cannabis products

The immunogenicity of two leading malaria vaccine candidates delivered as mRNA-LNP vaccines

Fear and anxiety during the COVID-19 pandemic associated with new alcohol use disorder diagnoses

Pathological significance of CEACAMS 1, 5, and 6 in cancer biology, immunology and inflammatory disease

UVA researchers discover a key trigger for non-alcoholic fatty liver disease

Computer software can predict what happens when certain gene networks are disrupted

Protein activity found to be more dysregulated in the blood of patients with alcohol-associated hepatitis

Researchers find possible genetic basis and mouse model for nonalcoholic steatohepatitis

Exercise can be used as a treatment for nonalcoholic fatty liver disease

Exercise can lead to meaningful reductions in liver fat for patients with NAFLD, research confirms

Patient's satisfaction with physician associated with completion of bariatric surgery

Recent findings on T-cell immunity induced by SARS-CoV-2 infection and vaccination in immunocompromised individuals

Researchers highlight the dysregulation of hepatokines in people with NAFLD

A review of innate immunity relevant to SARS-CoV-2 and COVID-19

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