Liver News and Research

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No to over the counter statin!

Last Friday an FDA expert panel voted overwhelmingly against the over-the-counter sale of Merck's cholesterol lowering drug Mevacor (lovastatin). Mevacor is one of a number of drugs known as "statins" which are widely considered to be the most effective drugs for the treatment of high cholesterol. Statins work by inhibiting a liver enzyme used in the manufacture of cholesterol.

17 Jan 2005

Major partnership with National Institute of Allergy and Infectious Diseases for Narhex Life Sciences

Australian drug specialist Narhex Life Sciences, has announced a partnership with one of the world’s foremost US medical research centres to evaluate its protease inhibitor Nar DG 35 Prodrug for its activity against Hepatitis C and SARS viruses.

12 Jan 2005

Using models to understand malaria

Malaria is one of the world's major killers. More than 500 million people live in epidemic regions and some 2 million - mostly children - die each year. And each year, drug resistance increases in the malarial parasite, Plasmodium falciparum, and the search for new treatments becomes more desperate.

12 Jan 2005

Elevated glucose levels and diabetes associated with a greater risk for cancer

New research involving more than one million people indicates that having high fasting serum glucose levels and diabetes are risk factors for several major cancers, according to a study in the January 12 issue of JAMA.

12 Jan 2005

Elevated blood sugar levels and diabetes are risk factors for developing several types of cancer and mortality

The researchers followed over 1.2 million Koreans for 10 years, tracking new cancer cases and deaths from cancer. Study participants with diabetes, as well as those without diabetes and higher fasting blood sugar levels, were more likely to develop cancer or to die from cancer.

11 Jan 2005

Core promoter mutants of Hepatitis B Virus e Antigen associated with development of fulminant hepatitis and liver cancer

Scientists in Brown Medical School, Providence, USA, have found that core promoter mutants of Hepatitis B Virus e Antigen replicate at up to 10-fold higher levels in transfected human hepatoma cells than the wild-type virus.

9 Jan 2005

Pegylated interferon alfa-2b offers the best treatment option for people with chronic hepatitis B infection

Harry Janssen (Erasmus University Medical Centre, Rotterdam, Netherlands) and colleagues assessed whether combination treatment with pegylated interferon alfa-2b and the antiviral agent lamivudine was more efficacious in treating chronic hepatitis B infection than pegylated interferon alfa-2b therapy alone.

7 Jan 2005

Strong association between high levels of hyaluronic acid and severe osteoarthritis

A chronic degenerative joint disease, osteoarthritis (OA) is a common cause of pain and disability among older Americans. OA of the knee affects up to 6 percent of the older population, while OA of the hip affects about another 3 percent. While treatments vary, there is hope that early intervention – before joint destruction can be clearly seen and measured on an X-ray image-will improve outcomes.

7 Jan 2005

Potential cure for lymphoma in HIV patients

Stem cell transplants have become the standard of care for patients with relapsed lymphoma, but not for patients who suffer from both this disease and HIV.

7 Jan 2005

Peginterferon alfa-2b produced sustained responses in patients with chronic hepatitis B

Results from a large international clinical study reported in this week's issue of The Lancet showed that peginterferon alfa-2b produced sustained responses in patients with chronic hepatitis B. The investigator-initiated study is the largest clinical trial to date with peginterferon alfa-2b therapy for chronic hepatitis B.

7 Jan 2005

Mutated gene may provide better idea of how cancer develops and progresses

Scientists are taking the first steps to find out how a gene that is mutated in many cancer cells functions in healthy cells.

6 Jan 2005

New hope for millions of patients suffering from liver damage (cirrhosis)

Millions of patients suffering from liver damage (cirrhosis) and failure may benefit from research by the Universities of Edinburgh and Southampton which may lead to new life-saving treatments. There is currently no cure for liver cirrhosis and a patient's only hope of survival is to receive a liver transplant.

5 Jan 2005

Link between body-mass index and oral-contraceptive failure

Overweight and obese women who take oral contraceptives are 60 percent to 70 percent more likely to get pregnant while on the birth-control pill, respectively, than women of lower weight, according to new findings from Fred Hutchinson Cancer Research Center that will be published in the January issue of Obstetrics & Gynecology.

30 Dec 2004

New technique for tracking gene regulators

Finding out where gene-regulator proteins bind to DNA and identifying the genes they regulate just got a step easier thanks to a new technique developed by scientists at the U.S. Department of Energy’s Brookhaven National Laboratory.

28 Dec 2004

FDA go ahead for first of kind genetic lab test

The U.S. Food and Drug Administration (FDA) has approved the marketing of the first laboratory test system that will allow physicians to consider unique genetic information from patients in selecting medications and doses of medications for a wide variety of common conditions such as cardiac disease, psychiatric disease, and cancer.

27 Dec 2004

Teen concerns about inhalants and painkiller use

According to the Department of Health and Human Services, results from the annual Monitoring the Future (MTF) survey indicate an almost 7 percent decline of any illicit drug use in the past month by 8th, 10th, and 12th graders combined from 2003 to 2004.

21 Dec 2004

Push for mandatory health warnings on all alcohol products

Australian Medical Association President, Dr Bill Glasson, said today the AMA is calling on the Australian Federal Government to legislate for health warnings on all alcohol products.

21 Dec 2004

Nearly 6 million Americans turned to complementary and alternative medicine because of costs

Nearly 6 million American adults turned to complementary and alternative medicine (CAM) in the past year to treat such conditions as depression and chronic pain because conventional medical treatment was too expensive, according to a national study released today by the Center for Studying Health System Change (HSC).

20 Dec 2004

Polls show more teen girls see "alcopop" ads than women age 31-44

The American Medical Association (AMA) released the results of two nationwide polls today that reveal the extent of underage consumption and marketing exposure to "alcopops" or so-called "girlie drinks." The AMA expressed concern that hard-liquor brands are using these sweet-flavored malt beverages as "gateway" beverages to attract less-experienced drinkers.

20 Dec 2004

Researchers discover clues to cirrhosis

Researchers at the University of Essex have found new biochemical indicators of cirrhosis in blood plasma which could help detect the disease in its early stages.

20 Dec 2004

Liver News and Research

No to over the counter statin!

Major partnership with National Institute of Allergy and Infectious Diseases for Narhex Life Sciences

Using models to understand malaria

Elevated glucose levels and diabetes associated with a greater risk for cancer

Elevated blood sugar levels and diabetes are risk factors for developing several types of cancer and mortality

Core promoter mutants of Hepatitis B Virus e Antigen associated with development of fulminant hepatitis and liver cancer

Pegylated interferon alfa-2b offers the best treatment option for people with chronic hepatitis B infection

Strong association between high levels of hyaluronic acid and severe osteoarthritis

Potential cure for lymphoma in HIV patients

Peginterferon alfa-2b produced sustained responses in patients with chronic hepatitis B

Mutated gene may provide better idea of how cancer develops and progresses

New hope for millions of patients suffering from liver damage (cirrhosis)

Link between body-mass index and oral-contraceptive failure

New technique for tracking gene regulators

FDA go ahead for first of kind genetic lab test

Teen concerns about inhalants and painkiller use

Push for mandatory health warnings on all alcohol products

Nearly 6 million Americans turned to complementary and alternative medicine because of costs

Polls show more teen girls see "alcopop" ads than women age 31-44

Researchers discover clues to cirrhosis

Hasret Altan-Martin

Speeding Up Sample Preparation to Accelerate Analytical Chemistry

Ask the Expert: 7 Questions about Colorectal Cancer & Non-invasive Fecal DNA Testing

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